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Marc Soco

@msocomd

๐Ÿ‡ต๐Ÿ‡ญ Internist โ€ข Nephrologist ๐Ÿ“ Cebu, Philippines โœˆ๏ธ Balancing clinical work with a passion for travel and photography ๐Ÿ’ก #NephJC Intern โ€ข #GlomCon Alum โ€˜23-24 โ€ข #NephSIM โ€˜20-21

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13.11.2024
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Latest posts by Marc Soco @msocomd

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โ€œThe kidneys make the stuff of philosophy itself.โ€ โ™ฅ๏ธ Thank you @msocomd.bsky.social

11.03.2026 09:34 ๐Ÿ‘ 10 ๐Ÿ” 4 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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๐Ÿ‘‰Before we start, a few reminders! Are you new to #NephJC ? Not sure what to do or how this works? Here is a quick rundown, an infographic made by Sinead Stoneman

25.02.2026 01:45 ๐Ÿ‘ 2 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

โฐ90 minutes left until #NephJC chat

Hemoglobin targets have swung widely:
๐Ÿ“ˆ Normalize Hb โ†’ CV harm signal
๐Ÿ“‰ Conservative targets โ†’ persistent symptoms
Have we found the sweet spot yet?

25.02.2026 00:30 ๐Ÿ‘ 3 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

โฐ2 hours until #NephJC chat
Anemia in CKD has shaped nephrology for decades
ESAs, iron, transfusions, now HIF-PHIs
But one question remains:
๐Ÿ‘‰ Are we treating anemia optimally or cautiously?

25.02.2026 00:00 ๐Ÿ‘ 1 ๐Ÿ” 1 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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2026 KDIGO Anemia Management Guidelines โ€” NephJC This week, we will discuss 2026 KDIGO anemia management in patients with kidney disease

#NephSky #MedSky
๐ŸฉธBlood is thicker than water ๐ŸŒŠ
Thankfully we thinned out the 2026 KDIGO Anemia Guidelines for you to peruse.
Come discuss what's new.
Tuesday 2/24/26 at 9pm EST on Bluesky!
Summary by @jeyakumarmeyyappan.bsky.social
www.nephjc.com/news/kdigo-anemia

24.02.2026 03:03 ๐Ÿ‘ 14 ๐Ÿ” 9 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Anemia research in CKD has had so much big fraud stories (which we donโ€™t touch in the #NephJC write up) given the $$$

- the Normal Hct shady analysis from Amgen and PIs that @nejm.org allowed and still stays there
- the Roxadustat p-hacking that brought down Fibrogen and tainted HIF-PHIs

24.02.2026 13:27 ๐Ÿ‘ 7 ๐Ÿ” 1 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

Marc Soco, nephrologist from the Philippines and flozinator, looking forward to the discussion. No COI #NephJC

11.02.2026 02:07 ๐Ÿ‘ 5 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
Pretest and post-test counseling. (A) The components of pretest counseling. (B) The components of post-test counseling. The goals of the counseling session are depicted in rectangular shapes. Questions that the clinicians should ask themselves are depicted in the white clouds. VUS, variants of uncertain significance.

Pretest and post-test counseling. (A) The components of pretest counseling. (B) The components of post-test counseling. The goals of the counseling session are depicted in rectangular shapes. Questions that the clinicians should ask themselves are depicted in the white clouds. VUS, variants of uncertain significance.

nice (and free) review of genetic testing and counselling in renal disease

journals.lww.com/kidney360/fu...

in @asnpublications.bsky.social #Kidney360

#NephSky #Genetics

28.01.2026 14:12 ๐Ÿ‘ 5 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Totally agree. But given the signal for reduced hypoK and SCDโ€ฆ tempting to think K might be contributing independently #NephJC

28.01.2026 02:19 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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a woman is making a funny face and the words so sassy are above her face ALT: a woman is making a funny face and the words so sassy are above her face

#NephJC

28.01.2026 02:15 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Feels unlikely to be pure coincidence. Potassium may be part of the mechanism, not just a bystander #NephJC

28.01.2026 02:13 ๐Ÿ‘ 3 ๐Ÿ” 0 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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In patients with CV disease, the โ€œnormalโ€ range may be misleading
Mortality is actually higher at Kโบ 3.5โ€“4.0 mmol/L
while high-normal levels (4.5โ€“5.0) are associated with lower mortality ๐Ÿ‘€ #NephJC
pubmed.ncbi.nlm.nih....

28.01.2026 02:10 ๐Ÿ‘ 7 ๐Ÿ” 3 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 0

Glad to have you here! Always great to hear from someone whoโ€™s been intentionally targeting higher potassium in practice. Looking forward for some insights #NephJC

28.01.2026 02:09 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0

Hey everyone! Marc here, joining from the Philippines. No COI #NephJC

28.01.2026 02:05 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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๐ŸŒ๐Ÿฅ‘Can pushing Kโบ to the high-normal range reduce ICD shocks and hospitalizations?

๐ŸŽจ #Visualabstract by @jeyakumarmeyyappan.bsky.social

โฐ #NephJC chat on Jan 27, 9 pm EST

www.nephjc.com/news/2026/1/...

26.01.2026 09:05 ๐Ÿ‘ 13 ๐Ÿ” 10 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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ยฟElevar el Kโบ al rango alto-normal puede reducir las descargas del DAI y las hospitalizaciones?

๐ŸŽจResumen visual por @jeyakumarmeyyappan.bsky.social
โœ๏ธTraducido por @dramiliflores.bsky.social

www.nephjc.com/news/2026/1/...

26.01.2026 09:13 ๐Ÿ‘ 5 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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POTCAST- K+ Pop and Arrhythmia Drop โ€” NephJC This week, we will discuss the POTCAST trial. It is a cardiology trial - but potassium belongs to nephrology.

Oh, the weather outside is frightful ๐Ÿฅถ๐Ÿฅถ
But #NephJC is so delightful,
and since you've no place to go #NephSky...
Come discuss POTCAST: potassium goals and cardiac arrhythmias 1/27/26 at 9pm EST on #Bluesky
Summary by @shelliefravel.bsky.social @salinesolut.bsky.social
www.nephjc.com/news/potcast

26.01.2026 21:47 ๐Ÿ‘ 13 ๐Ÿ” 9 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
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Top Stories in Nephrology 2025 โ€” NephJC 2025 was rich in successful stories. Here are the top 10 that impressed our audience.

It's 2026!๐ŸŽ‰
We will be counting down the Top Ten Nephrology Stories of 2025 on 1/6/26 at 9 pm EST.
Join us on TWITTER (it will always be Twitter to us).
Come on by #NephJC faithful for a lively discussion! You picked & we're count'em down.
www.nephjc.com/news/2025/1/3/top-stories-in-nephrology-2025

03.01.2026 19:03 ๐Ÿ‘ 14 ๐Ÿ” 13 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 3
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1/10

Last #NephJC we discussed dialysis frequency in AKI-D #TenPostNephJC

We sought to answer an age-old question: Is less is really more? Or less is just simply what it isโ€ฆ.less?

pubmed.ncbi.nlm.nih.gov/41201895/

19.12.2025 12:22 ๐Ÿ‘ 8 ๐Ÿ” 8 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0

If hemodynamically stable and non-oliguric, then probably no. Ultimately, we treat the patient, not the numbersโ€ฆ using labs to inform, not dictate, decisions #NephJC

17.12.2025 02:27 ๐Ÿ‘ 1 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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a woman in a blue jacket is sitting in front of a door and says oh yes . ALT: a woman in a blue jacket is sitting in front of a door and says oh yes .

#NephJC Popular opinion:

17.12.2025 02:10 ๐Ÿ‘ 0 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Have you ever โ€œwithheldโ€ dialysis because the patient looked good despite questionable labs?
Did you feel brave or nervous? ๐Ÿ˜…
We restrict fluids, potassium, phosphorusโ€ฆ
But what about restricting dialysis itself?
Letโ€™s talk. #NephJC

17.12.2025 02:00 ๐Ÿ‘ 7 ๐Ÿ” 2 ๐Ÿ’ฌ 3 ๐Ÿ“Œ 0
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Hi everyone ! Marc here from the Philippines ๐Ÿ‡ต๐Ÿ‡ญ sharing this โ€œimprisonmentโ€ from Jerรณnimos Monastery in Lisbon ๐Ÿ‡ต๐Ÿ‡น. From historic monasteries to modern trials, letโ€™s LIBERATE-D our thinking. Looking forward to a great discussion! No COI. #NephJC

17.12.2025 02:08 ๐Ÿ‘ 4 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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LIBERATE-D: El Resumen Visual โ€” NephJC En pacientes con lesiรณn renal aguda en diรกlisis, se evaluรณ si una estrategia mรกs conservadora impacta en la recuperaciรณn renal. ยฟSerรก que menos es mรกs? รšnete a la discusiรณn del ensayo clรญnico LIBERATE...

Gracias! @dramiliflores.bsky.social #NephSky
LIBERATE-D: El Resumen Visual โ€” #NephJC

www.nephjc.com/news/2025/12/14/liberate-d-el-resumen-visual

15.12.2025 14:56 ๐Ÿ‘ 13 ๐Ÿ” 6 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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Dialyze Less, Recover More? AKIโ€™s Chance to Get LIBERATE-D โ€” NephJC This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.

www.nephjc.com/news/...
Check out the excellent #NephJC summary by @msocomd.bsky.social and @sejalplakhani.bsky.social

17.12.2025 02:04 ๐Ÿ‘ 9 ๐Ÿ” 4 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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Dialyze Less, Recover More? AKIโ€™s Chance to Get LIBERATE-D โ€” NephJC This week, we will discuss whether less is more when it comes to discontinuing dialysis in patients with AKI and a chance to recover.

Join us for the last #NephJC of 2025, 12/16/25 at 9pm EST!๐Ÿฅณ
How soon should we withhold dialysis in AKI?
We're discussing the LIBERATE-D trial #NephSky
This one might just change your mind ๐Ÿง ๐Ÿง 
Blog by @msocomd.bsky.social and @sejalplakhani.bsky.social
www.nephjc.com/news/liberated-aki

15.12.2025 14:40 ๐Ÿ‘ 12 ๐Ÿ” 12 ๐Ÿ’ฌ 2 ๐Ÿ“Œ 1
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PISCES: The Visual Abstract โ€” NephJC Curious how n-3 PUFAs may cut serious cardiovascular events in dialysis? ๐ŸŸ A big signal, a big dose, and a big discussion ahead โ€” donโ€™t miss this #NephJC! Check out the VA made by our master Brian...

Holy Mackerel! ๐ŸŸ
๐ŸฆœAhoy matey! Could fish oil unlock the mysteries of increased CV mortality in ESRD? ๐Ÿดโ€โ˜ ๏ธ #NephJC
Join us for a lively trawling trip 12/2/25 ๐Ÿ›ฅ๏ธat 9pm EST
Check out the PISCES VA by @brianrifkin.bsky.social
www.nephjc.com/news/piscesva

01.12.2025 18:46 ๐Ÿ‘ 14 ๐Ÿ” 11 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 1
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1/10
Last #NephJC we discussed the ORIGIN 3 trial which investigated the use of Atacicept in IgAN #TenPostNephJC
Read the article ๐Ÿ‘‡
www.nejm.org/doi/10....

20.11.2025 00:34 ๐Ÿ‘ 9 ๐Ÿ” 9 ๐Ÿ’ฌ 1 ๐Ÿ“Œ 0
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a man in a suit and tie is applauding with the words good job written below him ALT: a man in a suit and tie is applauding with the words good job written below him

awesome job @shelliefravel.bsky.social !! #nephJC

19.11.2025 03:00 ๐Ÿ‘ 2 ๐Ÿ” 0 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0
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T4d:

Thatโ€™s all partners ๐Ÿค 

From here until the end of the year we will be catching up on all the late-breaking and simultaneous publications from #KidneyWk 2025. ๐Ÿ˜ฎโ€๐Ÿ’จ

Ainโ€™t no party like a #NephJC party!

19.11.2025 02:55 ๐Ÿ‘ 7 ๐Ÿ” 3 ๐Ÿ’ฌ 0 ๐Ÿ“Œ 0