CoPhy team

Currently recruiting 2 postdoc fellows, 1 Ph.D student and 1 research assistant to work on research projects about the EEG/fMRI mechanisms underlying temporal cognition and their modulations using VR.
DM if interested!

The alpha rhythm: from physiology to behaviour | Physiological Reviews | American Physiological Society The alpha rhythm, first identified by Hans Berger 100 years ago, is the dominant non-invasive electrophysiological signature of the healthy human brain in the awake state. For decades, it was believed that the alpha rhythm reflected rest or idling; however, this perspective changed in the 2000s when researchers found that alpha oscillations increase with cognitive demands. This discovery led to a paradigm shift, demonstrating that alpha oscillations reflect the functional inhibition of brain regions that are not needed for a specific task, thereby directing information to task-specific areas. We have reviewed the physiological mechanisms involved in generating alpha oscillations, which has informed computational models explaining how these oscillations emerge within physiologically realistic networks. At the behavioural level, alpha oscillations are strongly modulated across nearly all cognitive paradigms tested in humans, reflecting the allocation of computational resources within the active brain network. Research in individuals with attention-related issues has highlighted their impaired ability to modulate alpha oscillations, which is associated with performance deficits. Therefore, further exploration of alpha oscillations has the potential to uncover causal mechanisms underlying attention problems, such as those related to ADHD and ageing. Lastly, advancements in technology are opening new avenues for characterising alpha oscillations in ecologically valid settings and across the lifespan. This progress sets the stage for exploring the role of alpha oscillations in cognitive development and their functioning in natural environments.

Curious about our good old alpha rhythm, but not sure where to start or how to deepen your understanding? Dive into the newly released extensive review paper by Ole Jensen & Mathilde Bonnefond! It offers an overview of the field and highlights the key questions that will shape future research

Thrilled to share this work, spearheaded by the Danc lab (led by James Bonaiuto) @danclab.bsky.social, in collaboration with us, especially Matteo Maspoli @mattgmasp.bsky.social and Danila Shelepenkov @shpen.bsky.social, and other groups who share the belief that MEG still has untapped potential!

Mistral AI surfs vibe coding tailwinds with new coding models | TechCrunch French AI startup Mistral today launched Devstral 2, a new generation of its AI model designed for coding, as the company seeks to catch up to bigger AI labs like Anthropic and other coding-focused LLMs.

French AI startup Mistral today launched Devstral 2, a new generation of its AI model designed for coding, as the company seeks to catch up to bigger AI labs like Anthropic and other coding-focused LLMs.

An exciting post-doc postion in the @cophy.bsky.social
recrutement.inria.fr/public/class...

Check out this exciting postdoc opportunity in James Bonaiuto’s lab in Lyon!
The project focuses on laminar MEG, beta bursts, and comparisons with laminar e-phys in monkeys.
emploi.cnrs.fr/Offres/CDD/U...

We are seeking a highly motivated PhD candidate for an exciting potential INRIA-Inserm project on:
Multiscale brain rhythms in healthy and epileptic conditions: computational modeling insights for clinical applications.

More information here: elifkoksal.github.io/positions.html!

This paper describes a way to incorporate beta bursts in pipelines of motor imagery BCI and shows that beta bursts outperform signal power in terms of classification accuracy and information transfer rate

Surfing beta burst waveforms to improve motor imagery-based BCI Abstract. Our understanding of motor-related, macroscale brain processes has been significantly shaped by the description of the event-related desynchronization (ERD) and synchronization (ERS) phenome...

Check out our recent article by Sotirios Papadopoulos, Jérémie Mattout, @maciekszul.bsky.social, @danclab.bsky.social et al.!
direct.mit.edu/imag/article...

and an ealer version here hal.science/hal-04775585/

Here is the free access version (until the 31st of January) authors.elsevier.com/a/1kFXN_V1r-...

Unfortunately, we could not cite all the papers we wanted to cite.

We also discuss alternative mechanisms, also based on alpha oscillations, that help resist distraction. Some of these mechanisms involve alpha oscillations in the parietal region and the ventral attention network.

In this paper, we discuss the ongoing debate regarding whether alpha oscillations play a role in suppressing the processing of distractors by modulating gain in early sensory regions. We hope it is considered balanced and provides guidance for future work

Hi all,
We are happy to announce that our paper regarding the roles of alpha oscillations in resisting distraction is now online doi.org/10.1016/j.ti...

This paper describes a neural mass model that integrates plasticity under epileptic activity. The model helps to better understand the formation of epileptogenic networks in the presence of an epileptic focus

Expansion of epileptogenic networks via neuroplasticity in neural mass models Author summary Repetitive epileptic activity leads to a large variety of plastic changes in brain. Understanding the mechanism and its time course can indicate windows of opportunity for preventing th...

Elif Köksal Ersöz, a recently recruited researcher at INRIA in the team, has just published a paper in PLoS Computational Biology on her work done in Rennes with Fabrice Wendling. journals.plos.org/ploscompbiol...

Announcing Release 3 of The Open MEG Archives (OMEGA) — Baillet Lab [ neuroSPEED ] We're thrilled to announce the latest expansion of The Open MEG Archives (OMEGA). Dive into over 150 hours of task-free MEG recordings from 644 participants , including individuals with Parkinson’s...

Excited to deliver Release 3 of The Open MEG Archives:🧠🧲
644 participants ∣ over 150 hrs of task-free recordings ∣ incl. Parkinson’s disease, ADHD, chronic pain + 444 healthy controls ∣ defaced structural MRI volumes ∣ individual questionnaire data.
www.neurospeed-bailletlab.org/news/announc...

Visual Processing by Hierarchical and Dynamic Multiplexing The complexity of natural environments requires highly flexible mechanisms for adaptive processing of single and multiple stimuli. Neuronal oscillations could be an ideal candidate for implementing su...

Tommy Clausner, Ole Jensen and I are pleased to announce that our recent opinion paper is now online! www.eneuro.org/content/11/1...
It covers a relatively broad field of research but we hope you will find some ideas interesting there.

MEG-UKI 2024 is coming to Birmingham! Mon 28th - Thu 31st October We are teaming up with our colleagues in the world of OPMs to bring you four days of cutting-edge neuroscience and Magnetoencephalography.
More info below, and on our site: (t.co/tSKytguX61)

Thanks in advance!

On Thursday, don't miss out Sotirios Papadopoulos, who will present his work on motor imagery decoding using beta beta bursts at Neural Traces 2024! Neuraltraces2024.org

How to address spatial normalization challenges when creating an MRI atlas of the pituitary gland? A solution is proposed in this new article

MRI atlas of the pituitary gland in young female adults - Brain Structure and Function The probabilistic topography and inter-individual variability of the pituitary gland (PG) remain undetermined. The absence of a standardized reference atlas hinders research on PG volumetrics. In this...

New article! MRI atlas of the pituitary gland in young female adults
link.springer.com/article/10.1...

🚨Job alert!🚨 Are you curious about curiosity, and looking for a post-doc position? Then please consider applying: www.ru.nl/en/working-a...
Feel free to e-mail/DM me if you have questions.

Thanks very much for sharing/re-posting!

Is controlling a brain-computer interface just a matter of presence of mind? The limits of cognitive-motor dissociation Brain-computer interfaces (BCI) are presented as a solution for people with global paralysis, also known as locked-in syndrome (LIS). The targeted population includes the most severe patients, with no residual eye movements, who cannot use any communication device (Complete LIS). However, BCI reliability is low precisely in these cases, technical pitfalls being considered responsible so far. Here, we propose to consider also that global paralysis could have an impact on cognitive functions that are crucial for being able to control a BCI. We review a bundle of arguments about the role of motor structures in cognition. Especially, we uncover that these patients without oculomotor activity often have injuries in more 'cognitive' structures such as the frontal eye field or the midbrain, exposing them to cognitive deficits further than canonical LIS population. We develop a hypothesis about the putative role of the motor system in (covert) attention, a capacity which is a prerequisite for most BCI paradigms and which should therefore be both better assessed in patients and considered.

These results led us to question the impact of severe paralysis on attentional control in this preprint: arxiv.org/abs/2310.00266

The challenge of controlling an auditory BCI in the case of severe motor disability - Journal of NeuroEngineering and Rehabilitation Background The locked-in syndrome (LIS), due to a lesion in the pons, impedes communication. This situation can also be met after some severe brain injury or in advanced Amyotrophic Lateral Sclerosis ...

Is it possible to control an auditory BCI when being in severe motor disability ? Some answers in this COPHY clinical study from Seguin, Maby, […], Mattout doi.org/10.1186/s129....

Recent findings suggest that beta band brain activity occurs in bursts rather than sustained oscillations. In this study we analyze EEG recordings of hand motor imagery BCI tasks and show that on the single-trial level beta burst rate modulations are advantageous to beta power in terms of decoding.

New article from Sotirios Papadopoulos, Jérémie Mattout, @maciekszul.bsky.social @danclab.bsky.social et al.: iopscience.iop.org/article/10.1..., more info below ⬇️

New article from our team! 📰 Bonnet, P., Bonnefond, M., & Kosem, A. (2024). What is a Rhythm for the Brain? The Impact of Contextual Temporal Variability on Auditory Perception. Journal of Cognition, 7(1): 15, pp. 1–16. DOI: doi.org/10.5334/joc.344

Thank you! 🤗