Paddy Monahan's Avatar

Paddy Monahan

@paddymonahan

#longcovid since 2020 | Software Engineer | Co-founder @vindarahealth

28
Followers
56
Following
10
Posts
27.05.2025
Joined
Posts Following

Latest posts by Paddy Monahan @paddymonahan

Hi there. We're working on it. It takes time to get our legal entities setup and registered in each state, along with clinician licensing and other hurdles. We'll publish more information soon on our rollout!

02.03.2026 18:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Millions with #LongCOVID, #MECFS, #POTS, #MCAS and other complex illnesses have been gaslit, dismissed, and forgotten by a system that doesn't understand their conditions. They deserve better. That starts with believing patients.

26.02.2026 11:35 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

When naming @vindarahealth.bsky.social, we wanted one word to capture our mission. Vindara comes from the Latin vindico: to vindicate.

26.02.2026 11:35 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Delighted to announce we’re opening the waitlist for
@vindarahealth.bsky.social, a new telehealth clinic built specifically for complex illness, co-founded by Dr. David Kaufman MD

Launching soon in WA, CO and AZ. More info on our rollout coming soon!

#LongCovid #MECFS #POTS #mcas

17.02.2026 11:54 πŸ‘ 4 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

6/ Thanks to
@CallumThomas96
@DrMark_Faghy
@DerbyUni
@StellenboschUni
@JanPretorius98
@dbkell.bsky.social
@drmassimonunes

for this amazing work!

28.05.2025 11:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

5/ Why this matters

One of the clearest explanations of PEM to date. It shows that even gentle exercise can trigger clot fragmentation and inflammation. This should be another wake-up call for those still pushing blanket Graded Exercise Therapy.

28.05.2025 11:17 πŸ‘ 0 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

4/ What they found

- Large microclots fragmented into smaller ones
- Inflammation markers surged post-exercise
- Oxygen delivery got worse on Day2

Pointing to vascular injury+systemic inflammation, even from modest exertion. Matching what many patients experience after activity

28.05.2025 11:17 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

3/ How was it done?

Participants did two submaximal cardiopulmonary exercise tests (CPETs), a common way to assess exercise tolerance. They chose participants who had a low risk of PEM. (imagine how bad this is for those with severe PEM)

28.05.2025 11:17 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

2/ What did they do?

46 people with Long COVID (low risk of PEM) did two gentle exercise tests, 24hrs apart.

They analysed:
– Microclot size & count
– Inflammatory cytokines
– Oxygen uptake

Aiming see how the body reacts after activity, not just during

28.05.2025 11:17 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Exercise-induced Changes in Microclotting and Cytokine Levels Point to Vascular Injury and Inflammation in People with Long COVID Background: Long COVID is a persistent and episodic multi-system condition that impacts quality of life and functional status. Underlying pathologies include viral persistence, endothelial dysfunction...

1/ Fantastic new preprint from
@resiapretorius.bsky.social @CallumThomas96 @DrMark_Faghy and co. This new study suggests that even light exercise may worsen #LongCOVID. by breaking up #microclots and triggering inflammation.

researchsquare.com/article/rs-6...

Here’s what they found:

28.05.2025 11:17 πŸ‘ 13 πŸ” 4 πŸ’¬ 1 πŸ“Œ 0