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Gary Álvarez

@garinho29

Curious neurologist focused on Neuroimmunology and Neurometabolic disorders

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14.12.2024
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Latest posts by Gary Álvarez @garinho29

It was a real pleasure sharing the session with you. Thank you so much for helping me feel comfortable in my first presentation at EAN.

24.06.2025 07:59 👍 2 🔁 0 💬 0 📌 0

IL-10 in Systemic Lupus Erythematosus: Balancing Immunoregulation and Autoimmunity

🔑involved in inflammatory and immune processes in SLE.
🔹IL-10 did not correlate with disease activity, organ in-
volvement, or treatment response.

www.mdpi.com/1422-0067/26...

20.04.2025 18:17 👍 3 🔁 2 💬 0 📌 0
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Treat-to-target in SLE: is serology important? Results from an integrated analysis of five randomized clinical trials of belimumab AbstractObjectives. DORIS remission, based on clinical activity, and lupus low disease activity state (LLDAS), which includes serological markers, are prot

🔶Treat-to-target in SLE: is serology important? Results from an integrated analysis of five randomized clinical trials of five randomized clinical trials of belimumab

🔹🔹Normal serology enhances the protection of DORIS and LLDAS against severe and renal SLE flares

academic.oup.com/rheumatology...

10.03.2025 20:50 👍 2 🔁 1 💬 0 📌 0
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It has been a great pleasure to present our preliminary results on the role of HLA DQ2/DQ8 in the pathogenesis of idiopathic encephalitis, myelitis, and optic neuritis at #ACTRIMS2025 🧠 #Neurology @UNIEMTGirona

03.03.2025 23:04 👍 2 🔁 0 💬 0 📌 0
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Treatment guidelines for idiopathic inflammatory myopathies in adults: a comparative review Abstract. Myositis, or idiopathic inflammatory myopathy, encompasses a group of autoimmune diseases with broad-spectrum clinical presentations, with a comm

Treatment guidelines for idiopathic inflammatory myopathies in adults: a comparative review

#myopathies

academic.oup.com/rheumatology...

01.03.2025 10:40 👍 1 🔁 1 💬 0 📌 0
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Conducting a real-world study of Tumor Necrosis factor-alpha inhibitors-induced Systemic Lupus Erythematosus based on the FAERS database - Scientific Reports Scientific Reports - Conducting a real-world study of Tumor Necrosis factor-alpha inhibitors-induced Systemic Lupus Erythematosus based on the FAERS database

Conducting a real-world study of Tumor Necrosis factor-alpha inhibitors-induced Systemic Lupus Erythematosus based on the FAERS database

〰️Different TNF-α inhibitors should be continuously monitored for SLE-induced complications

www.nature.com/articles/s41...

01.03.2025 11:25 👍 2 🔁 1 💬 0 📌 0
Sexual experience and functioning in male and female patients with Sjögren’s disease: a qualitative study Objective Sjögren’s disease (SjD) can have a major impact on sexual functioning, but this topic has received limited attention in research and clinical practice. This qualitative study investigated ho...

Sexual experience and functioning in male and female patients with #Sjögren’s disease: a qualitative study

🔸 64% of women & 67% of men reported dysfunction.
🔸 Chronic stress, invisible suffering & relationship dynamics highlight the need for holistic care.

rmdopen.bmj.com/content/11/1...

25.02.2025 18:25 👍 2 🔁 1 💬 0 📌 0
Palau de la Generalitat in red #Girona

Palau de la Generalitat in red #Girona

Me, in red!

Me, in red!

Post image

Thanks @gencat #Girona for illuminating El Pati de les Magnòlies in red, joining our city to the campaign for the #WorldEncephalitisDay #RED4WED.

Some of our patients are affected by this serious condition which needs visibility to raise public awareness. 🧠🔴 #Girona #Spain

22.02.2025 22:51 👍 3 🔁 0 💬 0 📌 0
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2025 update on clinical trials in immune thrombocytopenia Summary of major novel and repurposed agents currently in clinical development for immune thrombocytopenia.

2025 update on clinical trials in immune thrombocytopenia

#ITP #Thrombocytopenia #Future #Science #ClinicalTrial

onlinelibrary.wiley.com/doi/full/10....

20.02.2025 20:38 👍 3 🔁 2 💬 0 📌 0
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Framework for implementing treat-to-target in systemic lupus erythematosus routine clinical care: Consensus statements from an international task force Implementation of Treat-to-Target (T2T) in routine clinical practice remains low in systemic lupus erythematosus (SLE). Real-world data reveal excessi…

Framework for implementing treat-to-target in systemic lupus erythematosus routine clinical care: Consensus statements from an international task force

#SLE #T2T

www.sciencedirect.com/science/arti...

17.02.2025 19:12 👍 3 🔁 1 💬 0 📌 0
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Frontiers | Assessment of clinical prognosis in autoimmune encephalitis: Girona score

The ACPE-Gi score was a reliable scale for comprehensively assessing the severity of AE and predicting the risk of disability at 3 months

#Dysautonomia and altered mental status independently predicted a poorer prognosis in patients with AE www.frontiersin.org/journals/psy...

16.02.2025 18:02 👍 3 🔁 0 💬 0 📌 0

We identified that the mean initial score was significantly higher in the group of patients who had higher mRS at 3 months compared to the other groups. In addition, autonomic symptoms and mental status impairment demonstrated to be independent risk factors to predict disability

16.02.2025 18:02 👍 0 🔁 0 💬 1 📌 0

ACPE-Gi score measured the severity in the acute phase and grouped the patients into three groups: mild (<8; 32%), moderate (8 to 15; 60%), and severe (>15; 8%). We found that the third group had a higher risk of disability compared with the first group.

16.02.2025 18:02 👍 0 🔁 0 💬 1 📌 0

Patients were strictly diagnosed with AE according to the current criteria between 1 January 2009 to 31 March 2023 at @htrueta. ACPE-Gi score included 14 items, and every item was scored from 0 to 3, depending on their severity with a sum ranging from 0 to 41.

16.02.2025 18:02 👍 0 🔁 0 💬 1 📌 0

We are excited to share our last paper on #AutoimmuneEncephalitis (AE)‼️ 🧠

The assessment of clinical prognosis in autoimmune encephalitis: Girona score (ACPE-Gi) assesses the severity in the acute phase of AE and predicting the risk of disability at 3 months, measured by mRS

16.02.2025 18:02 👍 6 🔁 0 💬 1 📌 0