Aaron and the Hoskins Lab at UW Madison

Fantastic job at #ASBMB26 by Hoskins lab undergrads presenting their posters!

Former Hoskins Lab undergrad and @uwbiochem.bsky.social biochemistry major David Beier kills it at #ASBMB2026 with his work from the Pat O'Brien lab at Michigan!

NEW PREPRINT!
How does the cytosolic iron-sulfur cluster assembly (CIA) targeting complex (CTC) recruit the FeS carrier Nar1?

check out our paper and find out!
www.biorxiv.org/content/10.6...

How timely!!!

Also thanks to @uwbiochem.bsky.social for helping to support the travel logistics for this awesome group of UW undergrads!

Awesome representation from @uwmadscience.bsky.social at the @asbmb.bsky.social #ASBMB2026 meeting in DC! #ScienceServesUsAll

RNA localization to nuclear speckles follows splicing logic Abstract. Nuclear speckles are membraneless organelles implicated in multiple RNA processing steps. In this work, we systematically characterize the sequen

Awesome new work from Jingyi Fei's lab in collaboration with Oded Regev's group.

RNA localization to nuclear speckles follows splicing logic url: academic.oup.com/nar/article/...

I was on Capitol Hill today with @asbmb.bsky.social urging lawmakers to support strong federal investment in
scientific research and training. Also to support : predictable and sustained funding.
#ASBMBAdvocates #ScienceServesUsAll

Thank you to our Wisconsin senators and representatives staffs for meeting with us! #ASBMBAdvocates

A group of more than 50 scientists pose for a photo in front of the U.S. Capitol.

Next up: 120 meetings with congressional staff on Capitol Hill to discuss why strengthening federal support for basic research is essential for U.S. competitiveness. NIH and NSF investments drive innovation!
#ASBMBAdvocates #ScienceServesUsAll
www.asbmb.org/advocacy

advocating for funding for RNA and all science with friends!

It's been a privilege to be involved with this. #FRET approaches have so many potential applications for linking in vitro studies with in cell behaviours, but lacked a consistent benchmarking molecule that works across systems: not any more! #IDRs #smFRET #singlemolecule

Big day ahead for #ASBMBAdvocates and the Ohio and Wisconsin delegation!

Thank you for visiting! It was wonderful!

Participants of the 2026 ASBMB March Hill Day listen to a presentation about the event.

ASBMB Hill Day preparation continues! This evening we welcomed more than 50 scientists from across the country who will be heading to Capitol Hill tomorrow for meetings with lawmakers to advocate on behalf of biomedical research funding! #ASBMBAdvocates

Lots of RNA biologists represented here as ASBMB heads to the Hill tomorrow to advocate for basic science -#ASBMBAdvocates

6/10 Notable finds: Asgard archaeal homologues of the Vault (MVP) complex and the Commander (COMMD) complex — two eukaryotic assemblies whose prokaryotic origins were previously unknown.
Multimer modelling predicts ring-shaped homo-oligomers in both cases. 🏛️

New preprint out!
In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...

Just arrived in DC for a busy few days speaking up for science - Friday visiting Congress with @asbmb.bsky.social and Saturday joining the @standupforscience.bsky.social rally on the Mall - before hearing and sharing some great science at the ASBMB annual meeting!

Attending #ASBMB26 & interested in postdoc training ? Stop by Booth #225 to connect w/ the Postdoctoral Affairs Office and learn about our training program and resources at UT Southwestern #postdoc
#UTSouthwestern
@asbmb.bsky.social

Therapeutic approaches for nonsense mutations in CFTR - PubMed This manuscript reviews recent developments in suppressing nonsense mutations in the CFTR gene. Nonsense mutations lead to premature termination codons (PTCs)-UAG, UGA, or UAA- that cause the…

Hot off the press from the @korostelevlab.bsky.social: Therapeutic approaches for nonsense mutations in CFTR

buff.ly/zeUPNLl #RNA #RNATherapeutics @UMassChan.bsky.social

#WashingtonDC
#StandupforScience

I feel like introns are then just the nucleus striking back....

Congratulations Danny!

I especially liked this Acknowledgement :)

We are also grateful for helpful discussions at the Single Molecule Biophysics (SMB) Conference 2025,
Aspen, CO, particularly with Steve Block, Nynke Dekker, Kier Neuman, Wesley Wong, and Michael Woodside.

New from Matt DeJong & the @pollyfordyce.bsky.social and Dunn groups at Stanford!

Engineering the mechanosensitivity of single DNA molecules via high-throughput microfluidic force spectroscopy

Matthew P. DeJong et al.

www.biorxiv.org/content/10.6...

RNA Splicing Lab - JOIN US Are you interested in investigating basic mechanisms in splicing regulation and gene expression? Our research group was launched in September 2024 and is hosted at the Institute of Molecular Infection...

We have an open position for a #PhD student (last week to apply!) & a lab technician/TA. For more information see: www.beuschlab.org/join-us
Interested in understanding post-transcriptional regulation and how #RNA #splicing decisions are made? Then take a look or share with people who might be! 🧪🧫

Same

White House stalls release of approved US science budgets The US Congress rejected sweeping cuts to science agencies. But the NIH, the NSF and NASA have had their spending slowed.

Congress rejected massive cuts to US science budgets for 2026, but much of the money still isn’t flowing to researchers.

The culprit? The White House Office of Management and Budget (OMB) is quietly slow-walking the release of funds. 🧵👇