Check out our new print that combines dense sequencing and phylodynamics to uncover a bunch of 😎 things about an understudied virus.
- Doesn't evolve for 10 months a year ✅
- Uses some mossies for maintenance, others for spread ✅
- Established in Northeast for ~300 years ✅
🦟📄 New preprint! Our first large-scale phylodynamic study of Jamestown Canyon virus (JCV) reveals how mosquito ecology shapes the evolution, persistence, and spread of this understudied arbovirus in North America.
Read it here! www.biorxiv.org/content/10.6...
Variations in annual dengue intensities are explained by temperature anomalies
Our new work led by Abbey Porzucek, @rafalpx.bsky.social, @colincarlson.bsky.social, Dan Weinberger to develop a method to compare relative dengue intensity between years and countries.
www.medrxiv.org/content/10.6...
Implications of successive blood feeding on #dengue virus inhibition by Wolbachia in Aedes aegypti mosquitoes
@entomososwin.bsky.social @mallerybreban.bsky.social @brackneylab.bsky.social @chantalvogels.bsky.social @yaleemd.bsky.social
Great to collaborate with @chantalvogels.bsky.social, Afeez Sodeinde and their team on this comprehensive work looking at dengue virus & Wolbachia interactions, making the case for considering DENV genetic diversity when implementing Wolbachia-based control interventions - key findings below! 🦠🦟
Key finding #5: Potential for dengue virus strain selection following Wolbachia interventions, with selection for few strains with a high average relative dissemination 📈
Key finding #4: Differential Wolbachia inhibition results in increased probability of dengue virus reemergence, particularly in high transmission intensity settings 💻
Key finding #3: Differential inhibition of the four dengue virus serotypes, with the least inhibition of many DENV-3 isolates in both Wolbachia strains 🧬
Key finding #2: Overall stronger inhibition by wMelM as compared to wAlbB 🦠
Key finding #1: High level of variability in dengue virus dissemination ranging from 0-100%, even in the absence of Wolbachia 🦟
We tested inhibition of 60 dengue virus isolates by two Wolbachia strains (wAlbB and wMelM) in Aedes aegypti mosquitoes. To explore the epidemiological implications of our findings, we used our experimental data to inform stochastic transmission models.
This project was a huge collaborative effort with @mallerybreban.bsky.social @ebourgikos.bsky.social Braiya Nolan, Nicole Feriancek @isabelott.bsky.social Julian Bakker @viralverity.bsky.social @perran.bsky.social Xinyue Gu @huangat.bsky.social @hsalje.bsky.social and @nathangrubaugh.bsky.social 💪
📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
🎉✨👏 Welcome to a new academic year in the Department of Epidemiology of Microbial Diseases at the Yale School of Public Health! We’re excited to continue learning, collaborating, and advancing public health together.
Very happy to have @entomososwin.bsky.social's thesis work finally published! Becky has been having an incredible month!
parasitesandvectors.biomedcentral.com/articles/10....
At Yale School of Public Health, research starts with people.
From AI and youth mental health to national medical billing reform, this is public health with national reach. bit.ly/3J1ekY7
@meganranney.bsky.social @chantalvogels.bsky.social
Thrilled to be a part of this study on Wolbachia and multiple blood feeding. Now published!
rdcu.be/eyqaG
Our first Wolbachia paper now published in Nature Communications! 🦟 Check out Becky's thread! 👇
Excited to share our paper on viral load dynamics of West Nile virus in mosquitoes! Key findings:
1. Variation in pooled Ct values from mosquito traps reflect underlying biological and epidemiological mechanisms.
2. WNV prevalence estimates are improved by using Cts rather than +ve/-ve pool status.
Despite all the shit going on, we have to celebrate our victories. New publication with @entomososwin.bsky.social and @vectorimmunity.bsky.social showing that hemocytes play a central role in disseminating flaviviruses to secondary tissues potentially functioning as a Trojan Horse(TBD)
rdcu.be/euj4g
What @edmhill.bsky.social said!!!👇
Come and join the @mossi-lab.bsky.social group! We have a postdoc position available on Wolbachia and Anopheles interactions.
app.vacancy-filler.co.uk/salescrm/Car...
🥳📢 Student Spotlight Alert!
Afeez Sodeinde, a PhD student in the Vogels and Grubaugh Labs, studies how dengue evolves and how Wolbachia impacts the virus. His work shows that we need tailored vector control strategies, not one-size-fits-all.
👉 Learn more here: medicine.yale.edu/news-article...
🥳📢 Student Spotlight Alert!
Meet Nicole Feriancek, a PhD student in the Vogels and Grubaugh Labs, sequencing over 3,000 West Nile virus samples in Connecticut. Her work tracks how the virus spreads and evolves across the state.
👉 Learn more here: medicine.yale.edu/news-article...
Absolutely thrilled to announce the launch of ARTIC2 - a £5.5M 5 year project funded by @wellcometrust.bsky.social to build on the ARTIC approach of low-cost, globally accessible genome sequencing for surveillance of outbreaks, epidemics and endemic diseases: www.birmingham.ac.uk/news/2025/am...
Mosquito larvae saying "Join Us!"
The Sorrells Lab is hiring a recent college graduate interested in neurobiology of mosquitoes! The position is ideal for someone interested in gaining skills for graduate school. Apply here: apply.interfolio.com/164849
🦟 "Effect of #chikungunya, #Mayaro and #Una #virus coinfection on #vector competence of #Aedes aegypti #mosquitoes" by Tessa Visser, @chantalvogels.bsky.social et al.
www.sciencedirect.com/science/arti...
In Connecticut -
NIH FUNDING:
$770M
JOBS SUPPORTED:
6609
ECONOMIC ACTIVITY SUPPORTED:
$1.68B
Great collaboration with: Braiya Nolan, Afeez Sodeinde, @isabelott.bsky.social, @perran.bsky.social, Xinyue Gu, @nathangrubaugh.bsky.social, Alex Perkins, and @brackneylab.bsky.social 🙌
📢New preprint! We studied the impact of successive feeding on inhibition of dengue virus by Wolbachia
Key finding: mosquito feeding behavior matters, but Wolbachia remains effective🦟🦠
Study led by @entomososwin.bsky.social and Mallery Breban
www.biorxiv.org/content/10.1...
