Andy Chetwynd

Perspectives of stakeholders on running ‘Pill School’ in community settings: a survey based study AbstractObjectives. Liquid formulations are the most widely used pharmaceutical forms among children but may not be the most appropriate. ‘Pill School’ met

Getting children to learn to swallow tablets is a fantastically useful life skill. What about doing this in a community setting?

@liverpooluni.bsky.social @alderhey.nhs.uk @newcastleuni.bsky.social @greatormondst.bsky.social @ucl.ac.uk @ljmuofficial.bsky.social

academic.oup.com/ijpp/advance...

Better than my 30 min stopover in Amsterdam....

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry This work challenges a major assumption in cell biology by showing that lipid bilayers can have drastically different phospholipid abundances between their two leaflets. This lipid abundance asymmetry...

Groundbreaking study in Cell from @leventallab.bsky.social: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes — major implications for how this membrane works. A #lipidtime must-read! www.cell.com/cell/abstrac...

We are #hiring!
*Research Data Steward*
Support the work of Cystic Fibrosis Innovation Hubs by maintaining integrity & quality of datasets, optimising workflows, and supporting #FAIR. Work within the @cbflivuni.bsky.social. More information here: shorturl.at/v3P30

#datamanagement #jobs

RNA-binding proteins and glycoRNAs form domains on the cell surface for cell-penetrating peptide entry Mammalian cells present RNA-binding proteins on the cell surface that form clustered domains containing glycoRNAs.

Excited to share the work of Jonathan Perr where he uncovered a surprisingly common feature of cell surfaces - the presentation and clustering of RNA binding proteins with #glycoRNA.

Critically support by #NIH @cp-cell.bsky.social www.cell.com/cell/abstrac...

Glycocalyx dysregulation impairs blood–brain barrier in ageing and disease - Nature Disruption of mucin-domain glycoprotein expression and function in the endothelial glycocalyx are associated with ageing and Alzheimer’s disease, leading to dysregulated blood–brain barrier function.

Happy to share this new #glycotime work with collaborator Tony Wyss-Coray, led by grad student Sophia Shi, mucin loss at the BBB is associated with aging and cognitive decline, can be reversed by restoration with with gene therapy. Aging is a mucinopathy!

www.nature.com/articles/s41...

Infographic stating 'Think kidney disease is just bad lifestyle choices?' in bold black text on a yellow background.

Promotional image featuring a burger against a yellow background with the text "Don't Kid Yourself" and the hashtag "#KidneysMatter" at the bottom.

The #WorldKidneyDay campaign and plans are now live!

This year, we're excited to launch a new campaign called 'Don't Kid Yourself.' It's all about challenging the myths about kidney disease and shedding light on the true facts.

Find out more and get involved: www.worldkidneyday.co.uk

For #WorldKidneyDay 2025, we have a new campaign, Don't Kid Yourself. It challenges the myths about kidney disease & highlights the facts.

Take this myth 👇 There are many reasons why someone gets kidney disease, it’s not just lifestyle. Read more here > worldkidney.day.co.uk

🧵 Earlier this month, the LifeArc-KRUK Centre for Rare Diseases held a successful international workshop at the Child Health Institute in the Park campus to design a clinical trial for patients with the inflammatory disease, IgA vasculitis (1/2)

In Early-Phase Pancreatic Cancer Clinical Trial, Investigational mRNA Vaccine Induces Sustained Immune Activity in Small Patient Group Learn how MSK researchers are deploying mRNA vaccines against pancreatic cancer.

An #NIH-funded research team has developed an mRNA vaccine to treat pancreatic cancer. Results from the clinical trial were published this week in Nature.

#pancreas #cancer #mRNA #vaccine #medsky #science #medicine #bluesky

Swift Universal Glycan Acquisition (SUGA) Enables Quantitative Glycan Profiling across Diverse Sample Types The ability to rapidly analyze complex mixtures of glycans derived from glycoproteins is important, but techniques are often laborious and require multiple glycan derivatization steps. Here, we descri...

Our new paper in print describes a new approach: release and analysis of N-glycans in less than 24 hours. A perfect approach for those that are glycan-curious as it does not require changing any of your proteomics buffers! 1/5
#glycotime #teammassspec
pubs.acs.org/doi/10.1021/...

Event alert! Join us for our Showcase Event at the Institute in the Park, Alder Hey Children’s Hospital on the 22nd March 2025!

9:30 AM - 4:00 PM
Details below!

#EATCShowcase #PaediatricResearch #MakingADifference #JoinUs
@alderhey.nhs.uk

@livunihls.bsky.social

@livuniresearch.bsky.social