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Rui Gonçalo Martinho

@martinholab

Our AIM is to understand the way germ cells segregate from the soma and differentiate into functional gametes.

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Latest posts by Rui Gonçalo Martinho @martinholab

The concept of nation and patriotism was mostly developed in XVIII after the french revolution in order for people to obey the new rulers and order. Hence, is this quote in general terms an oxymoron? (Mark Twain, obviously, tries to bypass it by focusing in loyalty to values and morality)

31.12.2025 12:38 👍 0 🔁 0 💬 0 📌 0

Any suggestion for a particularly good anti-H3K4me3 antibody for immunostaining in Drosophila? Lately we have been using AB8580 (rabbit) that works well (i need to double check the batch number), but it is a bit dirty (punctuated staining in cytoplasm). Thanks!!!!

15.12.2025 12:45 👍 1 🔁 0 💬 0 📌 0
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A 'toaster with a lens': The story behind the first handheld digital camera In 1975, a young engineer in the company that made Kodak film took the first picture on a handheld digital camera. Photography would never be the same again.

“Part of what happens with a lot of this stuff is it's sort of like being too early to the party," says Gustavson. "Because of their [Eastman Kodak's] research labs and innovative nature, they tended to create things that, were ahead of the curve, not behind it." www.bbc.com/future/artic...

09.12.2025 10:40 👍 2 🔁 0 💬 0 📌 0

Is there any Drosophila species known to naturally specify more than one oocyte per egg chamber? I’ve been looking through the literature but haven’t found any exceptions. Does an oddball species exist, or is the ‘one-oocyte-per-cyst’ rule truly universal across the genus?

28.11.2025 12:19 👍 2 🔁 0 💬 0 📌 0
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From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism | PNAS Experimental organisms such as the nematode Caenorhabditis elegans are fundamental to biological discovery. The success of C. elegans research has ...

C. elegans researchers were early adopters of open science: "The development of common resources and the belief that research findings and mutant strains should be freely shared has propelled worm research to the forefront"
www.pnas.org/doi/10.1073/...

28.11.2025 08:00 👍 21 🔁 13 💬 1 📌 1

6. Provide references, the more up to date the better.

20.11.2025 14:24 👍 0 🔁 0 💬 0 📌 0

4. Offer alternative perspectives. How else might this idea be framed, interpreted, or challenged? 5. Prioritize truth over agreement. If I am wrong or my logic is weak, I need to know. Correct me clearly and explain why.

20.11.2025 14:23 👍 0 🔁 0 💬 1 📌 0

2. Provide counterpoints. What would an intelligent, well-informed skeptic say in response? 3. Test my reasoning. Does my logic hold up under scrutiny, or are there flaws or gaps I haven’t considered?

20.11.2025 14:23 👍 0 🔁 0 💬 1 📌 0

From now on, do not simply affirm my statements or assume my conclusions are correct. Your goal is to be an intellectual sparring partner, not just an agreeable assistant. Every time I present an idea, do the following: 1. Analyze my assumptions. What am I taking for granted that might not be true?

20.11.2025 14:22 👍 0 🔁 0 💬 1 📌 0
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🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social

www.cell.com/cell/fulltex...

If you want to know more, read the 🧵 below:

14.11.2025 16:08 👍 111 🔁 41 💬 1 📌 6
Brandeis University, Biology Department Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US

TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961

22.10.2025 23:28 👍 86 🔁 102 💬 1 📌 3
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🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️
🔗 hhmi.news/4kSZjou

23.07.2025 15:18 👍 101 🔁 22 💬 4 📌 3
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Most migratory birds are gone but its still a gorgeous place do visit - Boquilobo Bog Natural Reserve.

09.11.2025 11:45 👍 1 🔁 0 💬 0 📌 0
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Not today, parasitic #wasps!✋🚫

#Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵

This provides a physical defense against #parasitic wasp oviposition🛡️

www.science.org/doi/10.1126/...

22.10.2025 17:12 👍 12 🔁 6 💬 0 📌 0
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Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...

06.10.2025 18:09 👍 37 🔁 34 💬 2 📌 1
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Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...

02.10.2025 14:24 👍 24 🔁 15 💬 1 📌 2
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#FossilFriday ‘Black Beauty’, one of the smallest-known specimens of Tyrannosaurus rex, displayed at The Royal Tyrell Museum in Calgary, Alberta.
wp.me/p3ihHu-1MX

03.10.2025 21:51 👍 76 🔁 23 💬 4 📌 1

Quick Drosophila question: I’m planning to integrate a construct on the second chromosome but would like to avoid the attP40 landing site. Any suggestion for a good alternative attP site on chromosome II? It’s for a skeletal-muscle–related project.
Thanks! 🙂
Rui

30.09.2025 18:34 👍 3 🔁 5 💬 1 📌 1
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Linear covariation between germline and somatic mutation rates across ciliates and mammals Wang et al. estimate the somatic mutation rate in a ciliate, which contains germline and somatic genomes in the same cell. They discover a linear correlation between per-year germline and somatic muta...

www.cell.com/current-biol...

26.09.2025 17:59 👍 2 🔁 0 💬 1 📌 0
Nautiloids (pictured)—a lineage of ancient, externally shelled cephalopods—once dominated our oceans, but today, these living fossils are threatened and in need of protection from over-exploitation.

Nautiloids (pictured)—a lineage of ancient, externally shelled cephalopods—once dominated our oceans, but today, these living fossils are threatened and in need of protection from over-exploitation.

Our latest issue is out!👇
www.cell.com/current-biol...

On the cover: Nautilus ≈ 🐙+🐚

(Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )

22.09.2025 17:28 👍 41 🔁 7 💬 0 📌 2
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Epigenetic relay: Polycomb-directed DNA methylation in mammalian development In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

15.09.2025 19:03 👍 91 🔁 35 💬 3 📌 2

“Proposals by *** outgoing *** country”… ?! We need feedback from someone that really knows about this topic :)

14.09.2025 16:41 👍 1 🔁 0 💬 1 📌 0
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Chart from last year... No big change in % of US applicants, or? . marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...

14.09.2025 13:49 👍 2 🔁 2 💬 1 📌 0

no - because this would have reduced the % of candidates from the US, right?

14.09.2025 15:28 👍 0 🔁 0 💬 1 📌 0

📰 New paper alert!

In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells.

The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...

09.09.2025 08:57 👍 22 🔁 9 💬 0 📌 2

is there data supporting your statement for this call? thanks :)

14.09.2025 11:25 👍 1 🔁 0 💬 1 📌 0
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is the US percentage for outgoing country of applicants significantly higher than last year?

14.09.2025 11:21 👍 2 🔁 0 💬 2 📌 0
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is the US percentage for outgoing country of applicants significantly higher than last year?

14.09.2025 11:20 👍 2 🔁 0 💬 1 📌 0
This is figure 2, which shows M. ibericus queens lay males from two different species.

This is figure 2, which shows M. ibericus queens lay males from two different species.

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

13.09.2025 01:13 👍 35 🔁 12 💬 3 📌 1
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Microtubules in Asgard archaea Discovery of heterodimeric, microtubule-forming tubulins in Asgard archaea, the closest known relatives of eukaryotes, reveals snapshots of microtubule evolution.

Microtubules in Asgard archaea (h/t @lanzen.bsky.social) www.cell.com/cell/fulltex... #jcampubs

11.09.2025 16:04 👍 30 🔁 10 💬 1 📌 2