Cancer Progression and Metastasis Lab

We;re hiring Junior Group Leaders! 🔬✨
We’re looking for researchers in immunology, chemical biology, AI in biology, or protein design to launch their own independent groups in our collaborative, international environment.

www.nki.nl/news-events/...

3D microtumors could revolutionize treatment decisions Chemotherapy is often a central component of treatment for advanced colorectal cancer. However, not every therapy is equally effective for every patient. Researchers from the German Cancer Research Ce...

Researchers from the DKFZ, HI-STEM stem cell institute and the biotech company Xilis in Utrecht, Netherlands, have developed a new method for selecting the most effective drug for advanced colorectal cancer before treatment begins. The method is based on tiny 3D tumor models.
t1p.de/c1gdx

Assistant Professor (Tenure Track) of Computational Immunology

join our faculty at D-BSSE, ETHZ in Basel, Switzerland! New assistant prof position (tenure-track) in computational immunology, please share or apply. ethz.ch/en/the-eth-z...

Unveiling the molecular and immunological drivers of antibody–drug conjugates in cancer treatment - Nature Reviews Cancer Antibody–drug conjugates are rapidly expanding both in the clinical treatment of cancer and in preclinical development. In this Review, Zippelius et al. highlight the molecular interactions and immune system effects of these sophisticated drugs that drive their efficacy and toxicity.

🥳And coming it at number 1🥁🥁🥁....
Our 1st most downloaded #REVIEW in 2025:

Unveiling the molecular and immunological drivers of antibody–drug conjugates in cancer treatment

#ADCs #antibodydrugconjugates @NatResCancer
#NRCtop10of2025

Inferring cancer type-specific patterns of metastatic spread using Metient - Nature Methods Metient is a statistical framework that infers patterns of metastatic spread and reconstructs cancer migration histories.

In a new paper, we introduce Metient, a new method to reconstruct the migration history of metastatic clones, and learn cancer-type specific patterns of metastatic spread, from bulk or single-cell sequencing data.

www.nature.com/articles/s41...

Tenure Track Professorship (W1 with Tenure Track to W3) in “Molecular Biology" (f/m/d) - Heidelberg job with Universität Heidelberg | 12850668 The Center for Molecular Biology of Heidelberg University (ZMBH) and the Faculty of Biosciences invite applications for a   Tenure Track Professors...

We invite applications for a Tenure Track Professorship (W1->W3) in Molecular Biology @ZMBH. We are looking for excellent postdocs, ready to start their own research group. Feel free to spread the news by reposting.
Applications can be filed until January 18th.

www.nature.com/naturecareer...

Vielen Dank für den Besuch!
#ForschenfüreinLebenohneKrebs

8e Formation SUNRiSE : 2 & 3 mars 2026! Venez vous former aux technologies récentes pour étudier les cellules souches cancéreuses et la plasticité tumorale auprès d'experts dans le domaine! Informations ici: www.sunrise-network.fr/fr/event/7e-...

by William Cross, Salpie Nowinski, George Cresswell, Maximilian Mossner, Abhirup Banerjee, Bingxin Lu, Andrea Sottoriva, @trevorgraham.bsky.social, et al. @cec-icr.bsky.social @icr.ac.uk @humantechnopole.bsky.social

Congrats Daniel🎉amazing and well deserved recognition!!

📌 This Friday at #IRBBarcelona: plenary #seminar with Dr. Rocío Sotillo, from the DKFZ German Cancer Research Center (@dkfz.bsky.social). 

Host: Dr. Lluís Ribas

🔗 Register here: https://shorturl.at/tY30N

#IRBBarcelona #CancerResearch #Seminar

🧪

Postdoctoral Training Fellow - Genomics and Evolutionary Dynimcs in Sutton | The Institute of Cancer Research View details and apply for this Postdoctoral Training Fellow - Genomics and Evolutionary Dynimcs vacancy in Sutton. Salary: Dependent on relevant Postdoctoral experience. Durati...

Open postdoc position in our lab @icr.ac.uk to develop a cfDNA test for #early detection of colorectal #cancer in inflammatory bowel disease #IBD:
jobs.icr.ac.uk/vacancies/14...

It's bench-to-bedside research, translating biology of pre-cancer evolution.

Funded by @bowelcanceruk.bsky.social

Register for our next ECLC webinar by Aeson Chang, PhD on 'Breast cancer got the nerves to resist chemotherapy' - January 15th, 2026 - USA: 5:00 PM EST | Europe: 11:00 PM CET | January 16th, Australia: 09:00 AM AEDT - bit.ly/44APSVI

With the start of our new study trying to find causes of bowel cancer in young people hitting the headlines today: www.bbc.co.uk/news/article... I'm so glad to see bold efforts to raise awareness, like this giant 5x3m poster on the Croydon station platform I pass by on my to the lab each day

We are hiring! Professor of Epithelial Stem Cell Biology & Cancer (Ref 189213) - Closing Date 7th Jan 2026 www.jobs.gla.ac.uk/job/professo... 🔬

We're looking for a Research Assistant / Senior Research Assistant to join our team. If you're interested in studying the extracellular matrix and tumour microenvironment in cancer, then get in touch. Applications will be reviewed on a rolling basis.

garvan.wd3.myworkdayjobs.com/garvan_insti...

A 4-year fully funded international PhD project in the lab in collaboration with Johan Vande Voorde.
Apply if you are interested in working on an exciting project on CRC and interorgan communication in flies and mice.

www.crukscotlandinstitute.ac.uk/cruk-si-educ...

Dreaming of a career in cancer research?
Join the International PhD Program at DKFZ - Germany’s largest biomedical research center.
Explore #cancerresearch including #cancerbiology, #bioinformatics, #epidemiology & #medicalphysics.
The Winter Selection is open now 👉 apply t1p.de/hl56b

Join us for our next meeting in Bordeaux, from the 26th to the 28th May 2026
sunrisemeeting.sciencesconf.org

🚀 Thinking about your next big career step in science?
The Int'l PhD Program at DKFZ could be a perfect fit for you.
🌍 Work in an international environment, with 500+ doctoral researchers
🔬 Do cutting-edge cancer research
Curious? Join our online info session on 20 Nov. Register here: t1p.de/ws7q3

Become our colleague! Apply for Junior Group Leader positions at @impvienna.bsky.social!

2nd MRS Early Career Research Virtual Meeting | Metastasis Research The 2025 MRS Early Career Research Virtual Meeting is a two day meeting aimed at engaging trainees and early career researchers from around the world and highlighting recent advances in metastasis research through keynote presentations, invited talks, panel discussions, and selected talks from abstracts. The meeting is organized and hosted by the Early Career Leadership Council (ECLC) of the MRS. Abstracts are being accepted for consideration for oral presentations. Abstract submission is open to graduate students, postdoctoral fellows, medical students, residents, clinical fellows, and researchers within 3 years of starting their own independent research group. Registration for this meeting is free for MRS Members!

⏰ It’s almost here!
The ECR Virtual Meeting kicks off next week, connecting ECRs shaping the future of metastasis biology.

💡 Inspiring talks from rising leaders
💬 Community-led discussions
🌍 A truly global metastasis community

🗓️ Last chance to register ➜ bit.ly/4qyxE0o
📘 Program ➜ bit.ly/4qtpVR9

Epigenetically driven and early immune evasion in colorectal cancer evolution - Nature Genetics This study nominates immune escape as an early event in colorectal cancer and shows how this can be driven through both genetic and epigenetic changes.

New @natgenet.nature.com paper from the brilliant @eszterlakatos.bsky.social presents evidence that chromatin alterations disrupt antigen presentation & neoantigens in colorectal cancer. Also that immune escape is part of the "Big Bang", at the outset of CRC growth. www.nature.com/articles/s41...

Anyone in here who applied for the @embo.org #postdoctoral #fellowship and could share some information/tips!?
I would be really grateful for any insights!!
😁🤩
@phdvoice.bsky.social #phdlife #postdoclife

🚀 Don’t miss this great event! We’ll showcase our newest work on tackling metastatic colorectal cancer 🔬✨

How immune cells become accomplices of tumors - Langener Wissenschaftspreis awarded to DKFZ researcher Daniel Kirschenbaum Daniel Kirschenbaum has developed an experimental method for investigating immune responses in living organisms with high temporal resolution. The technique enabled him and his colleagues to reconstru...

Daniel Kirschenbaum has developed an experimental method for investigating immune responses in living organisms with high temporal resolution. For this he received the Langen Science Prize, worth €15,000. 👏
@pei.de @stadtlangen.bsky.social

t1p.de/d9iua

🚀 The program is LIVE!
Our ECR Virtual Meeting brings together trainees & junior PIs pushing the frontiers of metastasis research.

💡 Inspiring talks
🤝 Community-led discussion sessions
🌍 A global Metastasis Research Society

Program ➜ bit.ly/4qtpVR9
Register by Nov 18 ➜ bit.ly/4qyxE0o

TROP-2-targeted antibody-drug conjugate SHR-A1921 for advanced or metastatic solid tumors: A first-in-human phase 1 study Zhong et al. report that SHR-A1921, a novel TROP-2-targeted antibody-drug conjugate, demonstrates promising efficacy and a tolerable safety profile in heavily pretreated advanced or metastatic solid tumors, notably ovarian, lung, and breast cancers. Its favorable safety profile with reduced bone marrow toxicity supports its potential for future combination therapy strategies.

Online Now: TROP-2-targeted antibody-drug conjugate SHR-A1921 for advanced or metastatic solid tumors: A first-in-human phase 1 study

Trop2 Drug Extends Survival in EGFR-Mutated Lung Cancer Antibody-drug conjugate cut risk for death by 40% versus platinum-based chemotherapy

An antibody-drug conjugate targeting Trop2 significantly improved survival outcomes compared with platinum-based chemotherapy in pretreated patients with EGFR-mutated NSCLC, a randomized trial from China found. #esmo25 @antoniopassaro.bsky.social
www.medpagetoday.com/meetingcover...