Andrea Zingaro

Last week we brought #IRBPhDDay2025 to life at @irbbarcelona.org.

Together with other 7 brilliant fellow PhD students, we organized a full day of science, connection & community.
Proud of what we built. By PhD students, for PhD students.

Thank you to all who made it possible!

The 2nd #IRBBarcelona #PhD Day has been a great success. A huge thank you to all participants & speakers! Special congrats to our best speakers:

𝗚𝗶𝗮𝗰𝗼𝗺𝗼 𝗠𝘂𝘁𝘁𝗶-Long Talk
𝗩𝗮𝗹𝗲𝗻𝘁𝗶𝗻 𝗣𝗹𝗲𝘁𝗲𝗮 & 𝗟𝘂𝗶𝘀 𝗡𝗶𝗲𝘁𝗼 𝗕𝗮𝗿𝗿𝗮𝗱𝗼-Flash Talks
𝗞𝗮𝘂𝘀𝘁𝘂𝘃 𝗚𝗵𝗼𝘀𝗵 & 𝗠𝗮𝗿𝘁𝗶́ 𝗦𝗶𝗱𝗿𝗼 𝗜𝗻𝗴𝗹𝗲́𝘀-Short Talks
𝗚𝗶𝘂𝗹𝗶𝗮 𝗩𝗶𝗼𝗹𝗮-Poster Session

🤗Here are some highlights from this #OpenDayIRB25 morning with families!
🔎Discoveries, experiences, and smiles from the little ones during the science workshops, the escape room, and the lab
tours.
We also danced a lot during the #RadioPAati concert by Amanda Álvaro and @thecrabapple.bsky.social 🎶

✨ Get ready to be inspired at the #IRBBarcelona #OpenDay!

🎯 Save the date!

🗓️ Saturday, May 24
Morning = family fun 👨‍👩‍👧‍👦
Afternoon = deep science dive 🔍

Sign up here! 🔗 bit.ly/3Z1wf6b

#ScienceForEveryone

🧪

Why biotech is booming in Barcelona World-class research institutes and university hospitals, a culture of groundbreaking science and a thriving investment ecosystem make Barcelona a rising star in the life sciences industry, as these t...

"Investment in Barcelona’s biotech sector is also booming, with international investors increasingly seeing the city as a potential hotbed for therapeutic breakthroughs"

Small-molecule RNA therapeutics to target prostate cancer Kuzuoglu-Ozturk et al. showcase a therapeutic approach, “translatome therapy,” to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1α through remodeling their 5′ UTR RNA structure. Zotatifin enhances anti-androgen and radiotherapy sensitivity, highlighting a promising anti-cancer treatment.

Online Now: Kuzuoglu-Ozturk et al. showcase a therapeutic approach, “translatome therapy,” to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1α through…

🟣 On #WomensDay, we recognize the incredible women of #IRBBarcelona! Researchers, technicians, managers, and other professionals whose talent and dedication push the boundaries of knowledge.

Your work fuels discovery and paves the way for future generations of women in science.

Thank you! 🙌

#8M

Remodelling of the translatome controls diet and its impact on tumorigenesis - Nature During fasting, hepatocytes selectively remodel the translatome while global translation is downregulated, showing a new signalling property of fatty acids and that, on a ketogenic diet, treatment wit...

Excited to share that our research has been published in @nature.com
! We discovered a novel FA-induced pathway that drives selective translation via eIF4E phosphorylation, key to ketogenesis and potential cancer therapy. Read more here:

🫧🔍Key breakthrough in #autism: pivotal role of #CPEB4 condensates revealed.

💊The study opens new avenues for the development of targeted treatments for autism.

📰 Nature @natureportfolio.bsky.social

✍️ Carla Garcia-Cabau, Anna Bartomeu et al.

➡️ bit.ly/3BfEGlR

📌 DOI: 10.1038/s41586-024-08289-w