Melissa Gammons

Thanks and yes, I meant to tag @cancerresearchuk.org for funding, apologies 😅

Scientific tweetorial to follow…

Finally a massive thanks to all coauthors who aren’t on this platform but all helped get this over the line despite retirement, pregnancy/new children and surgery! It was huge endeavour.

The review process at @natcomms.nature.com was thorough and thanks to the exceptional reviewers (all 5 of them) for their in depth review which challenged us and ultimately improved the manuscript

Thanks to funding from the @wellcometrust.bsky.social, @cruk-mi.bsky.social and @mrclmb.bsky.social core support

This project spanned 7-years starting in the Bienz lab @mrclmb.bsky.social and finishing in my own lab @thecimr.bsky.social, with huge thanks to both institutes for support in administration and core facilities

Wnt signalosome assembly is governed by conformational flexibility of Axin and by the AP2 clathrin adaptor - Nature Communications Gammons et al. describe how the clustering of the Wnt receptor complex in clathrin-coated locales allows Axin and GSK3 to dock at adjacent tails of the LRP6 co-receptor to assemble a signalosome that ...

Excited to share our recent paper on the Wnt signalosome www.nature.com/articles/s41...

So many congratulations! And super excited to be lab neighbours 😀 well done x

Congrats @abelljonny.bsky.social and colleagues 👏

We loved hosting the latest cohort of students to our ISAC/M programme over half term, along with @mrc-mbu.bsky.social and St Catharine's College. What a fantastic group of young people! www.cimr.cam.ac.uk/news/inspiri...

Zebra striped ribbon pin on lanyard to raise awareness for rare disease patients.

Rare Disease Day honours 300 million extraordinary individuals worldwide. Proud of our work in Geoff Woods’ lab @thecimr.bsky.social to help patients with rare sensory disorders, and hugely grateful for their engagement in research that advances knowledge & healthcare systems to benefit us all.

Hej everyone out there! The registration for this year’s Wnt Signaling Gordon Research Seminar (GRS) and Conference (GRC) is open!
Looking forward to see the whole #WNT community with us in Maine this year!

www.grc.org/wnt-signalin...

Welcome to #2 of our 'Wnt Researcher of the Week' series where we profile an active researcher in the WntUK network!

Next up is Dr Yeon Kim, PostDoc in the @ianmcgough.bsky.social lab at the @babrahaminst.bsky.social and selected ECR speaker for #WNTUK2025

Yeon's Quickfire Q&A below 🧵1/

Early bird registration discount may have passed but #WNTUK2025 is still open for standard registration and abstract submission. Still plenty of speaker/poster slots available for all career levels and areas of Wnt signalling.

Abstract deadline Feb 1st and we are just over 8 weeks from the big day!

Great new paper from Jennifer Dickens and @profmarciniak.bsky.social lab

Welcome to Bluesky WntUK! Please follow!