Lingzhong Fan

Mapping the coupling between tract reachability and cortical geometry of the human brain - Nature Communications Li et al. introduced tract-geometry coupling (TGC) to quantify the coupling between white matter tracts and cortical geometry in the human brain, shedding light on how the brain’s wiring and shape evo...

Mapping the coupling between tract reachability and cortical geometry of the human brain www.nature.com/articles/s41...

Network Occlusion Sensitivity Analysis Identifies Regional Contributions to Brain Age Prediction A low-bias, lightweight deep learning model for brain age prediction reveals the human brain's aging process through network occlusion sensitivity analysis, identifying the thalamus's dominant role a....

Human Brain Mapping | Neuroimaging Journal | Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...

New paper out in @pnas.org

We followed cells migrating along signalling gradients in 3D, and found they collectively behave as a living droplet - a self-propelling fluid that grows.

www.pnas.org/doi/10.1073/...

Arcuate Fasciculus: Evolutionary Convergence in Marmosets and Humans The marmoset is a highly vocal platyrrhine monkey that shares key anatomical and functional features with humans, providing a unique opportunity to illuminate the phylogenetic origins of diverging con...

1/ Really excited to share our new preprint "Arcuate Fasciculus: Evolutionary Convergence in Marmosets and Humans"!
Check it out here:
www.biorxiv.org/content/10.1...

Arcuate Fasciculus: Evolutionary Convergence in Marmosets and Humans The marmoset is a highly vocal platyrrhine monkey that shares key anatomical and functional features with humans, providing a unique opportunity to illuminate the phylogenetic origins of diverging con...

Possible neural convergence found between marmosets and humans for aspects of the arcuate fasciculus, a white matter tract often seen as critical to support species-specific communicative behavior (new preprint by @lingzhongfan.bsky.social and colleagues) 🧪🧠
www.biorxiv.org/content/10.1...

Mapping the coupling between tract reachability and cortical geometry of the human brain https://www.biorxiv.org/content/10.1101/2025.03.31.646498v1

A wearable repetitive transcranial magnetic stimulation device - Nature Communications Repetitive transcranial magnetic stimulation is used to treat various neuropsychiatric but its considerable power consumption and large size limit its potential for broader utility. Here, the authors ...

anytime and anywhere, accessible to all! A wearable repetitive transcranial magnetic stimulation device www.nature.com/articles/s41...

AIRUS: a simple workflow for AI-assisted exploration of scientific data https://www.biorxiv.org/content/10.1101/2025.02.23.639768v1

Excited to present the latest from the lab out today in Cell www.cell.com/cell/fulltex.... See Thread! 1/8

This Week in The Journal Genes Determine Cortical Connectivity Heterogeneity Deying Li, Yufan Wang, Liang Ma, Yaping Wang, Luqi Cheng et al. (see article e1510242024) Genetic information guides how the neural tube develop...

This Week in The Journal | Journal of Neuroscience

Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing https://www.biorxiv.org/content/10.1101/2025.02.13.638129v1

Comparative molecular landscapes of immature neurons in the mammalian dentate gyrus across species reveal special features in humans https://www.biorxiv.org/content/10.1101/2025.02.16.638557v1

I am hiring: PhD students, postdocs, admin personnel. Email me if you know somebody that may be interested in joining us in Cologne! 👇👇

Please RT for reach! 🙏🙏

Ignoring the cerebellum is hindering progress in neuroscience Traditionally considered a motor structure, the cerebellum has been shown to play a key role in several cognitive functions. However, for decades, the cerebellum has been largely overlooked and even d...

Ignoring the cerebellum is hindering progress in neuroscience: Trends in Cognitive Sciences www.cell.com/trends/cogni...

Congratulations! Hope everything works out perfectly.

Predicting individual traits from dynamic brain activity A combination of machine-learning techniques and more traditional modeling approaches can use the unique patterns of brain activity that evolve over time to predict traits such as age and cognitive…

A combination of machine-learning techniques and more traditional modeling approaches can use the unique patterns of brain activity that evolve over time to predict traits such as age and cognitive ability.
https://elifesciences.org/digests/95125/predicting-individual-traits-from-dynamic-brain-acti…

Baby Open Brains: An Open-Source Repository of Infant Brain Segmentations Reproducibility of neuroimaging research on infant brain development remains limited due to highly variable protocols and processing approaches. Progress towards reproducible pipelines is limited by a...

www.biorxiv.org/content/10.1...

New in @theinnovation.bsky.social! The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans.
Wang et al. developed the Chimpanzee Brainnetome Atlas (ChimpBNA) using a connectivity-based parcellation framework.
doi.org/10.1016/j.xi...
#Research

Topographic Axes of Wiring Space Converge to Genetic Topography in Shaping Human Cortical Layout Genetic information is involved in the gradual emergence of cortical areas since the neural tube begins to form, shaping the heterogeneous functions of neural circuits in the human brain. Informed by ...

Congratulations to Deying Li! The work on global connectopies is now live online! Topographic Axes of Wiring Space Converge to Genetic Topography in Shaping Human Cortical Layout www.jneurosci.org/content/earl...

Topographic Axes of Wiring Space Converge to Genetic Topography in Shaping Human Cortical Layout Genetic information is involved in the gradual emergence of cortical areas since the neural tube begins to form, shaping the heterogeneous functions of neural circuits in the human brain. Informed by ...

This is a follow-up study to our previous research titled "Topographic Axes of Wiring Space Converge to Genetic Topography in Shaping Human Cortical Layout" (online soon in The Journal of Neuroscience). You can find the preprint version at the following link www.biorxiv.org/content/10.1...

Mapping Early Brain Maturation: Anatomical Substrates of Cortical Connectivity Shifts in Neonates Understanding the early development of brain connectivity is essential for unraveling the mechanisms of brain maturation. In this study, we utilized diffusion MRI data from 242 term neonates to chart ...

Mapping Early Brain Maturation: Anatomical Substrates of Cortical Connectivity Shifts in Neonates
www.biorxiv.org/content/10.1...

nbdt.scholasticahq.com/article/1278...

The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans Chimpanzees (Pan troglodytes) are one of humans' closest living relatives, making them the most directly relevant comparison point for understanding human brain evolution. Zeroing in on the differences in brain connectivity between humans and chimpanzees can provide key insights into the specific evolutionary changes that might have occurred along the human lineage. However, such comparisons are hindered by the absence of cross-species brain atlases established within the same framework. To address this gap, we developed the Chimpanzee Brainnetome Atlas (ChimpBNA) using a connectivity-based parcellation framework.

The Chimpanzee Brainnetome Atlas reveals distinct connectivity and gene expression profiles relative to humans: The Innovation
www.cell.com/the-innovati...

Architecture, constraints, and behavior | PNAS This paper aims to bridge progress in neuroscience involving sophisticated quantitative analysis of behavior, including the use of robust control, ...

PNAS

Architecture, constraints, and behavior

www.pnas.org/doi/abs/10.1...

The brain’s action-mode is created by a dedicated action-mode network (AMN) rdcu.be/d5odm. In the brain’s mode continuum, AMN sits opposite DMN’s default-mode, as yin-yang. AMN might be key in pain, apathy, Parkinson’s. New @natrevneurosci.bsky.social w/ Marc Raichle & @gordonneuro.bsky.social 🧵 ⬇️

二零二五，唯愿诸位，长歌有和，独行有灯！

Dissecting origins of wiring specificity in dense cortical connectomes

Looks hot! Generative modeling for neural networks -- trying to get insight into the wiring rules of dense connectomes.

www.biorxiv.org/content/10.1...

The songbird connectome (OSCINE-NET.ORG): structure–function organization beyond the canonical vocal control network - BMC Neuroscience Background Understanding the neural basis of behavior requires insight into how different brain systems coordinate with each other. Existing connectomes for various species have highlighted brain syst...

Very nice peoject on bird brains connectome bmcneurosci.biomedcentral.com/articles/10....

www.pnas.org/doi/10.1073/...

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