Andrea McCart

Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...

www.nejm.org/doi/full/10....

Trumpty Dumpty wanted a crown…a bedtime story written and read by John Lithgow.
Enjoy.

Opinion: Jean Chrétien: Canadians will never give up the best country in the world to join the U.S. The former prime minister says it’s time to enact a Plan B to handle Donald Trump’s outrageous threats

Jean Chretien is 91 today and he gave himself a birthday present. He told @donaldtrump.bsky.social to piss off in the Globe and Mail: www.theglobeandmail.com/opinion/arti... #Trump #cdnpoli #USPolitics #51stState #51State

Article published at Nature Communications: Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome

The study mentioned by the NIH is really important and clarifies mechanisms involving #MECFS development.
Immune system impairment differs between women and men.
Viral Infection->Immune dysfunction->Reduced Brain activity->Motor Deconditioning. It is not fatigue.
www.nature.com/articles/s41...

If there is an earthquake today it may be due to Drs Salk and Sabin simultaneously rolling over in their graves #MedSky #SurgSky #Science

Covid Can Raise the Risk of Heart Problems for Years People who had severe infections are especially vulnerable.

For years, some of us have fought back against terrible misinformation that somehow attributed Covid vaccines to a big risk of heart problems.

It’s always been Covid infection, not the Covid vaccine.

Yet another study revealing the truth:

www.nytimes.com/2024/11/22/w...

#medsky

The Quality of Evidence Supporting Clinical Practice Guidelines in General Surgery This meta-analysis assesses the strength and quality of clinical recommendations in practice guidelines published by professional societies.

Evidence is too often thin in general surgery: a call to generate more & better science to support clinical decisionmaking from @ucsfsurgery.bsky.social authors! @ucsfhealth.bsky.social @ucsfcancer.bsky.social @hannahdeckermd.bsky.social #SurgSky #MedSky jamanetwork.com/journals/jam...

For next time a patient with new cancer diagnosis asks "what can I do?"

Finally some evidence to answer:
🛑Stop smoking

⤴️median OS by 1.8 yrs with cessation within 6 months

Love data that can change what we do immediately in clinic! 😀

tinyurl.com/etwcd4yv

#MedSky #SurgSky #HPBSky

📣 Friendly reminder to all the surgeons on #surgsky #medsky — @amcollsurgeons.bsky.social released surgical ergonomics recommendations on how to optimize body posture and OR layout to mitigate risk of work-related MSK disorders — check them out!

#surgicalergonomics

The way the country feels like it’s about to be run…through a surgeon’s lens. #MedSky #SurgSky

Wishing a happy #WorldDiabetesDay to all my fellow beta-cell-challenged people & those who help them. May your lines be level & may we all have easy access to what helps us stay alive & well. #T1D #insulin4all

In case it’s useful to anyone, I wrote this last year: holly.witteman.ca/management-l...

We’re Not Testing Enough for Bird Flu The most important tool in our arsenal is widespread testing, write Janika Schmitt and Michael Mina. We're not doing enough of it.

The more severe H5 BirdFlu virus infection in Canada has mutations that may have arose in a single patient

Worryingly these enable more efficient use of human sialic acid receptors by the virus

This is the scary scenario we fear

There is much we can do!

A thread

time.com/6976402/bird...

RFK Jr. is now an extinction-level threat to federal public health programs and science-based health policy | Science-Based Medicine Donald Trump said that he would let Robert F. Kennedy, Jr. "go wild" on healthcare. If that happens, say goodbye to science-based federal health policy.

As the great David Gorski put it: RFK Jr. is now an extinction-level threat to federal public health programs and science-based health policy

sciencebasedmedicine.org/rfk-jr-is-no...

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"[AIDS] is not being caused by a virus. It's not a virus... These people are dying because of 'poppers'... they were people who were part of a gay lifestyle... "

"This is not a viral disease, but it's a disease that is environmental."

- HHS Secretary Nominee RFK Jr

/1

This is the rallying call that I've needed to hear since November 6th. From Roxane Gay in today's New York Times www.nytimes.com/2024/11/17/o...

Surge in worldwide measles cases driven by lack of vaccine coverage, WHO says The WHO and CDC say there were about 10.3 million cases of measles last year, up 20 percent from 2022. Children are especially susceptible to complications.

10.3 million cases of measles occurred worldwide last year, up 20% from 2022, primarily because of inadequate immunization coverage.
The disease resulted in 107,500 deaths last year, mostly killing children under 5!!!!
There are no upsides to shunning vaccines.
www.washingtonpost.com/health/2024/...

Vaccine shows promise against aggressive breast cancer | WashU Medicine Clinical trial targeted recurrence of hard-to-treat triple-negative breast cancer

Good morning, Bluesky. Today’s #GoodMorningNews: a trial at Washington University’s school of medicine has shown great results for a vaccine that would prevent recurrence for a particularly aggressive form of breast cancer. It’s a small trial, but 3 years later 16/18 participants remain cancer free

Earnest post, but: a thing I like here is it’s okay to have moments of happiness in public without being broadly scolded, and I believe that sustaining this kind of humanity will be very important as we resist fascism.

We have to sustain each other. Making joy isn’t denial, it’s how we will survive