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Jessica Little

@jessicalittlemd

Transplant Infectious Diseases Physician @ Brigham and Women’s Hospital + Dana-Farber Cancer Institute | Instructor @ Harvard Medical School || heme/onc ID | clinical trials | antimicrobial stewardship ||

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Latest posts by Jessica Little @jessicalittlemd

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New webinar on fungal diagnostics!

Link in next post

19.01.2026 13:10 👍 2 🔁 4 💬 2 📌 0
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Controversial US study on hepatitis B vaccines in Africa is cancelled $1.6m project drew outrage over ethical questions about withholding vaccines proven to prevent disease

BREAKING: The controversial hepatitis B vaccine trial in Guinea-Bissau has been *cancelled,* I can now report. A senior official with Africa CDC confirmed the cancellation and said GB officials are working to make sure any research is conducted ethically:
www.theguardian.com/us-news/2026...

15.01.2026 15:28 👍 730 🔁 285 💬 9 📌 85

The full protocol of the study in Guinea Bissau provides no reassurance. If anything is spells out just how insanely unethical the planned study is. The PI who wrote the protocol tried to defend the indefensible by writing to me directly. I responded publicly.
Read 👇
substack.com/@bktitanji/n...

15.01.2026 14:10 👍 138 🔁 58 💬 10 📌 9
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Scoop: The leaked protocol of the CDC-funded Hepatitis B vaccine trial in Guinea-Bissau. “This is another Tuskegee.” The protocol reveals that the trial will withhold the Hepatitis B birth dose from thousands—without placebos, without universal maternal screening, and with endpoints critics call indefensible.

The leaked protocol of the CDC-funded Hepatitis B vaccine trial in Guinea-Bissau. “This is another Tuskegee.”

It is worse because it is clear upfront that this is unethical and poorly designed.
@insidemedicine.skystack.xyz

open.substack.com/pub/insideme...

15.01.2026 13:06 👍 4 🔁 1 💬 0 📌 1
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Invasive Fungal Disease in Transplantation: Prevention in a Shifting Landscape | Contagion Live Invasive fungal diseases remain a major cause of morbidity and mortality in patients undergoing transplant, with shifting epidemiology, emerging resistance, and geographic variation underscoring the u...

Quick read on #fungal infections in #transplant patients. @jessicalittlemd.bsky.social rocks! #IDSky #MedSky www.contagionlive.com/view/invasiv...

14.01.2026 22:18 👍 11 🔁 6 💬 0 📌 0
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Combination Therapy for Protracted COVID-19: When More is More

Combination Therapy for Protracted COVID-19: When More is More

✅ Just Accepted
#IDSky

18.07.2025 18:58 👍 4 🔁 2 💬 1 📌 0
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Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy Immunocompromised patients remain at risk for protracted SARS-CoV-2 infections with persistent viral shedding that could pose a wider public health risk.

Protracted SARS-CoV-2 Infection in B-cell Depleted Patients: Immunologic and Viral Characteristics and Response to Dual and Extended Antiviral Therapy

✅ Just Accepted
⭐ Editor's Choice
#IDSky

19.07.2025 12:41 👍 4 🔁 4 💬 0 📌 0
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Advisory Committee on Immunization Practices at a Crossroads In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy, includin...

Important read from all 17 highly qualified ACIP members who recently dismissed - read and share widely

jamanetwork.com/journals/jam...

17.06.2025 04:01 👍 77 🔁 41 💬 0 📌 3
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Advisory Committee on Immunization Practices at a Crossroads In this Viewpoint, former members of the Advisory Committee on Immunization Practices (ACIP) caution that the sudden change in the ACIP may reverse the achievements of US immunization policy, includin...

Very proud of the 17 ACIP members for publishing this jamanetwork.com/journals/jam...

16.06.2025 19:03 👍 15 🔁 8 💬 0 📌 3
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One Hundred Days, Incalculable Losses Emily J Erbelding, M.D., M.P.H; One Hundred Days, Incalculable Losses, The Journal of Infectious Diseases, , jiaf317, https://doi.org/10.1093/infdis/jiaf31

"The story of the negative impact on the future of infectious disease research will only become part of public discourse if scientists speak up loudly"

A must read.

One Hundred Days, Incalculable Loses @jidjournal.bsky.social

Emily Erbelding, MD - NIAID/DMD

academic.oup.com/jid/advance-...

12.06.2025 16:12 👍 75 🔁 39 💬 2 📌 4
Leading Life Science Organizations: Unlawful Grant Terminations Pose Grave Threat to America’s Innovation Pipeline - ASCB Amicus Brief Filed in Support of Suit Calling for Immediate Funding Restoration WASHINGTON, DC – Four leading life science organizations, including the ASCB, filed an amicus brief today asking the cou...

Unlawful grant terminations are harming young scientists and threatening innovation. ASCB joins leaders calling for immediate funding restoration.

www.ascb.org/society-news...

02.05.2025 19:03 👍 143 🔁 71 💬 2 📌 7
Four Leading Science Organizations File Amicus Brief Supporting Funding Restoration ASM joined leading life science organizations in an amicus brief filed in support of a suit calling for immediate funding restoration.

Together with leading science organizations, ASM filed an amicus brief calling for immediate restoration of NIH grants supporting early-career scientists. Read the press release: asm.org/press-releas...

02.05.2025 20:41 👍 148 🔁 57 💬 2 📌 2

🚨UPDATE: Rümeysa Öztürk has now suffered three separate asthma attacks while in DHS custody.

She has not received her required asthma medications—a violation of her fundamental right to medical care.

This is cruelty, it is neglect, and it is a damning moral and legal failure.

03.04.2025 23:34 👍 13648 🔁 5807 💬 224 📌 240

ASH decries HHS restructuring and CDC layoffs. The Blood Disorders Division addresses SCD, thrombosis, hemophilia, thalassemia, and more. Millions' health is at stake; ASH urges immediate action.

#Fight4Hematology #HemeSky #MedSky

01.04.2025 21:02 👍 82 🔁 37 💬 2 📌 2
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'Bloodbath' at NIH and Elsewhere at HHS Begins Splinter is your home for news and opinions that challenge power in our political and economic system that's becoming more unhinged each and every day.

Today our nation's world leadership in science begins a slow death. We lose all the potential innovation, jobs, medicines, novel treatments, & science discoveries to save and improve lives. CDC & NIH will be a shell of themselves.

Will hurt for decades.

www.splinter.com/bloodbath-at...

01.04.2025 16:22 👍 2 🔁 3 💬 0 📌 0
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‘It’s a bloodbath’: Massive wave of job cuts began at US health agencies | CNN A massive wave of job cuts began at US health agencies early Tuesday, with some employees receiving early morning emails that their jobs were eliminated and some unable to access the building when the...

A sad day for science & public health www.cnn.com/2025/04/01/h...

01.04.2025 14:34 👍 68 🔁 27 💬 0 📌 3
SCiMaP

Just in NIH grants, It looks like beautiful Iowa City, home of the U of Iowa, will lose $71m in funding. That's almost $1k per resident. And that's before all the other cuts to SSA, FDA, etc.

Anyone in Iowa City that can offer more insight?
scienceimpacts.org
H/T to Prathima !

29.03.2025 18:29 👍 18934 🔁 5624 💬 887 📌 255
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We are committed to supporting #CancerCare providers and patients who may be affected by public health issues. A listing of measles and vaccination resources can be found on our website and will continue to be updated: asco.org/news-initiat...

27.03.2025 14:21 👍 13 🔁 10 💬 0 📌 0
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Some measles patients in West Texas show signs of vitamin A toxicity, doctors say, raising concerns about misinformation | CNN Doctors treating people hospitalized as part of a measles outbreak in Texas and New Mexico have also found themselves facing another problem: vitamin A toxicity.

Irresponsible public health leadership is dangerous and it kills.
The head of DHHS routinely tries to practice medicine without a license via podcasts and TV interviews and encouraged Vitamin A as treatment for measles. This is the direct result!
www.cnn.com/2025/03/26/h....

27.03.2025 14:59 👍 128 🔁 54 💬 6 📌 3

Sure looks like it'll be a 'study' with a predetermined outcome. If this were really an open question (it is not) it would make sense to contract with one of the numerous centers with extensive experience in vaccine trials. (1/2)

26.03.2025 15:21 👍 2 🔁 2 💬 1 📌 0
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Clinical Positions in Transplant Infectious Diseases 2024-2025 University of California, Los Angeles is hiring. Apply now!

We are hiring #TxID #TxIDSky faculty at @ucla-id-fellowship.bsky.social @domucla.bsky.social - come join our dynamic and collaborative group to battle infection in sunny Los Angeles! @ast-idcop.bsky.social See link for description and please reach out with questions! recruit.apo.ucla.edu/JPF09517

23.03.2025 14:51 👍 8 🔁 7 💬 0 📌 0
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New episode out now! Get to the bottom of a nonresponding pneumonia and hear some discussions about endemic fungal disease! 🍄 Ft. @tomschmidt30.bsky.social @natebahrid.bsky.social @grthompsonmd.bsky.social

Follow @msgerc.bsky.social for more fungal learning!
#IDSky

17.03.2025 20:12 👍 10 🔁 10 💬 0 📌 1
Febrile #115: Dust to Diagnosis – with MSGERC – febrile

Loved listening to this new @febrilepodcast.bsky.social episode on endemic mycoses 🍄with @grthompsonmd.bsky.social @tomschmidt30.bsky.social @natebahrid.bsky.social @msgerc.bsky.social

febrilepodcast.com/115-dust-to-...

17.03.2025 17:16 👍 5 🔁 2 💬 0 📌 0
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115: Dust to Diagnosis - with MSGERC Febrile · Episode

Check out the new episode of @febrilepodcast.bsky.social “Dust to Diagnosis”

Great experience working with @grthompsonmd.bsky.social, @natebahrid.bsky.social, & @msgerc.bsky.social!

open.spotify.com/episode/61sB...

#IDSky
#Fungi

17.03.2025 14:44 👍 15 🔁 10 💬 2 📌 0
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20250314-TTS-EC This is "20250314-TTS-EC" by TTS on Vimeo, the home for high quality videos and the people who love them.

Looking for a comprehensive review of measles in solid organ transplantation? #TTS #TID organized a webinar that will get your prepared! It is on 🔥 @kottonnelson.bsky.social @jobadd.bsky.social
urldefense.com/v3/__https:/...

15.03.2025 15:30 👍 15 🔁 7 💬 0 📌 0
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UMass Chan rescinds admission for biomedical sciences PhD program amid funding concerns UMass Chan Medical School is rescinding admission offers to candidates for its biomedical sciences PhD program over concerns about federal funding cuts.

A troubling moment for the next generation of scientists.

UMass Chan Med School is rescinding dozens of PhD offers in biomedical sciences due to fears over federal research funding cuts.

www.nbcboston.com/news/local/u...

13.03.2025 17:13 👍 467 🔁 196 💬 18 📌 19
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Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens Measles virus infection can cause long-term damage to the immune system.

MMR is better than natural infection for many reasons > Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens #measlesoutbreak www.science.org/doi/10.1126/...

10.03.2025 21:51 👍 11 🔁 4 💬 0 📌 0

Why…

08.03.2025 15:42 👍 7 🔁 5 💬 0 📌 0
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ID physicians stand up for science to protect our patients. #IDStandsUpForScience

In honor of tomorrow's #StandUpForScience rallies, share the reason why you stand up for science with the hashtag #IDStandsUpForScience.

07.03.2025 02:01 👍 39 🔁 12 💬 0 📌 1
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Welcome! You are invited to join a webinar: Measles: A TEPHI Live Forum. After registering, you will receive a confirmation email about joining the webinar. Join us for "Measles: A TEPHI Live Forum," covering the essentials you need to know about the current measles outbreak, direct from a panel of experts: Luis Ostrosky-Zeichner, MD, physician and infect...

Join us for a webinar on #measles this Friday. Organized by #TEPHI uthealth.zoom.us/webinar/regi...

04.03.2025 21:38 👍 2 🔁 1 💬 0 📌 0