IKGbiofilms

New #sciart thread

Feel like doing a SynBio PhD in Spain? Check this offer, many fellowships available 👉🏻 lifehub.csic.es/synbio-cofund/

Broadening art–science collaboration in biotechnology: integrating design This article extends recent conversations on art–science collaboration in biotechnology to include design and biodesign. We highlight the rise of biodesign, tinkering with design, and more-than-human approaches in fostering innovative, sustainable outcomes for contemporary biotechnology, illustrating these opportunities through case studies in transdisciplinary partnership.

Online now: Broadening art–science collaboration in biotechnology: integrating design

Quantifying metabolites using structure-switching aptamers coupled to DNA sequencing - Nature Biotechnology Metabolites can be quantified using a combination of aptamers and DNA barcodes.

Metabolites can be quantified using a combination of aptamers and DNA barcodes go.nature.com/42BbXTQ
rdcu.be/eZ8BP

Bacterial metabolites induce cell wall remodeling, antifungal resistance, and immune recognition of commensal fungi Davis et al. demonstrate that common gastrointestinal bacteria secrete metabolites that induce global cell remodeling in Candida albicans. C. albicans uses the HOG cascade, a central stress pathway, t...

Bacterial metabolites induce cell wall remodeling, antifungal resistance, and immune recognition of commensal fungi

@currentbiology.bsky.social from @teresaomeara.bsky.social

E.coli vs C.albicans

www.cell.com/current-biol...

Engineered living glues secrete therapeutic proteins for treatment of inflammatory bowel disease - Nature Biotechnology Engineered bacteria sense gut bleeding and secrete repair materials.

Engineered living glues secrete therapeutic proteins for treatment of inflammatory bowel disease go.nature.com/4pJHFpL

Dominant contribution of Asgard archaea to eukaryogenesis www.nature.com/articles/s41... #jcampubs

White dried coral and the patterns that it forms while growing.

Coraled patterns
#rockintuesday #photography #coral #geometry #eastcoastkin

How medically important antimicrobials bind to the 30S ribosomal subunit in a bacterial pathogen Ribosomes translate the genetic code in mRNA to synthesize proteins in all living organisms. Decoding of mRNA occurs in the small subunit of the ribosome and is mediated by tRNA anticodons. Regions ne...

1/ Our new preprint is out on biorxiv on how antibiotics bind to bacterial 30S subunits, please repost. #ribosome #antibiotics #microsky #rnasky doi.org/10.64898/202...

Our editors pick their favorite research articles from 2025 go.nature.com/4oCK84L

Locating the missing chlorophylls f in far-red photosystem I The discovery of chlorophyll f–containing photosystems, with their long-wavelength photochemistry, represented a distinct, low-energy paradigm for oxygenic photosynthesis. Structural studies on chloro...

This week in @science.org
Structural insight into the incorporation of far-red chlorophyll f in cyanobacterial photosystem I
www.science.org/doi/10.1126/...
#cyanobacteria
#plantscience

✨New preprint!

🧵1/4 Excited to share our work on AI-guided design of minimal RNA-guided nucleases. Amazing work by @petrskopintsev.bsky.social @isabelesain.bsky.social @evandeturk.bsky.social et al!
Multi-lab collaboration @banfieldlab.bsky.social @jhdcate.bsky.social @jacobsenucla.bsky.social🧬

🔗👇

This is a super cool story - congrats!!!

New publication alert IKG lab at @asm.org : Diverse strategies of #Bacillus subtilis to avoid #amoeba #predators. Link to our publication: journals.asm.org/doi/10.1128/....
This paper follows up on our first work in @springernature.com: www.nature.com/articles/s41...

Differential coping strategies exerted by biofilm and planktonic cells of Bacillus subtilis in response to a protozoan predator | Microbiology Spectrum The human protozoan parasite Entamoeba histolytica feeds on intestinal microbiota to survive. To enhance the effectiveness of probiotics, we characterized how they respond to amoeba predators. We foun...

New manuscript with the Ankri lab @technion.bsky.social published in Microbiology Spectrum journal @asm.org: Differential coping strategies exerted by #biofilm and #planktonic cells of #Bacillus subtilis in response to a #protozoan predator | journals.asm.org/eprint/G6ZQ6...

Evolution of antivirus defense in prokaryotes, depending on the environmental virus prevalence and virome dynamics | mBio The virus-host arms race is a major component of the evolutionary process in all organisms that drove the evolution of a broad variety of immune mechanisms. In the last few years, over 200 distinct antivirus defense systems have been discovered in prokaryotes. There are two major modes of immunity acquisition: innate immune systems spread through microbial populations via HGT, whereas adaptive-type immune systems acquire immunity via direct interaction with the virus. We developed a mathematical model to explore the short-term evolution of prokaryotic immunity and showed that in stable environments with predictable viral repertoires, adaptive-type immunity is the optimal defense strategy, whereas in fluctuating environments with unpredictable virus composition, HGT dominates the immune landscape.

Evolution of antivirus defense in prokaryotes, depending on the environmental virus prevalence and virome dynamics
#microbiology #virology #virus
@asm.org
journals.asm.org/doi/10.1128/...

Rewiring microbial metabolism through post-translational switches Recent advances in post-translational regulatory tools have enabled precise and rapid control of metabolic flux in microbial cell factories. In this review, we systematically summarize current post-tr...

From @cp-trendsbiotech.bsky.social @cellpress.bsky.social #Microbial #Biotechnology Review: Rewiring microbial #metabolism through post-translational #switches: www.cell.com/trends/biote...

Multi-Omics Insights into Plant-Microbe Dysbiosis Caused by Cyanobacterial Bloom-Affected Water

www.sciencedirect.com/science/arti... #OpenAccess #MicroSky

Modulation of the Pseudomonas aeruginosa quorum sensing cascade by MexT-regulated factors | mBio Bacteria interact with both abiotic and biotic factors in their environment. Quorum sensing (QS) is one mechanism that bacteria use to communicate with other bacteria and coordinate behaviors in the p...

New lab paper!

Andrew Frando describes how MexT alters the quorum sensing cascade in P. aeruginosa. /1

With Nicole Smalley; two undergraduates, Jamal Omar and Bobby Parsek; and @dezieleric.bsky.social, @mariecg.bsky.social, and Mylène Trottier at INRS in Montreal

journals.asm.org/doi/10.1128/...

How do microbes survive the most extreme environments on Earth and what does that tell us about life beyond our planet? #FEMSMicrobes is welcoming papers on the microbiology of extreme environments and their links to astrobiology. 🦠 🌌 Submit before 31st December 2025: buff.ly/frV0k6l

Escherichia coli with a 57-codon genetic code The near-universal genetic code uses 64 codons to encode the 20 canonical amino acids and protein synthesis. Here, we designed and generated Escherichia coli with a 4-megabase synthetic genome in whic...

Escherichia coli with a 57-codon genetic code www.science.org/doi/10.1126/...

Some years ago, we discovered a modern microbialite reef under conditions resembling primitive Earth 🌋

Now we show how seasonal extremes drive microbial shifts and mineralisation, offering a window into processes that shaped Earth’s first biostructures 🪨

www.nature.com/articles/s43247-025-02764-6

But what did they publish since?

Projected climate change effects.

Producing enough food to feed more than 8 billion people is challenging. However, microbes offer powerful solutions in the form of biofertilizers and biochar, ultimately promoting crop health and boosting global food security and resilience. asm.social/2E7 #WorldFoodDay

An exciting exploration of microbial genomics and ecology, highlighted by a surprising journal recognizing the power of #Microbes. The unsung heroes of global #sustainability frameworks @natrevgenet.nature.com

Hijacking a bacterial ABC transporter for genetic code expansion - Nature Bacterial ATP-binding cassette (ABC) transporters can be utilized and engineered to transport non-canonical amino acids into Escherichia coli for highly efficient synthesis of proteins with novel func...

🚨Our paper is out! 🥳
Hijacking a bacterial ABC transporter for efficient genetic code expansion.
Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social
www.nature.com/articles/s41...

it all started years ago with a failed experiment
🧵👇 1/9

Principal coordinate analysis of the particle-associated communities that increased in the free-living fraction in response to Tween treatments (P value < 0.01). The color of the particle-associated (triangle) shapes corresponds to the Tween treatment, as indicated by the key. The crosses indicate the centroid points for each treatment. Vectors represent increased PA-OTUs with significant relationships (P value < 0.01) to the ordination axes, which are driving the differences in PA-OTU community composition between Tween treatments. Red vector labels represent E-PA-OTUs that increased significantly (P value < 0.05) in the FL fraction in response to at least one Tween treatment relative to controls.

Marine particles harbor microbial communities. However, to study them, they must be separated from the particle. How? This #AppEnvMicro article outlines an optimized method using detergents to dissociate microbes from marine particles. Get the details: asm.social/2DG

Tel Dor beach. School vacation

FEBS Press The bacterial dynamin-like protein DynA from Bacillus subtilis plays a key role in phage defense. It binds the plasma membrane through a unique paddle domain in its D1 subunit. This membrane associat....

Binding of Bacillus subtilis dynamin-like protein DynA to the bacterial membrane is essential for effective phage defense

@febsj.bsky.social from @bramkamplab.bsky.social

febs.onlinelibrary.wiley.com/doi/10.1111/...

Frontiers | Exploring Academic Ecosystems in STEM: A Way Forward Historically, ecosystems frameworks have been leveraged to understand and examine the functions of living organisms within various environments, particularly...

New Research Topic alert!

'Exploring Academic Ecosystems in STEM' is now open for submissions in Frontiers in Education. @berondam.bsky.social @beckypackard.bsky.social

Submit your manuscript summary by 11 January 2026 ➡️ www.frontiersin.org/research-top...

#Ecosystems #STEM