Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines.
www.biorxiv.org/content/10.6...
Is arginine the new cysteine?! Check out our lab's latest in collaboration with @ianseiple.bsky.social's team where we introduce ninhydrin as a selective covalent warhead and probe targeting reactive arginines.
www.biorxiv.org/content/10.6...
๐จExcellent editorial in ACS Central Sci ๐ฃ
Thank you @carolynbertozzi.bskyverified.social for your support and to @louisflwilson.bsky.social for spotting these mistakes + drafting an excellent manuscript
#CryoEM #StructuralBiology
#vidalized
ACS Central Science pubs.acs.org/doi/full/10....
Calico is hiring for roles in medicinal chemistry, process chemistry, preclinical magnetic resonance imaging, antibody engineering, toxicology #chemjobs
www.calicolabs.com/careers/
Livestream dive two. We see a strawberry squid and a sea of brittle stars: www.youtube.com/watch?v=HZLe...
Fantastic tool, thank you! I submitted to q.e.d. a grant proposal, and, notwithstanding the impressive insights and display of knowledge, itโs clear the system still cannot grasp the different requirements between articles and project proposals. It would be extremely useful to add this capability.
This one is a bit of a departure from the usual and definitely a work in progress!
We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.
Read on for details... 1/x
๐จ We have an open #postdoc position to join my new group at the University of Milan๐ฎ๐น to pioneer innovative #antiviral strategies using novel protein degradation technologies๐งฌ๐ฆ
๐ Details below
๐ฌ If you are a molecular biologist interested in viruses and new technologies, get in touch!! โ๏ธ
#hiring #TPD
RFK Jr. is upset that a recent large Danish study in Annals of Internal Medicine, conducted over 20 yrs in 1 M kids, found no association between aluminum in childhood vaccines & 50 different health conditions.
His request for the retraction was rejected.
๐งช www.reuters.com/business/hea...
We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).
And of course, it was fantastic as always to listen to Richard Henderson and Nigel Unwin
Awesome lineup for the โStructure of Bacteriorhodopsin: 50 Years Onโ symposium @mrclmb.bsky.social : Niko Grigorieff, John Rubinstein, Gebhard Schertler, Bridget Carragher, and many more.
I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs.
Plant, Bacterial, Archaeal Non-model Bioeng
Custom Lab Hardware
Turn Key Genetic Design
Please repost for reach ๐
Really cool work on diffusing structures into cryo-EM densities by Ellen Zhong et. al arxiv.org/html/2506.04...
#cryoem
๐จ We're Hiring! We're looking for a passionate and skilled EM Specialist to join our team! ๐ Application Deadline: July 9th, 2025 ๐ Learn more and apply here: careers.humantechnopole.it/o/electron-m...
Good suggestion! Keep them coming!!
Call me old fashioned (please donโt ๐) but I still value good textbooks particularly for teaching at entry level. A good amount of integration is almost always needed on a yearly basis anyway.
Hey, Iโm looking for a bachelor level textbook on Synthetic Biology (ok for students with basic molecular biology knowledge): any suggestions please?? Perhaps @atinygreencell.bsky.social ?
A Florida weatherman telling his viewers he can no longer be confident in his forecasts due to cuts to atmospheric science is the kind of resistance content Iโm here for.
Kudos, Sir.๐ฆ๏ธ
Finisce nel modo piรน inglorioso uno dei piรน grandi fallimenti politici ed economici della Repubblica.
I centri per migranti in Albania, costati 933 milioni di โฌ, a detta del Premier Rama, non possono funzionare.
Ecco cosa succede quando governi a colpi di slogan e propaganda.
David Liu @harvard.edu beautifully articulates the criticality of basic science funding for developing revolutionary therapeutics like life-saving base editors ๐
youtu.be/8YhJM6zxYDw?...
Molto ben scritto! Diffondete anche e soprattutto fuori di questa bolla.
Thank you Guido for a great seminar #UniPV #DBB_unipv ! I am glad that your are gonna be in the neighbourhood๐
Friends, if anyone is looking for an electron microscopist outside of the US, I'm listening. Open to any country, regardless of weather. Can do cryo, room temp, image anything from tissues to nanoparticles, viruses, catalysts, etc. Thanks for any lead(s).
Almost every line of this story would have been simply unbelievable a few months ago:
โPioneering cancer researcher;
โ*Arrested* at airport in Boston;
โNow indefinite ICE detention in Louisiana;
โ"Crime": not declaring some frog-embryo samples for research.
Read it.
www.nbcnews.com/news/us-news...
I wished Columbia had done the right thing, too.
Highly recommended PhD opportunity!
'(...) German research institute BioMed X is stepping in to offer a lifeline. The institute has opened a matchmaking program to align threatened NIH grants with potential new funders from the pharmaceutical industry.'
www.fiercebiotech.com/research/ger...