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DLRamamurthy

@dlramamurthy

Assistant Professor of Behavioral Neuroscience at the University of California, Riverside https://scholar.google.com/citations?user=rx0-fg8AAAAJ&hl=en

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05.09.2023
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Latest posts by DLRamamurthy @dlramamurthy

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Join us at TENSS 2026 to open black boxes, explain how things/brains work and debate the impact (or lack or it) of various new technologies on understanding of the brain and on society. tenss.ro Apply by: March 15th!

10.03.2026 01:28 πŸ‘ 16 πŸ” 17 πŸ’¬ 0 πŸ“Œ 0

Excited to introduce ScaRCaMP β€” a highly blue-light resistant red GECI. πŸ”΄

Now live on bioRxiv and marking my first PhD preprint (2nd for the Marko lab).

Would love feedback from the community!!

04.03.2026 22:23 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Attention-related modulation in the superior colliculus encodes perceptual sensitivity, but not perceptual choice Nature Communications, Published online: 28 February 2026; doi:10.1038/s41467-026-69954-4The specific contributions of different SC (superior colliculus) neuron subtypes to the diverse perceptual and behavioral aspects of attentional performance remain unclear. Here authors show that neurons in the SC support visual spatial attention by enhancing perceptual sensitivity and motor bias, without reflecting internal perceptual decisions or choice accuracy, revealing its unique role in transforming attention into action.

Attention-related modulation in the superior colliculus encodes perceptual sensitivity, but not perceptual choice @natcomms.nature.com

28.02.2026 22:52 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Neuroscience has a species problem If neuroscience is serious about building general principles of brain function, cross-species dialogue must become a core organizing principle.

Differences between species should be treated as informative constraints that refine theory, not as inconsistencies to be explained away, writes @suthanalab.bsky.social.

#neuroskyence

www.thetransmitter.org/animal-model...

19.02.2026 17:04 πŸ‘ 22 πŸ” 9 πŸ’¬ 0 πŸ“Œ 1
2026 Neurobiology of Cognition (GRS) Seminar GRC The 2026 Gordon Research Seminar on Neurobiology of Cognition (GRS) will be held in Waterville Valley, New Hampshire. Apply today to reserve your spot.

Trainees: check out the Neurobiology of Cognition Gordon Research Seminar that is taking place this summer in New Hampshire. The theme is "Cells, Circuits, and Computation".
www.grc.org/neurobiology...

17.02.2026 02:20 πŸ‘ 18 πŸ” 7 πŸ’¬ 0 πŸ“Œ 0
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Do you work or study in the fields of psychology, neuroscience, computer science, artificial intelligence, or philosophy?

What does the term 'representation' mean to you?

We invite you to participate in a brief survey on key conceptual questions across fields.

eu.surveymonkey.com/r/VX9GNXM

12.02.2026 13:39 πŸ‘ 66 πŸ” 60 πŸ’¬ 4 πŸ“Œ 3
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Duration between rewards controls the rate of behavioral and dopaminergic learning - Nature Neuroscience Cue–reward learning rate scales proportionally with the time between rewards. Consequently, learning over a fixed duration is independent of the number of trials. This challenges trial-based dopamine ...

Big if true. Anyone know if human learning curves are also (mostly) trial count independent?

www.nature.com/articles/s41...

12.02.2026 20:10 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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πŸ”¬πŸ§  Releasing the 1.0 version of #Suite2p and THE PAPER w/ @marius10p.bsky.social! Now with GPU acceleration. Want to use Suite2p but don’t have 100,000 neuron recordings? We show you how to get those with a standard 2p microscope #neuroscience #imaging #neuroAI www.biorxiv.org/content/10.6...

12.02.2026 01:32 πŸ‘ 98 πŸ” 35 πŸ’¬ 2 πŸ“Œ 2
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From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity.

Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity, writes @lmprida.bsky.social.

#neuroskyence

www.thetransmitter.org/defining-cel...

09.02.2026 15:04 πŸ‘ 21 πŸ” 15 πŸ’¬ 0 πŸ“Œ 1

Konstanz School of Collective Behavior 2026 is one of a kind school where students delve into state of the art research on collective behavior.
Apply here: www.exc.uni-konstanz.de/kscb/applica...
Deadline: March 15th, 2026
@cbehav.bsky.social @mpi-animalbehav.bsky.social @uni-konstanz.de

05.02.2026 06:17 πŸ‘ 12 πŸ” 10 πŸ’¬ 0 πŸ“Œ 2

Baseline activity of V1 interneurons connects pupil-linked arousal to engaged behavioral state https://www.biorxiv.org/content/10.64898/2026.02.05.704022v1

08.02.2026 00:15 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Orofacial behaviors, not eye movements, govern neural activity in mouse visual cortex https://www.biorxiv.org/content/10.64898/2026.02.04.703800v1

05.02.2026 10:16 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Presynaptic control of top-down signaling in neocortical layer 1 https://www.biorxiv.org/content/10.64898/2026.01.31.703032v1

02.02.2026 05:15 πŸ‘ 8 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
NOT-OD-26-020: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NOT-OD-26-020. OD

Notice of Extension to Early-Stage Investigator (ESI) Eligibility Period by NIH: Investigators whose ESI end date was in Sept, Oct, or Nov 2025 will have ESI status extended through March 31, 2026

But what about if the end date was Dec 25 or Jan 26?
grants.nih.gov/grants/guide...

30.01.2026 20:06 πŸ‘ 1 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
A functional influence based circuit motif that constrains the set of plausible algorithms of cortical function There are several plausible algorithms for cortical function that are specific enough to make testable predictions of the interactions between functionally identified cell types. Many of these algorithms are based on some variant of predictive processing. Here we set out to experimentally distinguish between two such predictive processing variants. A central point of variability between them lies in the proposed vertical communication between layer 2/3 and layer 5, which stems from the diverging assumptions about the computational role of layer 5. One assumes a hierarchically organized architecture and proposes that, within a given node of the network, layer 5 conveys unexplained bottom-up input to prediction error neurons of layer 2/3. The other proposes a non-hierarchical architecture in which internal representation neurons of layer 5 provide predictions for the local prediction error neurons of layer 2/3. We show that the functional influence of layer 2/3 cell types on layer 5 is incompatible with the hierarchical variant, while the functional influence of layer 5 cell types on prediction error neurons of layer 2/3 is incompatible with the non-hierarchical variant. Given these data, we can constrain the space of plausible algorithms of cortical function. We propose a model for cortical function based on a combination of a joint embedding predictive architecture (JEPA) and predictive processing that makes experimentally testable predictions. ### Competing Interest Statement The authors have declared no competing interest. Swiss National Science Foundation, https://ror.org/00yjd3n13 Novartis Foundation, https://ror.org/04f9t1x17 European Research Council, https://ror.org/0472cxd90, 865617

Our work with @georgkeller.bsky.social on testing predictive processing (PP) models in cortex is out on biorvix now! www.biorxiv.org/content/10.6... A short thread on our findings and thoughts on where we should move on from PP below.

30.01.2026 14:37 πŸ‘ 47 πŸ” 16 πŸ’¬ 2 πŸ“Œ 1
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Cholinergic modulation of dopamine release drives effortful #behavior Nature, Published online: 28 January 2026; doi:10.1038/s41586-025-10046-6In the nucleus accumbens, acetylcholine boosts dopamine release to promote effortful behaviour.

Cholinergic modulation of dopamine release drives effortful #behavior @Nature.com

29.01.2026 22:32 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
Frequently Asked Questions (FAQs) | Grants & Funding

"NIH will provide a warning when the Common Forms are not used but will not withdraw applications that don’t comply with the use of the Common Forms. We expect the leniency to be in place through May 2026"

grants.nih.gov/faqs#/common...

29.01.2026 22:02 πŸ‘ 6 πŸ” 10 πŸ’¬ 1 πŸ“Œ 2
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience

If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd
parisneuro.ovh

28.01.2026 21:54 πŸ‘ 15 πŸ” 15 πŸ’¬ 3 πŸ“Œ 0
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Spontaneous behavior is a succession of self-directed tasks Weinreb et al. reveal a hierarchy of timescales in mouse behavior, including low-level syllables and high-level behavioral states. States and syllables are encoded in different brain areas. Prefrontal encoding of behavioral states identifies principles common to both structured tasks and spontaneous behavior.
28.01.2026 19:36 πŸ‘ 19 πŸ” 6 πŸ’¬ 0 πŸ“Œ 2
Attention-like regulation of theta sweeps in the brain's spatial navigation circuit Spatial attention supports navigation by prioritizing information from selected locations. A candidate neural mechanism is provided by theta-paced sweeps in grid- and place-cell population activity, which sample nearby space in a left-right-alternating pattern coordinated by parasubicular direction signals. During exploration, this alternation promotes uniform spatial coverage, but whether sweeps can be flexibly tuned to locations of particular interest remains unclear. Using large-scale Neuropixels recordings in freely-behaving rats, we show that sweeps and direction signals are rapidly and dynamically modulated: they track moving targets during pursuit, precede orienting responses during immobility, and reverse during backward locomotion β€” without prior spatial learning. Similar modulation occurs during REM sleep. Canonical head-direction signals remain head-aligned. These findings identify sweeps as a flexible, attention-like mechanism for selectively sampling allocentric cognitive maps. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, Synergy Grant 951319 (EIM) The Research Council of Norway, Centre of Neural Computation 223262 (EIM, MBM), Centre for Algorithms in the Cortex 332640 (EIM, MBM), National Infrastructure grant (NORBRAIN, 295721 and 350201) The Kavli Foundation, https://ror.org/00kztt736 Ministry of Science and Education, Norway (EIM, MBM) Faculty of Medicine and Health Sciences; NTNU, Norway (AZV)

The hippocampal map has its own attentional control signal!
Our new study reveals that theta #sweeps can be instantly biased towards behaviourally relevant locations. See πŸ“Ή in post 4/6 and preprint here πŸ‘‰
www.biorxiv.org/content/10.6...
🧡(1/6)

28.01.2026 10:03 πŸ‘ 183 πŸ” 62 πŸ’¬ 4 πŸ“Œ 10
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He is just like a big dog

25.01.2026 20:34 πŸ‘ 133 πŸ” 17 πŸ’¬ 6 πŸ“Œ 0
How the human brain is like a murmuration of starlings | Aeon Essays The brain is much less like a machine than it is like the murmurations of a flock of starlings or an orchestral symphony

"The brain is much less like a machine than it is like the murmurations of a flock of starlings. Behaviors arise from interactions, not central control.”

Essay by Luis @pessoabrain.bsky.social #Neuroscience #ComplexityScience #CognitiveScience

18.01.2026 23:45 πŸ‘ 27 πŸ” 4 πŸ’¬ 2 πŸ“Œ 0
Purple white and yellow flowers

Purple white and yellow flowers

Riverside super bloom with desert wishbone, fiddlenecks and popcorn flowers #NativePlants

19.01.2026 01:14 πŸ‘ 60 πŸ” 5 πŸ’¬ 1 πŸ“Œ 0
Applications for 2026 entry to the Gatsby Bridging Programme (7-week maths summer school) will open on 19 Jan and close on 16 Feb. Designed for students who wish to pursue a postgrad research degree in theoretical neuroscience or foundational machine learning but whose degree programme lacks a strong maths focus. Applications from students in underrepresented groups in STEM strongly encouraged. A small number of bursaries available.
Register for the information webinar on 23 Jan.

Applications for 2026 entry to the Gatsby Bridging Programme (7-week maths summer school) will open on 19 Jan and close on 16 Feb. Designed for students who wish to pursue a postgrad research degree in theoretical neuroscience or foundational machine learning but whose degree programme lacks a strong maths focus. Applications from students in underrepresented groups in STEM strongly encouraged. A small number of bursaries available. Register for the information webinar on 23 Jan.

πŸ“’ Applications open on 19 Jan for the 7-week #Mathematics #SummerSchool in London. You will develop the maths skills and intuition necessary to enter the #TheoreticalNeuroscience / #MachineLearning field.

Find out more & register for the information webinar πŸ‘‰ www.ucl.ac.uk/life-science...

15.01.2026 14:37 πŸ‘ 25 πŸ” 27 πŸ’¬ 1 πŸ“Œ 1
It is also very curiously displayed in the side fin, the bones of which almost exactly answer to the bones of the human hand, minus only the thumb. This fin has four regular bone-fingers, the index, middle, ring, and little finger.

It is also very curiously displayed in the side fin, the bones of which almost exactly answer to the bones of the human hand, minus only the thumb. This fin has four regular bone-fingers, the index, middle, ring, and little finger.

That said, this part at the end of the chapter is pretty impressive. Moby-Dick was published in 1851; the Origin of Species in 1859. Melville probably didn't have much knowledge of the "correspondences" that anatomists were trying so hard to understand, but he's absolutely correct here. πŸ‹

17.01.2026 01:49 πŸ‘ 14 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Computational psychiatry needs systems neuroscience Dissecting different parallel processing streams may help us understand the mechanisms underlying psychiatric symptoms, such as delusions, and unite human and animal research.

Dissecting different parallel processing streams may help us understand the mechanisms underlying psychiatric symptoms, such as delusions, and unite human and animal research, writes Michael Halassa.

#neuroskyence

www.thetransmitter.org/psychiatry/c...

13.01.2026 14:36 πŸ‘ 9 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
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Behavioral Signatures of Post-Decisional Attention in Preferential Choice Attention plays a key role in decision-making by directing limited cognitive resources to relevant information. It has been proposed that attention also biases the decision process, due to a multiplic...

New preprint: visual attention may follow decisions more than it shapes them.
We identify behavioral signatures inconsistent with models in which attention affects value, instead pointing to a substantial post-decisional component.
www.biorxiv.org/content/10.6...

12.01.2026 23:41 πŸ‘ 12 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0
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Probationary (TenureTrack) Faculty Position-Systems Neuroscience in Higher Order Cognitive Circuits - London, Ontario (CA) job with Western University - Schulich School of Medicine and Dentistry | 128... Full-time probationary faculty position at the rank of Assistant Professor in the area of neural circuits in non-human primates.

Come join us. Western University invites applications from outstanding early career investigators for a full-time probationary faculty position at the rank of Assistant Professor in the area of neural circuits in NHPs. www.nature.com/naturecareer...

10.01.2026 20:25 πŸ‘ 24 πŸ” 27 πŸ’¬ 0 πŸ“Œ 0

With some trepidation, I'm putting this out into the world:
gershmanlab.com/textbook.html
It's a textbook called Computational Foundations of Cognitive Neuroscience, which I wrote for my class.

My hope is that this will be a living document, continuously improved as I get feedback.

09.01.2026 01:27 πŸ‘ 585 πŸ” 237 πŸ’¬ 16 πŸ“Œ 10
Chicken House Books website Website of Chicken House Books, publishers of James Dashner.

YA sci-fi and fantasy writers, a children's fiction competition with a 10,000 GBP prize & publishing contract - deadline June 2026.
For a "completed full-length novel for readers aged 7-18" written in English.
#writingcommunity #SFF #YA #YoungAdult
www.chickenhousebooks.com/submissions/

08.01.2026 05:11 πŸ‘ 33 πŸ” 30 πŸ’¬ 0 πŸ“Œ 0