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Una Wen-lii Nattermann

@unattermann

she/her | co-founder & scientist at Pioneer Labs | protein designer & microbial engineer | interested in biotech for sustainability on Earth & beyond πŸ§¬πŸ¦ πŸ’«

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Latest posts by Una Wen-lii Nattermann @unattermann

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πŸš€ Announcing the 2025 Protein Engineering Tournament.

This year’s challenge: design PETase enzymes, which degrade the type of plastic in bottles. Can AI-guided protein design help solve the climate crisis? Let’s find out! ⬇️

#AIforBiology #ClimateTech #ProteinEngineering #OpenScience

08.07.2025 16:26 πŸ‘ 23 πŸ” 20 πŸ’¬ 1 πŸ“Œ 4
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Heads up: terraforming Mars isn’t just sci-fi, it’s a real possibility that’s possible with today’s technology.

Mars could be green in MY lifetime. πŸš€ 🌼

What’s stopping us? We need a lot more real research into how to do it right. Don’t nuke Mars!

πŸ‘‡

13.05.2025 15:54 πŸ‘ 32 πŸ” 7 πŸ’¬ 4 πŸ“Œ 3

With bioinformatics, we’re now measuring the fitnesses of millions of DNA fragments! This gets us data on whole genomes and is the first step toward big data for modeling genotype -> phenotype with AI/ML for microbial evolution. Link in comments.

🧬 + πŸ”’ = πŸ“ˆ -> πŸ€–?

09.05.2025 00:34 πŸ‘ 4 πŸ” 1 πŸ’¬ 1 πŸ“Œ 1
Genotype to Phenotype: Design of an Extensible Experimental Platform for Characterizing Microbes

πŸš€ New proposal from Align! The experimental platform aims to standardize #microbial #phenotyping & support predictive modeling. 🦠 Capturing data across 1k strains & 1k conditions; using BacterAI; generating high-quality datasets for ML @jensen_lab

13.03.2025 20:58 πŸ‘ 3 πŸ” 4 πŸ’¬ 0 πŸ“Œ 1

We want to engineer microbes that can get all essential nutrients from Mars. To do so, we need to know what is biologically accessible so we did a deep dive into how Mars regolith has been simulated & suggest a liquid media recipe for testing & engineering strains. Read more πŸ‘‡πŸΌ

10.12.2024 19:46 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Ever wonder how we’ll unlock Mars as a living world? 🌏 In our substack post we break down the 'red planet recipe'β€”the chemistry of mars soil β€” for growing life on another world. Dive into the science to find out more!

10.12.2024 17:31 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

The first astronauts on Mars will use bacteria to make food, therapeutics & building materials.

What do you feed the 🦠? Here's the recipe:
- 40g of Mars dirt
- 1 liter of water
- Mix and strain

In our substack post, Pioneer Labs defines how to mimic this recipe on Earth. πŸš€πŸŒΌ

10.12.2024 17:28 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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πŸ† A Biologist’s Guide to Mars Dirt Just add water

Check out πŸ†A Biologist’s Guide to Mars Dirt, where we present a receipt for soluble Mars Regolith Media (sMRM) that best simulates what you’d get if you added water to Mars dirt.

Will anything grow in this media? Stay tuned!

πŸ’§+ πŸͺ¨ β†’ 🌱 ?

open.substack.com/pub/pioneerl...

10.12.2024 17:27 πŸ‘ 13 πŸ” 8 πŸ’¬ 0 πŸ“Œ 3

Want to follow along as we engineer microbes for circular biomanufacturing in space? We're launching open science updates through our substack! ⬇️

20.11.2024 00:32 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Would love to be added, thank you for putting this together!

19.11.2024 23:52 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0