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Jun Ishigohoka

@junishigohoka

Evolutionary biologist. Phenotypic noise < bird migration genomics Tübingen < Plön < Kiel < Sapporo < Tokyo https://junishigohoka.github.io/

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09.02.2024
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Latest posts by Jun Ishigohoka @junishigohoka

Professorship in population genetics in the field of evolutionary anthropology and medicine (W2) Faculties & Facilities

Leipzig U and the MPI for Evolutionary Anthropology (MPI-EVA) have an open faculty position (W2) in evolutionary population genetics! This position is tenured and comes with generous core funding. We are eager to welcome a new colleague! Deadline March 11.
www.uni-leipzig.de/en/newsdetai...

05.03.2026 16:38 👍 58 🔁 97 💬 0 📌 0
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Excited to see our FML Research Group Leader
@luisapallares.bsky.social
in the latest Max Planck Research! 🎉
The article follows her journey from Colombia to Germany and her work on how genes and environment shape complex traits using fruit flies.

Read the full story: www.mpg.de/26180374/W00...

05.03.2026 14:10 👍 46 🔁 11 💬 0 📌 2

@jomcinerney.bsky.social proposes that genomes do not encode fixed functions but rather “probability distributions” over functional and phenotypic outcomes, and introduces “genomic perplexity” as a measure of gene-context incompatibility.

🔗 doi.org/10.1093/molbev/msag041

#evobio #molbio

04.03.2026 16:03 👍 16 🔁 5 💬 2 📌 0
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Strain variation identifies a neural substrate for behavioral evolution in Drosophila Sexual selection acts on heritable differences within species, driving the parallel diversification of signal production in one sex and behavioral res…

www.sciencedirect.com/science/arti...

27.02.2026 17:53 👍 0 🔁 3 💬 0 📌 0

New teaching neurosis drops.
Student: It's funny. When I listen to the lecture recording the microphone picks up you heart beating, and so I can hear when you get nervous.
<sees look on my face>
Oh don't worry, it's not very noticeable.
2nd Student: Oh yeah, I've totally noticed that too!

27.02.2026 06:11 👍 48 🔁 5 💬 3 📌 0
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I used Claude Opus 4.5/4.6 (and a bit of Codex GPT-5.3) to port edgeR to Python. See edgePython github.com/pachterlab/e...
This allowed me to develop a single-cell DE method that extends NEBULA with edgeR Empirical Bayes. All in one week. Details in doi.org/10.64898/202...

19.02.2026 16:46 👍 68 🔁 25 💬 3 📌 3
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Screening, sorting, and the feedback cycles that imperil peer review The process of peer review is vital to contemporary science, but is also under enormous strain. This study uses mathematical models to dissect the threats to the long-term viability of peer review, su...

1. Kevin Gross and I have a new paper out today PLOS Biology.

We used economic models based around screening games and the market for unpaid labor to highlight a meltdown cycle threatening peer review.

24.02.2026 20:54 👍 324 🔁 132 💬 8 📌 17
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Have you ever wondered 🤔... Does phenotypic variance respond to environmental perturbation? Does it have a genetic basis? Are mean and variance regulating loci exposed to different selection pressures? These and more questions are explored in our new preprint 🔥

www.biorxiv.org/content/10.6...

23.02.2026 15:37 👍 85 🔁 48 💬 2 📌 4
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Our BehaveAI paper has just come out!

Easy & effective tracking & behavioural classification, even with tiny (2px), fast moving, camouflaged objects.

Paper: doi.org/10.1371/jour...
Download: github.com/troscianko/B...

@uniexecec.bsky.social @kevinjgaston.bsky.social @jimamclgalloway.bsky.social

21.02.2026 09:02 👍 87 🔁 36 💬 4 📌 1
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Proud to present: Suitcase Science, a new outreach format containing 6 assignments to take on a journey to schools in the region, to teach kids about terns, how to study them, their fascinating behaviour and some of the things that threaten them. Wanna book us? Drop me a line. :-)

02.02.2026 13:44 👍 26 🔁 11 💬 1 📌 1
"Nothing could be less inviting than the first appearance. A broken field of black basaltic lava, thrown into the most rugged waves, and crossed by great fissures, is everywhere covered by stunted, sun-burnt brushwood, which shows little signs of life. The dry and parched surface, being heated by the noon-day sun, gave to the air a close and sultry feeling, like that from a stove: we fancied even that the bushes smelt unpleasantly. Although I diligently tried to collect as many plants as possible, I succeeded in getting very few; and such wretched-looking little weeds would have better become an arctic than an equatorial Flora."

"Nothing could be less inviting than the first appearance. A broken field of black basaltic lava, thrown into the most rugged waves, and crossed by great fissures, is everywhere covered by stunted, sun-burnt brushwood, which shows little signs of life. The dry and parched surface, being heated by the noon-day sun, gave to the air a close and sultry feeling, like that from a stove: we fancied even that the bushes smelt unpleasantly. Although I diligently tried to collect as many plants as possible, I succeeded in getting very few; and such wretched-looking little weeds would have better become an arctic than an equatorial Flora."

In celebration of #DarwinDay, here are his decidedly mixed first impressions after landing on the Galápagos (17 Sept 1835; from 'the Voyage' Chap X):

"Nothing could be less inviting..."

12.02.2026 14:31 👍 47 🔁 13 💬 5 📌 0
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A POMT2 missense substitution contributes to hypoxia adaptation in hibernating mammals Abstract. Hibernation is an adaptive survival strategy used by animals to cope with extreme environmental conditions. Although this physiological process i

Zhang et al. compared the genomes of six hibernating mammals, identifying an ancient amino acid substitution in POMT2 exhibiting signals of both convergent and positive selection. Functional studies demonstrated a role in hypoxia adaptation.

🔗 doi.org/10.1093/molbev/msag001

#evobio #molbio

04.02.2026 09:13 👍 4 🔁 3 💬 0 📌 1

elifesciences.org/articles/105...

04.02.2026 16:17 👍 0 🔁 0 💬 0 📌 0
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Heritability of intrinsic human life span is about 50% when confounding factors are addressed How heritable is human life span? If genetic heritability is high, longevity genes can reveal aging mechanisms and inform medicine and public health. However, current estimates of heritability are low...

www.science.org/doi/10.1126/...

31.01.2026 20:50 👍 0 🔁 0 💬 0 📌 0
Scientific strides #comedy #standup
Scientific strides #comedy #standup YouTube video by Jordan Jensen

Postdoc Yannick Günzel, who studies how clonal raider ants interact with their larvae, went to a comedy show in NYC. Now he’s famous… 🤪

youtube.com/shorts/ZETUy...

24.01.2026 18:45 👍 43 🔁 8 💬 5 📌 1
Throat coloration in common wall lizards (Podarcis muralis). From top to bottom: White morph with the characteristic green and black coloration of the nigriventris syndrome; White morph with the ancestral brown phenotype; yellow and orange morphs from populations where individuals show varying expression of the nigriventris characters.

Throat coloration in common wall lizards (Podarcis muralis). From top to bottom: White morph with the characteristic green and black coloration of the nigriventris syndrome; White morph with the ancestral brown phenotype; yellow and orange morphs from populations where individuals show varying expression of the nigriventris characters.

Two new Science studies on lizard coloration reveal how a delicate interplay of genetics, environment, and social dynamics can either preserve or erase polymorphic diversity in species.

📄: https://scim.ag/4srYKHi
📄: https://scim.ag/4qCcsWn

09.01.2026 20:56 👍 48 🔁 11 💬 0 📌 0
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‘I rarely get outside’: scientists ditch fieldwork in the age of AI Nature - In the race to embrace new technologies, some ecologists fear their field is losing touch with nature.

Some researchers are now studying ecology without touching a single plant

go.nature.com/4aRGile

10.01.2026 09:47 👍 29 🔁 12 💬 2 📌 4

It is out, it is out! Our study on neural crest cells and micro to macroevolution in lizard skull 🦎

08.01.2026 09:44 👍 6 🔁 2 💬 0 📌 0

Final version of paper with @smishra677.bsky.social now published in a wonderful issue of GENETICS!

academic.oup.com/genetics/art...

08.01.2026 13:57 👍 26 🔁 16 💬 0 📌 0
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Not Just Ne Ne-More: New Applications for SMC from Ecology to Phylogenies Abstract. Genomes contain the mutational footprint of an organism’s evolutionary history, shaped by diverse forces including ecological factors, selective

In a new GBE Review, @david-peede.bsky.social et al. overview the SMC model and extensions, discuss examples of discoveries made with the help of SMC-based inference, and comment on the assumptions, benefits, and drawbacks of various methods.

🔗 doi.org/10.1093/gbe/...

#genome #evolution #compbio

08.01.2026 08:05 👍 36 🔁 20 💬 1 📌 2
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The genetics, evolution, and maintenance of a biological rock-paper-scissors game Side-blotched lizards (Uta stansburiana) play a biological rock-paper-scissors game in which three differently colored male morphs utilize alternative mating strategies. We identified the genetic basi...

www.science.org/doi/10.1126/...

02.01.2026 22:01 👍 1 🔁 0 💬 0 📌 0
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Defensive fungal symbiosis on insect hindlegs Dinidorid stinkbugs were reported to possess a conspicuous tympanal organ on female hindlegs. In this study, we show that this organ is specialized to retain microbial symbionts rather than to perceiv...

What looked like a hearing organ on a tiny stinkbug’s leg turned out to be something far stranger: a fungal nursery that mother bugs use to coat their newly laid eggs in protective symbiotic hyphae, shielding their offspring from parasitic wasps, a Science study finds. https://scim.ag/3MXQ4bt

31.12.2025 20:15 👍 97 🔁 27 💬 1 📌 3
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🧬 Just out in Bioinformatics Advances: “tskit arg visualizer: Interactive plotting of ancestral recombination graphs.” 

Read the full paper here: https://doi.org/10.1093/bioadv/vbaf302

Authors include: @kitchensjn.bsky.social, @yanwong.bsky.social

18.12.2025 10:02 👍 18 🔁 13 💬 1 📌 0
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Can we predict gene expression evolution? In flour beetles, transcriptome-wide selection predicts expression change, with indirect selection acting strongest on pleiotropic, network-central genes—linking co-expression architecture to adaptation.
academic.oup.com/evlett/artic... Photo: Udo Schmidt

18.12.2025 13:01 👍 20 🔁 8 💬 0 📌 1
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Multivariate trait evolution: models for the evolution of the quantitative genetic G-matrix on phylogenies Abstract. Genetic covariance matrices (G-matrices) are a key focus for research and predictions from quantitative genetic evolutionary models of multiple t

academic.oup.com/evlett/artic...

19.12.2025 12:56 👍 0 🔁 0 💬 0 📌 0

demografr: A toolkit for simulation-based inference in population genetics https://www.biorxiv.org/content/10.64898/2025.12.18.694482v1

19.12.2025 07:31 👍 11 🔁 9 💬 0 📌 1
Quantitative genetics of reaction norms: an onion partitionning – Pierre de Villemereuil

Took me a year (😱), but I finally published a blog post about our article on the #quantgen variance partition of phenitypic plasticity with @lmchev.bsky.social, published in @peercomjournal.bsky.social.

🇬🇧 devillemereuil.legtux.org/quantitative...
🇫🇷 devillemereuil.legtux.org/fr/genetique...

10.12.2025 10:48 👍 20 🔁 10 💬 1 📌 2
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Summer school:<br> Evolutionary Biology in Guarda Information about the annual summer school Evolutionary Biology in Guarda

The 2026 Guarda Summer Course in Evolutionary Biology is now accepting applications. Amazing place, amazing course, amazing opportunity for early grad students.

tb.ethz.ch/education/gu...

10.12.2025 14:24 👍 65 🔁 72 💬 1 📌 4
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Have you ever wondered what you would find if you could keep your eyes on a bee for more than a few meters? Us, too!

preprint (with videos!) + thread 🧵

Precise, individualized foraging flights in honey #bees 🐝 revealed by multicopter drone-based tracking

www.biorxiv.org/content/10.6...

1/9

06.12.2025 13:57 👍 371 🔁 151 💬 9 📌 16
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An Expectation and Maximization Algorithm for Multivariate Genome-wide Association Studies (EMmvGWAS) Genome-wide association studies (GWAS) often analyze one trait at a time, but multivariate GWAS can increase the power by leveraging trait correlations. However, existing methods struggle with high co...

www.biorxiv.org/content/10.6...

05.12.2025 21:58 👍 0 🔁 0 💬 0 📌 0