The molecular basis of force selectivity by PIEZO2 - Nature
PIEZO2 is intrinsically more rigid than PIEZO1, and disparate mechanical stimuli paradoxically evoke opposite conformational and gating responses in each channel.
Very excited to share our new manuscript β published today!
Why are PIEZO1 and PIEZO2 are tuned to transduce different types of mechanical force? I was lucky to work with some extraordinary colleagues to begin to figure out why.
www.nature.com/articles/s41...
An overview of the results below β¬οΈ β¬οΈ
05.03.2026 00:51
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A Cinderella story: raising CLIP-tag from the ashes to shine in fluorescence labeling.
www.biorxiv.org/content/10.6...
08.03.2026 09:28
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Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179
The structure of the orphan GPCR GPR179 bound to the extracellular matrix component pikachurin is solved.
What do you get when #NationalProteinDay and #NationalPokΓ©monDay meet? Pikachurin. β‘
A 2023 #ScienceSignaling study solved the structure of this extracellular protein that plays an essential role in vision.β
β
Learn more: https://scim.ag/4s82e0N
27.02.2026 14:31
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Redirecting
Full DOI: doi.org/10.1016/j.ch...
19.02.2026 11:28
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πRobust photoactivatable fluorescent markers with red and #far-red emission for live-cell imaging are difficult to find? Not anymore! Researchers at our Optical Nanoscopy Department have developed new far-red markers. Successfully used in STED, PALM and MINFLUX nanoscopy!π¬
doi.org/10.1016/j.ch...
16.02.2026 14:24
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π°π«Yogurt cinnamon cake with berries β sounds delicious, right? πThis is the winning cake in this year's great #MPImR bake off, baked by BetΓΌl Karakoc! π₯Congratulations, BetΓΌl, and many thanks to all our bakers for their yummy cakes, muffins, and more!β€οΈ
#bakeoff #bakesale #lifeisbetterwithcake
09.02.2026 16:06
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Happy to share the final chapter in the story of PaX Dyes, and my time at @stefanhelllabs.bsky.social at @mpi-mr.bsky.social! Now in @cp-chem.bsky.social, we access the red and far-red regions on the spectrum with our caging-group-free strategy for multicolor #SMLM, #STED, and #MINFLUX #microscopy!
02.02.2026 16:43
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Ho, ho, HO! βοΈ In celebration of #Nikolaus Day, our #MaxPlanck bust has received a festive holiday makeover.π
We hope your morning brought a pleasant surprise - whether in your stockings or winter boots. β¨Let's stay festive!π
#MPIMR #HolidaySeason
06.12.2025 11:15
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β¨Our new #ScienceSnapshot highlights PhD researcher Christopher Heidebrecht (Optical Nanoscopy) as he prepares samples for microscopy.π¬Stay tuned for more behind-the-scenes lab moments! πΈπ€© #MaxPlanck #MPIMR #Research #BehindTheScenes
05.12.2025 11:17
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EMBL TechDev Internship Programme β Scientific Visitor Programme
π Weβre hiring! EMBL TechDev Internship (TDI25-14)
Weβre looking for an organic chemist to help develop novel fluorogenic HaloTag ligands for deep-tissue imaging. Youβll contribute to molecular design and run in silico, in vitro, and microscopy-based assays to quantify fluorophore performance.
24.11.2025 14:34
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Itβs #TagDerSuppe!π² Our Single Molecule Sensing research group at the Institute keeps a weekly soup ritual.π As the weather turns colder, itβs the perfect opportunity to slow down, connect, and enjoy lunchtime together.β¨οΈ #MaxPlanck #MPIMR #DayOfTheSoup
19.11.2025 16:05
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Excited to share the second chapter of my PhD work - Photoclickable HaloTag Ligands for Spatiotemporal Multiplexed Protein Labeling on Living Cells! π₯³ A big thank you to @clairedeo.bsky.social and all co-authors who contributed to this work.
β‘οΈ www.biorxiv.org/content/10.1...
13.11.2025 17:53
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#Science met #curiosity!β¨
At the βHome game scienceβ talk yesterday in Bad SchΓΆnborn, our PhDs Ann-Kathrin Gelmroth & Philip Matthias shared how curiosity drives their #research: from #antibioticresistance to the beauty of #microscopy. Conversations continued long after the talkπ¬π§ͺ
#maxplanck #mpimr
13.11.2025 09:38
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Poster: Invitation to a lecture on Wednesday, November 12, at 7 p.m. in Bad SchΓΆnborn at CafΓ© Glashaus
Invitation to a #MaxPlanck Special edition of βHeimspiel Wissenschaftβ (home game science) π‘β¨! Scientists from more rural regions return to their hometowns and make #science accessible outside of large cities and university towns. Talk in German, this Wednesday with two of our PhDs! π§ͺπ¬
#mpimr
10.11.2025 11:32
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Amir Abdollahi, Dirk JΓ€ger und Peer Fischer
Zwei ERC Synergy Grants fΓΌr Wissenschaftler der UniversitΓ€t Heidelberg: EuropΓ€ischer Forschungsrat vergibt hochdotierte FΓΆrderungen fΓΌr komplexe Vorhaben in der Forschung www.uni-heidelberg.de/de/newsroom/...
#universitΓ€t #heidelberg #uniheidelberg #erc #forschungsrat #eu @erc.europa.eu
06.11.2025 11:28
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ERC Synergy Grant for MPI Director Kai Johnsson
ππBig news! Our Director @kjohnsson.bsky.social has received an @erc.europa.eu Synergy Grant, together with teams from EPFL @sulianamanley.bsky.social and @unibe.ch! πTheyβll explore how mitochondria communicate with other cell partsπ¬ #ERCSyG #maxplanck #mpimr #science
www.mr.mpg.de/14662972/erc...
06.11.2025 11:41
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"β¦ Goodallβs β¦ is a story of genuine scientific curiosity, determination, and respect for
nature and humanity β¦" H. Holden Thorp, Editor-in-chief, Science journals
Jane Goodall has died at the age of 91.
In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8
01.10.2025 19:13
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Looking forward to welcoming you in GΓΆttingenβs Max Planck community, @steffenmau.bsky.social! Congratulations to our colleagues at @mpimmg.bsky.social for this excellent appointment π!
02.10.2025 09:16
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Today's #MPIMRSpotlight features our PhD student Yuqi @yuqizhang.bsky.social β¨π She gives insights into her research in the Chemical Biology department ππ‘ #MaxPlanck #MPIMR #STEM #BehindTheScenes #womeninscience
18.09.2025 09:25
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Curious about MINFLUX but unsure how to handle sample prep? Already using MINFLUX and want better results?
Join our webinar on MINFLUX sample preparation:
link.abberior.rocks/sampleprep
π
Wed, Oct 1, 15:30 CEST
β
Easy-to-follow tips
β
Common mistakes to avoid
β
Live Q&A
#MINFLUX #SamplePrep
18.09.2025 13:23
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π Back from our #scientificretreat 2025 in Neckarsulm, full of scientific exchange and #teamspirit! π€©πOne highlight was the tour of the Bildungscampus in Heilbronn, where two new departments of our institute will be established, and the Innovation Park for #AI #IPAI π
#maxplanck #mpimr #letsmingle
18.09.2025 13:54
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Max Planck Institute is looking for a PhD
π£PhD position available! π¬The department of Stefan Hell is looking for a new group member working at the intersection of #optics, #molecularbiology and #biophysics. More info on our website, see link below!
#maxplanck #mpimr #science #phd #hiring
bewerbermanagement.net/jobposting/5...
09.09.2025 10:09
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π Take a glimpse at some behind-the-scenes moments from our recent Institute photoshoot! A huge thank you to photographer Alexander GrΓΌber and the creative team for making it such a fun and memorable experience. πΈβ¨ #MPIMR #Teamwork #Photoshoot #BehindTheScenes
24.07.2025 12:12
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π¬ Welcome back to #ScienceFunFactFriday! π
Ever wondered about the quirkiest science facts? We're here to share them! Dive into our team's top picks and share your own fun fact with us. Let's make science (even more) fun together! ππ§ #ScienceFun #FunFact #ScienceTrivia #MaxPlanck #MPIMR
11.07.2025 11:34
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ππ We're absolutely loving the Institute's summer party! The unexpected sunshine truly made our day. π¦βοΈ Delicious ice cream in hand and great company all around - what more could we ask for? π #MPIMR #BehindTheScenes #SummerFun
08.07.2025 13:00
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Max Planck Manatees team at the Dragon Boat Cup in Heidelberg today
π₯³ Hurray, Max Planck Manatees! Our team took part in the famous Dragon Boat Cup π² π£ in Heidelberg again today and came 14th out of 30 in the fun mix category. Congratulations, you did great!πͺ #dragonboatcup #mpimr #maxplanck #teamspirit #maxplanckmanatees
05.07.2025 17:53
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Well done, Team! Yesterday, 40 colleagues represented the MPI-NAT at GΓΆttingenβs annual Altstadtlauf. We are so proud of you for taking on this challenge and braving the summer heat πͺπ
03.07.2025 11:52
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π₯ Our fire protection officer Mario is training the team on handling unexpected fires in our facilities.These exercises cerainly match today's sizzling heat! ππ #FireSafety #StayCool #WorkplaceSafety #BehindTheScenes #MPIMR
01.07.2025 10:03
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#OnThisDay in 1993, CERN released the World Wide Web software to the public.
Proposed by Sir Tim Berners-Lee, the web was originally created to allow scientists and institutes working on CERN data to share information accurately and quickly from across the globe.
#WorldWideWeb
30.04.2025 08:47
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