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parm

@prmshra

CEO of Precigenetics Cancer drug discovery at the speed of light.

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08.09.2024
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Latest posts by parm @prmshra

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NCT04957719

12.10.2025 20:37 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

AMI is Acute myocardial infarction

It contributes to about 9M global deaths/yr from ischemic heart disease, with each 30-minute delay in STEMI treatment increasing 1-year mortality risk by 7.5%

12.10.2025 20:34 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

phase 2 data: 80% platelet inhibition within 15 minutes via subcutaneous injection, far quicker than oral antiplatelets.

12.10.2025 20:34 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

The phase 3 SOS-AMI trial, started in 2021, does test selatogrel in patients with prior AMI

12.10.2025 20:34 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

It’s investigational, not approved yet, but large outcome trials are underway. Early studies show rapid platelet inhibition, and the global SOS-AMI study is testing real-world outcomes.

12.10.2025 20:33 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Selatogrel auto-injector (SOS-AMI trial) is a fast-acting, subcutaneous P2Y₁₂ inhibitor designed to be self-injected at the first signs of a suspected heart attack (like chest pain), then followed by standard care.

12.10.2025 20:33 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Imagine if there was an EpiPen for heart attacks

How many lives it would save, especially if it could auto-inject in the case of one.

12.10.2025 20:32 πŸ‘ 5 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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My coolest tweet ever.

Didn’t know how far I would come so fast.

Thank you to my backers.

12.10.2025 13:37 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Just a girl and her robots.

12.10.2025 13:35 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Eli Lilly just entered a $1.3B deal with a biotech to leverage AI for drug discovery in cardiometabolic diseases and obesity

People are still arguing about whether AI is useful for drug discovery on X while the entire industry is doubling down over and over again

12.10.2025 13:33 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Digitizing biology like we digitized intelligence

www.precigenetics.com/blog/digitiz...

12.10.2025 13:21 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

blindspots of humanity
1. Thinking past one’s own lifespan
2. Epigenetics
3. Scaling laws
4. Compounding
5. Nonlinear complexity
6. Rationality is cognitive bias
7. Mind-body
8. Linguistic relativity
9. Subclinical, pre disease states
10. Light is a wave and a particle

12.10.2025 13:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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I am the CEO of Precigenetics.

We are building a platform that virtual stains cells without killing them. And watches these cells as they interact with drugs in real time.

This is our platform LUMA v0.1.

We built it in 7 months with our own hardware and spectral sensors.

Only up from here.

12.10.2025 13:19 πŸ‘ 4 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Even people who think AI in biology is a grift (lol) cannot argue against these two.

If you think AI is a scam here, that is either a data issue or a skill issue.

12.10.2025 13:13 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

The 2 simplest ways AI helps biology
- parsing multimodal data in parallel to choose the best data for a human to look at reducing inefficiency
- embed large # of signals about cells and clusters of cells to create lower-dimensional representations that are more human interpretable in the 3D/4D.

12.10.2025 13:13 πŸ‘ 2 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

saying AI in biology is a scam is more about your lack of understanding of its strengths and limitations. It is quite like saying computers in biology are a scam.

12.10.2025 13:13 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

might not reflect in the stock market just yet. tens of insanely lucrative partnerships have been initiated in AI drug discovery every single year this decade

12.10.2025 13:01 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

In a few years from now, AI drug discovery platforms will become more lucrative that they look

just because AI drug discovery doesn’t have the same hype bubble as an OpenAI or a Thinking Machines Lab, does not mean that it’s not already priced in by pharma.

12.10.2025 13:01 πŸ‘ 5 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0

lol

10.01.2025 16:36 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

[ cue someone insulting you for using the word diversify ]

02.01.2025 19:00 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

In ONE WEEK it degenerated man

Diversify your portfolio! Diversify your portfolio!

02.01.2025 13:40 πŸ‘ 1 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

X dot com has become one massive midwit rage bait machine.

02.01.2025 13:38 πŸ‘ 8 πŸ” 1 πŸ’¬ 3 πŸ“Œ 0

β€œWhy are you on bluesky” let me tell you something. Hearing people with 90 IQ telling me I am a smelly Indian any time I say things gets old at some point

02.01.2025 13:16 πŸ‘ 5 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I am a 25 year old biotech founder and I have 18 year old men who just enrolled in IIT comp sci mansplaining biology to me

02.01.2025 12:37 πŸ‘ 8 πŸ” 0 πŸ’¬ 2 πŸ“Œ 0

Young men are increasingly single because they’re in a one sided relationship with Elon Musk

02.01.2025 10:14 πŸ‘ 7 πŸ” 2 πŸ’¬ 1 πŸ“Œ 0

Once you open that can of worms, that is the approval of someone else, you might as well lose your real self

02.01.2025 10:12 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Placating is the worse thing in the world. Never placate. It’s a never ending circle

02.01.2025 10:10 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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don’t hug me

02.01.2025 10:02 πŸ‘ 4 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

reminds me a bit of the internet before it became really massive. a place for people to cultivate their niche interests, where things had their own places instead of fighting it on huge general purpose platforms.

18.11.2024 09:03 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

i looked at this and thought they were photodiodes for a second

18.11.2024 06:25 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0