NCT04957719
NCT04957719
AMI is Acute myocardial infarction
It contributes to about 9M global deaths/yr from ischemic heart disease, with each 30-minute delay in STEMI treatment increasing 1-year mortality risk by 7.5%
phase 2 data: 80% platelet inhibition within 15 minutes via subcutaneous injection, far quicker than oral antiplatelets.
The phase 3 SOS-AMI trial, started in 2021, does test selatogrel in patients with prior AMI
Itβs investigational, not approved yet, but large outcome trials are underway. Early studies show rapid platelet inhibition, and the global SOS-AMI study is testing real-world outcomes.
Selatogrel auto-injector (SOS-AMI trial) is a fast-acting, subcutaneous P2Yββ inhibitor designed to be self-injected at the first signs of a suspected heart attack (like chest pain), then followed by standard care.
Imagine if there was an EpiPen for heart attacks
How many lives it would save, especially if it could auto-inject in the case of one.
My coolest tweet ever.
Didnβt know how far I would come so fast.
Thank you to my backers.
Just a girl and her robots.
Eli Lilly just entered a $1.3B deal with a biotech to leverage AI for drug discovery in cardiometabolic diseases and obesity
People are still arguing about whether AI is useful for drug discovery on X while the entire industry is doubling down over and over again
Digitizing biology like we digitized intelligence
www.precigenetics.com/blog/digitiz...
blindspots of humanity
1. Thinking past oneβs own lifespan
2. Epigenetics
3. Scaling laws
4. Compounding
5. Nonlinear complexity
6. Rationality is cognitive bias
7. Mind-body
8. Linguistic relativity
9. Subclinical, pre disease states
10. Light is a wave and a particle
I am the CEO of Precigenetics.
We are building a platform that virtual stains cells without killing them. And watches these cells as they interact with drugs in real time.
This is our platform LUMA v0.1.
We built it in 7 months with our own hardware and spectral sensors.
Only up from here.
Even people who think AI in biology is a grift (lol) cannot argue against these two.
If you think AI is a scam here, that is either a data issue or a skill issue.
The 2 simplest ways AI helps biology
- parsing multimodal data in parallel to choose the best data for a human to look at reducing inefficiency
- embed large # of signals about cells and clusters of cells to create lower-dimensional representations that are more human interpretable in the 3D/4D.
saying AI in biology is a scam is more about your lack of understanding of its strengths and limitations. It is quite like saying computers in biology are a scam.
might not reflect in the stock market just yet. tens of insanely lucrative partnerships have been initiated in AI drug discovery every single year this decade
In a few years from now, AI drug discovery platforms will become more lucrative that they look
just because AI drug discovery doesnβt have the same hype bubble as an OpenAI or a Thinking Machines Lab, does not mean that itβs not already priced in by pharma.
lol
[ cue someone insulting you for using the word diversify ]
In ONE WEEK it degenerated man
Diversify your portfolio! Diversify your portfolio!
X dot com has become one massive midwit rage bait machine.
βWhy are you on blueskyβ let me tell you something. Hearing people with 90 IQ telling me I am a smelly Indian any time I say things gets old at some point
I am a 25 year old biotech founder and I have 18 year old men who just enrolled in IIT comp sci mansplaining biology to me
Young men are increasingly single because theyβre in a one sided relationship with Elon Musk
Once you open that can of worms, that is the approval of someone else, you might as well lose your real self
Placating is the worse thing in the world. Never placate. Itβs a never ending circle
donβt hug me
reminds me a bit of the internet before it became really massive. a place for people to cultivate their niche interests, where things had their own places instead of fighting it on huge general purpose platforms.
i looked at this and thought they were photodiodes for a second