Aura Carreira's Avatar

Aura Carreira

@acarreiralab

Scientist interested in genome integrity maintenance mechanisms and cancer

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14.11.2024
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Latest posts by Aura Carreira @acarreiralab

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We just published a short conceptual review together with @angela-taddei.bsky.social on the spatial controls of homology search in both bacteria and eukaryotes. We discuss an emerging framework for homology search in cells with two main phases. Check it out: authors.elsevier.com/c/1mjyh,LqAZ...

09.03.2026 14:36 👍 17 🔁 10 💬 2 📌 0
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📣 16th edition of the French 3R meeting “Replication, Recombination, Repair” - Registrations are open!

📆 May 18 to 21, 2026
📍 Belambra Club Presqu’île du Ponant in La Grande-Motte, France

🔗 www.2026.3r-meeting.fr/page/home/

29.01.2026 10:03 👍 4 🔁 3 💬 0 📌 2
A color outdoor portrait of American bacterial geneticist Evelyn Witkin in her later years, standing in a sun-dappled garden or courtyard setting with green foliage and a brick building in the soft-focus background. She is an elderly woman with fair skin, short wavy white hair, gentle smile lines, and warm, thoughtful eyes gazing directly at the camera with a kind, serene expression. She wears a white button-up blouse with subtle textured patterns, small earrings, and a distinctive beaded necklace featuring dark and light beads. A small silver dragonfly brooch is pinned to the left side of her blouse, symbolizing her pioneering work on DNA damage repair (often likened to cellular "rescue" mechanisms). The natural daylight softly illuminates her face, highlighting her dignified and approachable presence as a trailblazing scientist and a Lasker Award and National Medal of Science recipient. The overall mood is one of quiet wisdom, resilience, and quiet celebration of a long, impactful career in #WomenInScience. #WomensHistoryMonth

A color outdoor portrait of American bacterial geneticist Evelyn Witkin in her later years, standing in a sun-dappled garden or courtyard setting with green foliage and a brick building in the soft-focus background. She is an elderly woman with fair skin, short wavy white hair, gentle smile lines, and warm, thoughtful eyes gazing directly at the camera with a kind, serene expression. She wears a white button-up blouse with subtle textured patterns, small earrings, and a distinctive beaded necklace featuring dark and light beads. A small silver dragonfly brooch is pinned to the left side of her blouse, symbolizing her pioneering work on DNA damage repair (often likened to cellular "rescue" mechanisms). The natural daylight softly illuminates her face, highlighting her dignified and approachable presence as a trailblazing scientist and a Lasker Award and National Medal of Science recipient. The overall mood is one of quiet wisdom, resilience, and quiet celebration of a long, impactful career in #WomenInScience. #WomensHistoryMonth

Geneticist Evelyn Witkin (b. #OTD 1921) pioneered work on DNA damage repair & mutagenesis.

Her discovery of the SOS response revealed how cells actively respond to genetic threats, laying foundations for insights into cancer, aging, radiation effects & chemotherapy resistance. #WomenInSTEM #WHM

09.03.2026 22:17 👍 563 🔁 120 💬 7 📌 7
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On se prépare au pied du Panthéon et partout en France pour faire vivre l'espoir contre le cancer ! Dès demain et tout au long du mois de mars, l'Institut Curie vous donne rendez-vous pour soutenir la recherche et l’innovation médicale avec #UneJonquilleContreleCancer.

09.03.2026 09:31 👍 2 🔁 4 💬 0 📌 0
Flyer for symposium: https://ctrlepiedit.sciencesconf.org/

Flyer for symposium: https://ctrlepiedit.sciencesconf.org/

Very excited to announce the FIRST symposium on epigenome editing! These tools are becoming widely used in mol bio, ag & therapy. It's time to bring leaders together to discuss this rapidly growing and exciting field. And why not in Paris! Please register & share! (1/2) ctrlepiedit.sciencesconf.org

09.03.2026 13:15 👍 78 🔁 55 💬 3 📌 5

PARP inhibitor synthetic lethality reveals homologous recombination sub-pathway architecture https://www.biorxiv.org/content/10.64898/2026.03.06.709881v1

07.03.2026 21:17 👍 5 🔁 2 💬 0 📌 0

🌱 New preprint out on bioRxiv!

How do plants sense seasonal changes in day length?

In our new study, we profiled high resolution (2h) RNA seq time courses in tomato across three photoperiods to uncover how light duration shapes gene expression dynamics.

Summary in next post...

07.03.2026 06:08 👍 16 🔁 6 💬 1 📌 0
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We are celebrating our research institute @cabimer.bsky.social 20th anniversary!! Superb list of speakers!! And attendees!!

06.03.2026 07:45 👍 2 🔁 1 💬 0 📌 0
The nuclease EXO1 promotes genomic instability by degrading nascent DNA in BRCA-proficient cells - Nature Communications DNA repair genes are generally considered tumor suppressors, as they maintain genomic stability. Here, the authors show that the exonuclease EXO1 is overexpressed in a significant proportion of tumors...

Happy to share our new work on the nuclease EXO1, published in Nature Communications. We show that EXO1 is overexpressed in cancers. This promotes nascent DNA degradation, even in BRCA-proficient cells, resulting in genomic instability and chemotherapy sensitization. www.nature.com/articles/s41...

05.03.2026 18:37 👍 10 🔁 5 💬 0 📌 0
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🎓 Registrations are open for the next Post-transcriptional Gene Regulation international course at @institutcurie.bsky.social with international experts, until march 31st 2026.

📆 18-22 may
📍 Institut Curie, Paris
🗒️ More infos on training.institut-curie.org/courses/post...

24.02.2026 10:42 👍 1 🔁 2 💬 1 📌 0

It was a great pleasure to host @fmattiroli.bsky.social in her visit to the @cbm-csic-uam.bsky.social
Wonderful science and discussions!

13.02.2026 20:36 👍 7 🔁 2 💬 1 📌 0
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We are looking for Postdoctoral Fellows with expertise in Structural Biology. Expertise in CryoEM/CryoET is required. Come join us in St. Louis to work on some amazing enzyme complexes.
www.antonylab.org/positions.html

APPLY HERE: slu.wd5.myworkdayjobs.com/en-US/Career...

13.02.2026 02:02 👍 6 🔁 8 💬 0 📌 0
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Dozens of researchers will move to France from US following high-profile bid to lure talent Nature - Large proportion worked at Columbia University, which had its grants cut and frozen by the administration of US President Donald Trump.

Almost all of the scientists were previously at US institutions

go.nature.com/4tzxGX5

14.02.2026 15:16 👍 106 🔁 54 💬 3 📌 3

A beautifully crafted summary of the extraordinary discovery in the lab of my @mrclmb.bsky.social colleague @philholliger.bsky.social of a tiny RNA that can replicate RNA.

12.02.2026 22:52 👍 18 🔁 9 💬 0 📌 0

Y hoy, #11F, las mujeres científicas del #CBM llenan el Auditorio.
¡Y no caben todas!
Como referencia, el 4️⃣0️⃣% de los/las IPs del CBM son mujeres.
@csic.es @uam.es @cbm-csic-uam.bsky.social

11.02.2026 14:55 👍 3 🔁 3 💬 0 📌 0
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Celebramos el #11F con una foto de nuestras compañeras científicas, técnicas, gestoras, etc., en el CBM. 👩‍🔬💫 ¡Por más visibilidad, igualdad y oportunidades para las mujeres en ciencia!
#MujeresYCiencia #diadelamujerylaninaenlaciencia #TodasHacemosCiencia

11.02.2026 16:54 👍 8 🔁 8 💬 0 📌 0
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Events for February 2026 06-07 July 2026 | Munich, GermanyDNA Replication and Its Impact on Genome and Chromatin MaintenanceWe are RepliFate, a European Training Doctoral Network dedicated to understanding how DNA replication...

We go live!!!

Join us Munich July5-7th to hear exciting research on #Replication by leaders in the field

AND !! registration is FREE 🥳 (but mandatory) - we hope to see many in Munich 🍺 @helmholtzmunich.bsky.social

@replifate.bsky.social @epicrossborders.bsky.social

replifate.eu/event/meetin...

09.02.2026 13:29 👍 30 🔁 26 💬 1 📌 1
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Con motivo del #11F abrimos nuestras puertas a las jóvenes científicas 👩‍🔬
Taller práctico en el CBM con alumnas de ESO en colaboración con STEMTalentGirl, guiado por Celia García y Eva Richard.
Acercar la ciencia a las chicas es clave para construir el futuro.

@csic.es @uam.es

06.02.2026 13:54 👍 6 🔁 3 💬 1 📌 1
HMN 2026: How Aging clock reveals molecules that protect against neurodegeneration Aging clock reveals molecules that protect against neurodegeneration: The nervous system in the nematode can be made visible by the formation of fluorescent dyes in neurons and observed...

How Aging clock reveals molecules that protect against neurodegeneration healthmedicinet.com/aging-clock-...

12.02.2026 07:48 👍 3 🔁 2 💬 1 📌 0
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Pre-incision structures reveal principles of DNA nucleotide excision repair - Nature Cryo-electron microscopy structures of nucleotide excision repair complexes reveal the roles of the constituent proteins XPA, XPB, XPC, XPD, XPF, XPG and RPA in DNA bubble formation and excision ...

Our great collaboration with the lab of Wei Yang and Kaoru Sugasawa is now online in Nature. We’re glad we could contribute some cell biology to complement this beautiful structural and biochemical work.

www.nature.com/articles/s41...

12.02.2026 16:09 👍 23 🔁 12 💬 3 📌 1
A group of about 30 people pose together in a bright office space.

A group of about 30 people pose together in a bright office space.

Today, we’re launching a new company, ALTx Therapeutics. Founded by Simon Boulton, the company will develop the first precision therapies targeting ALT cancers, in partnership with Slingshot Therapeutics Limited and @crhorizons.bsky.social.

Find out more ➡️ www.crick.ac.uk/news/2026-02...

05.02.2026 12:45 👍 20 🔁 7 💬 0 📌 0
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Today is World Cancer Day, but do you know the signs and symptoms of breast cancer?

Get to know your normal by checking your breasts regularly.

Touch your breasts✋

Look for changes👀

Check anything new or unusual with a GP✅

breastcancernow.org/about-breast...

04.02.2026 11:59 👍 2 🔁 4 💬 1 📌 0
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Prevent 2026 PREVENT 2026

Este otoño llega a Madrid #PREVENT2026, workshop sobre predisposición genética y prevención de la leucemia infantil, coorganizado por nuestro investigador César Cobaleda.
📍CSIC – Serrano 117
🗓️25 de septiembre
Info y registro 👉 prevent2026.org

04.02.2026 14:30 👍 2 🔁 3 💬 0 📌 0

🚀 Postdoc opportunity!
Our lab is looking for a candidate to work on tumor drivers in BRCA2‑mutated cancer.
If you're interested in applying, feel free to email me or send a DM! DEADLINE March 30th eacr.org/eacr-fellows...

04.02.2026 08:28 👍 1 🔁 0 💬 0 📌 0
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Please note that the zoom link for tomorrow's webinar with @nitikataneja.bsky.social and @doksanilab.bsky.social has been updated:
uzh.zoom.us/j/6466274666...

02.02.2026 22:26 👍 9 🔁 3 💬 0 📌 0
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DNA-protein cross-links promote cGAS-STING–driven premature aging and embryonic lethality DNA-protein cross-links (DPCs) are highly toxic DNA lesions that block replication and transcription, but their impact on organismal physiology is unclear. We identified a role for the metalloprotease...

Our Science paper is out! 😃

www.science.org/doi/10.1126/...

01.02.2026 12:29 👍 38 🔁 18 💬 0 📌 0

Please repost and consider applying: we work in such a fantastic context, we ask so interesting questions, and we have such a collegial and best-willing atmosphere… CRBM = Happy & Good Science

30.01.2026 23:49 👍 10 🔁 9 💬 0 📌 0
International Symposium on Chromosome Dynamics from Structure to Cellular Function

Happy to share the “International Symposium on Chromosome Dynamics: from Structure to Cellular Function” that will be held in Japan 31st of May 2026 www.fbs.osaka-u.ac.jp/labs/fukagaw.... Registrations will open on December 1st! Plenty of opportunities to present your work! Hope to seeing you

21.11.2025 18:33 👍 9 🔁 5 💬 0 📌 2
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📚📢 Ha salido el nuevo Catálogo de Conferencias Científicas del @csic.es para centros educativos y entidades en Madrid. El CBM ofrece 17 charlas divulgativas sobre biología, cáncer, inmunología, virología, biotecnología y más. ¡Solicita la tuya! 👩‍🔬👨‍🔬
🔗 delegacion.madrid.csic.es/catalogo-con...

15.01.2026 15:44 👍 9 🔁 8 💬 0 📌 0
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A study in @science.org from Paul Cohen's lab, led by @maschakoenen.bsky.social, demonstrates how beige fat directly influences blood pressure. The findings offer a new target for treating vascular disease and could lead to more precise therapies for hypertension: https://bit.ly/4pK0hGh

15.01.2026 20:07 👍 19 🔁 5 💬 0 📌 1