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Valentin Rodionov

@arbitraryeffect

Chemist. Neurodivergent. Orcophobe. Hand-tool woodworker. Faculty @ CWRU Macro. Lab website: rodionovlab.org

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Latest posts by Valentin Rodionov @arbitraryeffect

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A Unique Situation for UniQure

This story (UniQure) is a mess, thanks to the Trump-era FDA, and it’s not over yet:

10.03.2026 20:14 πŸ‘ 23 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
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Finished AJCR's 2023 volume. Found about 76 papers with concerning images, only using ImageTwin (w/o looking for anything else). The editorial board (including @weldeiry.bsky.social) must be so proud.

10.03.2026 21:33 πŸ‘ 9 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
PubPeer - Search publications and join the conversation. PubPeer enables scientists to search for their publications or their peers publications and provide feedback and/or start a conversation anonymously.

PSA: When seeing a bold claim like this, always look up if the original article is already flagged and discussed by experts on pubpeer.com

Have not checked this one. Science is cool. But something tells me this is not as breakthrough as claimed.

10.03.2026 18:17 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
FDA NEWS RELEASE
FDA Takes Action to Make a Treatment Available for Autism Symptoms
β€’ More Press Announcements
Feedback
For Immediate Release:
September 22, 2025
The U.S. Food and Drug Administration today initiated the approval of leucovorin calcium tablets for patients with cerebral folate deficiency (CFD), a neurological condition that affects folate (a vitamin essential for brain health) transport into the brain. Individuals with cerebral folate deficiency have been observed to have developmental delays with autistic features (e.g., challenges with social

FDA NEWS RELEASE FDA Takes Action to Make a Treatment Available for Autism Symptoms β€’ More Press Announcements Feedback For Immediate Release: September 22, 2025 The U.S. Food and Drug Administration today initiated the approval of leucovorin calcium tablets for patients with cerebral folate deficiency (CFD), a neurological condition that affects folate (a vitamin essential for brain health) transport into the brain. Individuals with cerebral folate deficiency have been observed to have developmental delays with autistic features (e.g., challenges with social

CN Health
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HEALTH β€’ 5 MIN READ
FDA declines to endorse leucovorin for autism, walking back earlier statements suggesting benefit

CN Health Subscribe HEALTH β€’ 5 MIN READ FDA declines to endorse leucovorin for autism, walking back earlier statements suggesting benefit

Started/Going

This is what happens when snake oil peddling political appointees are installed in leadership positions at HHS.

There was never any credible evidence that leucovorin could treat autism spectrum disorder, and now the FDA has been forced to admit it.

10.03.2026 14:33 πŸ‘ 142 πŸ” 55 πŸ’¬ 8 πŸ“Œ 1
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I'll just leave this here.

papers.ssrn.com/sol3/papers....

10.03.2026 04:29 πŸ‘ 36 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
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I used to waste years preparing gourmet meals. It was creative, an expression of my humanity, and fostered zen.

Thanks to McDonalds, I don't have to do that!

#Satire

10.03.2026 04:02 πŸ‘ 370 πŸ” 67 πŸ’¬ 26 πŸ“Œ 25
Preview
Open Science round-up: Making preprints count - International Science Council In this issue, we feature an editorial by the International Network for Advancing Science and Policy (INASP) on how funders and policy-makers can support a faster, more equitable publishing system by ...

"Funders serious about timely, open, and equitable access to research must explicitly recognize preprint sharing as a route to Open Access compliance"

I know I'm a broken record on this but it seems so blindingly obvious... #PlanU journals.plos.org/plosbiology/...

council.science/blog/open-sc...

10.03.2026 13:17 πŸ‘ 15 πŸ” 12 πŸ’¬ 0 πŸ“Œ 2

Epstein used his ties to Nobel laureate scientists to try to rebuild his image - NPR

10.03.2026 11:49 πŸ‘ 1562 πŸ” 400 πŸ’¬ 58 πŸ“Œ 19

It really is quite grimly hilarious how the drive for "Open Access" in academic publication was almost immediately captured by publishers who declared that, if readers weren't going to pay, then authors and their employers would have to.

And we bought it, schmucks.

10.03.2026 12:02 πŸ‘ 61 πŸ” 19 πŸ’¬ 1 πŸ“Œ 1

My extra radical far loony left position is that no one should ever be allowed to make a profit from academic publishing. It is a public good. See also: education, healthcare (on a good day, public transport…)

10.03.2026 08:42 πŸ‘ 317 πŸ” 81 πŸ’¬ 9 πŸ“Œ 12
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These nuts are not even bothering to disguise their scam. They are now just using AI videos to attempt to spread a vague fear about some "thingy."

Could this actually influence anyone?

+359% scary

10.03.2026 06:11 πŸ‘ 1 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

Editor's Note: They were prophetic.

10.03.2026 04:11 πŸ‘ 92 πŸ” 13 πŸ’¬ 5 πŸ“Œ 1
PubPeer - Search publications and join the conversation. PubPeer enables scientists to search for their publications or their peers publications and provide feedback and/or start a conversation anonymously.

Not my direct field - but a lot of his work from the 90s-00s makes its appearance on PubPeer. Unfortunately, most (if not all) of the highlighted concerns appear valid. That has failed to embarrass him. Associating with "MAHA" won't either.
It's sad.

pubpeer.com/search?q=el-...

10.03.2026 02:04 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

The reductions in the number of new and competing renewal R01s by topic (based on simple searches in NIH Reporter).

The cuts are across the board: Cancer down 24%, Alzheimer down 45%, Obesity down 29%, Child by 21%.

Transgender was down by 84% but represents only a small number of grants.

09.03.2026 18:25 πŸ‘ 44 πŸ” 27 πŸ’¬ 1 πŸ“Œ 6

Putin is helping Iran.

Zelenskyy is helping us.

Trump does not seem to understand or is ignoring these basic facts.

Hope someone on his team will help the president correct this policy position and...

Thank Zelenskyy.
Arm Ukraine.
Sanction Putin.

09.03.2026 15:44 πŸ‘ 1353 πŸ” 520 πŸ’¬ 100 πŸ“Œ 26

An inappropriate relationship at Ohio State?
*shakes head*
No, it's THE inappropriate relationship

09.03.2026 14:10 πŸ‘ 704 πŸ” 93 πŸ’¬ 26 πŸ“Œ 8

Congratulations, if you've ever made a BOFA DEEZ NUTS joke, you probably also had a better understanding of how Trump would impact the economy than Bank of America's actual head of US Equity & Quantitative Strategy.

09.03.2026 13:19 πŸ‘ 392 πŸ” 45 πŸ’¬ 11 πŸ“Œ 1

People did argue Eliza was self-aware. And it was just about 200 lines of code. en.wikipedia.org/wiki/ELIZA#R...

09.03.2026 02:43 πŸ‘ 267 πŸ” 65 πŸ’¬ 14 πŸ“Œ 11
Preview
Scientific Reports 2025: A Year in Review β€œIn this blog I write about papers published by Scientific Reports in 2025, so we could consider it to be a sort of β€œwrap-up” of highlights and special achievements in the world&#…

Peer review at a respectable journal, who are we to question it?
forbetterscience.com/2026/01/06/s...

09.03.2026 11:52 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Just read the abstract 🫠 via Alexander Magazinov. I don't believe he is on Bluesky.

09.03.2026 11:00 πŸ‘ 119 πŸ” 25 πŸ’¬ 14 πŸ“Œ 50

Next post clarifies that it was Cr(VI). Which is not so good. Cr(III) compounds are often pretty inert and can be quite insoluble, but the higher oxidation state is generally reactive and toxic. . .

09.03.2026 03:28 πŸ‘ 30 πŸ” 6 πŸ’¬ 2 πŸ“Œ 1

I'll just block and let it scream into the void.

09.03.2026 04:13 πŸ‘ 2 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

No, you did not bring her up.
You came to the thread that discusses the reasons for why there are a lot of negative posts about the Harris campaign lately.
You stated that she ran a bad campaign. According to you, that's the reason. I think bots. We can agree to disagree.

09.03.2026 04:10 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

No, but that had nothing to do with her campaign such as it was.
Not her fault, not her campaign's fault.
If someone was "on the fence" regarding the choice in 2024, no campaign could have swayed them. It is a definition of irrationality.

09.03.2026 04:06 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

I preprint all I publish.
Head on to ChemRxiv, and feel free to post any issues you find on PubPeer.

09.03.2026 04:01 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

No, I observe the patterns in the quantity of specific types of posts.
Note that I have not attacked you personally. And you still have not explained how the Harris campaign was so bad it is worth bringing it up with all that is happening now.

09.03.2026 04:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

It's a good thing you *did* vote for her.
But what exactly was so unusually bad about her campaign?

Most accounts speaking out now are indeed bots. The wave started as soon as the tide started turning against the fash.

09.03.2026 03:52 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Let me guess... Genocide?

09.03.2026 02:46 πŸ‘ 1 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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08.03.2026 06:02 πŸ‘ 67 πŸ” 30 πŸ’¬ 8 πŸ“Œ 0
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Is this the correct way to do a corrigendum?

I was tagged in a post (buff.ly/7FdohBx) about a paper (published in Kybernetes, which is published by Emerald Publishing) that had used text from previous papers and a corrigendum had been issued, which said:
🧡

08.03.2026 16:04 πŸ‘ 7 πŸ” 2 πŸ’¬ 2 πŸ“Œ 0