Trending
erik's Avatar

erik

@fleischel

UVA Neuroscience PhD Candidate training in the Sontheimer Lab // Modeling Astrocyte Heterogeneity in Disease

35
Followers
60
Following
34
Posts
09.02.2025
Joined
Posts Following

Latest posts by erik @fleischel

Post image

Version 0.14.0 of rapids_singlecell has been released! Super cool to see my work was able to help contribute to the addition of the wilcoxon rank-sum test to rank_genes_groups() :)

Stop spending so much time waiting for your analyses to run and start using gpu-accelerated workflows today!

02.02.2026 19:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

hopefully PR is merged soon but it’s encouraging to see other users excited about it :)
reference != rest is still a WIP tho..

14.11.2025 15:11 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

presenting a gpu-accelerated version of the wilcoxon rank-sum test for scanpy / rapids-singlecell’s rank_genes_groups tomorrow.
excited (and nervous) to show my work in a purely computational space for the first time! :)

25.09.2025 02:19 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Post image Post image

'A functional perspective on astrocyte heterogeneity'

by Wookbong Kwon, Michael Williamson & Benjamin Deneen

www.cell.com/trends/neuro...

11.09.2025 12:48 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 1

after the claude code integration i can say zed is the best code editor, hands down.

03.09.2025 23:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Preview
Israel is committing genocide in Gaza, scholars' association says The world's leading genocide scholars' association has passed a resolution saying that the legal criteria have been met to establish Israel is committing genocide in Gaza, its president said on Monday.

"Israel’s policies and actions in Gaza meet the legal definition of genocide in Article II of the United Nations Convention for the Prevention and Punishment of the Crime of Genocide (1948)".
Israel is committing genocide in Gaza, genocide scholars' association says - www.reuters.com/world/middle...

01.09.2025 09:50 πŸ‘ 1785 πŸ” 915 πŸ’¬ 44 πŸ“Œ 64

today i learned @hf.co hosts scVI models. healthy ref AstroWRLD coming soon ℒ️

29.08.2025 08:43 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

benchmark everything :)

26.08.2025 23:20 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Promoting (your) research β€œI am a scientist focused on conducting research, not on promoting it.” This thinking strongly resonated with me when I was a PhD student. If it resonates with you, read on to learn why…

promote [good] research. this was a nice, quick read but has some great points that i’m going to keep in mind as i work on establishing myself in the field and to you all..

blog.slavovlab.net/2020/07/15/p...

25.08.2025 13:09 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image
17.08.2025 07:34 πŸ‘ 2603 πŸ” 578 πŸ’¬ 33 πŸ“Œ 16
Preview
GitHub - scverse/rapids_singlecell: rapids_singlecell: GPU-accelerated framework for scRNA analysis rapids_singlecell: GPU-accelerated framework for scRNA analysis - scverse/rapids_singlecell

you’re telling me I don’t have to wait 45 minutes for tl.umap() to run? …
rapids_singlecell is amazing if you’re working with large datasets
github.com/scverse/rapi...

23.08.2025 10:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
I’m an award-winning mathematician. Trump just cut my funding. The β€œMozart of Math” tried to stay out of politics. Then it came for his research.

I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...

18.08.2025 15:45 πŸ‘ 792 πŸ” 325 πŸ’¬ 20 πŸ“Œ 32

Policing and punishment don't solve homelessness – they make it worse.

17.08.2025 23:50 πŸ‘ 810 πŸ” 190 πŸ’¬ 16 πŸ“Œ 6

we need to stop anthropomorphizing llms. β€œmodel welfare” is hilarious as a concept and openai is now more focused on making chatgpt a friend rather than what it is, a tool.

16.08.2025 09:22 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

the lion understands the importance of having both wet and dry lab expertise, but the lion loves to complain about wet lab

11.08.2025 11:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

looking for collaborators in building an atlas / database of astrocyte heterogeneity in health & disease

11.08.2025 01:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

shoutout to my hpc for enabling me to work on 1M+ cell datasets, but still, an hour to embed the umap.. time to start learning gpu integrations in the scanpy workflow

11.08.2025 01:18 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

All the more power to those who don’t want to use it, but to say it doesn’t have any utility is simply untrue

08.08.2025 01:15 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

A noticeable step up in code generation and organization, though. Thorough repos generated from one prompt.

08.08.2025 01:08 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Wanted to test it by having it suggest nuclei isolation strategies and it thinks I’m interested in making biological weapons or things of that nature

08.08.2025 01:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

GPT-5 is impressive but I don’t enjoy it accusing me of violating ToS..

08.08.2025 00:55 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

credentialism ruins science.

04.08.2025 10:21 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Video thumbnail

Video 2 = Drill following the path plotted by the probe.
Cranial window implantation in mice can be highly variable. This makes it less so.

03.08.2025 17:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Video thumbnail

Demo of a surgery robot that was adapted from www.nature.com/articles/s41...
Video 1 = Limit switch + probe to detect the surface of the skull

03.08.2025 17:39 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
Post image
03.08.2025 15:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

One must imagine Sisyphus happy (I post this after every botched astrocyte immunopanning)

30.07.2025 10:31 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

theory of games and astrocyte behavior..

20.07.2025 08:05 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Post image

radar plots are nice for showing differences in astrocyte transcriptional profiles :) #rnaseq #astrocyte

05.07.2025 15:50 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
a man in a purple jacket is holding a purple object in his hand . ALT: a man in a purple jacket is holding a purple object in his hand .
01.07.2025 22:53 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models o...

out now :) onlinelibrary.wiley.com/doi/10.1111/...

30.06.2025 17:26 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0