Hugo Peluffo's Avatar

Hugo Peluffo

@hugopeluffo

Scientist and University teacher at Universitat de Barcelona. Microglia, macrophages, immunometabolism, phagocytosis, neuroscience, neuroimmune interactions, immune receptors, aging, Alzheimer's...

229
Followers
479
Following
3
Posts
28.11.2024
Joined
Posts Following

Latest posts by Hugo Peluffo @hugopeluffo

An excellent piece by Joachim Frank, 2017 Nobel Laureate in Chemistry, about how we must resist the Trump Administration's crackdown on universities.

www.usnews.com/opinion/arti...

12.10.2025 15:47 πŸ‘ 10 πŸ” 9 πŸ’¬ 0 πŸ“Œ 1

What happens in England is unlikely to stay in England

10.10.2025 16:26 πŸ‘ 132 πŸ” 18 πŸ’¬ 6 πŸ“Œ 0
Video thumbnail

CHICAGO β€” Outside an elementary school during dismissal… horrifying. What have we become?

09.10.2025 14:34 πŸ‘ 17315 πŸ” 10231 πŸ’¬ 2803 πŸ“Œ 1830
Post image

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...

09.10.2025 18:06 πŸ‘ 344 πŸ” 103 πŸ’¬ 12 πŸ“Œ 20
Preview
GLP-1 physiology in obesity and development of incretin-based drugs for chronic weight management - Nature Metabolism Holst reflects on the development of GLP-1-based drugs for the therapy of obesity, from early observations to remarkable results in more recent clinical trials, discussing physiological, pharmacological and clinical considerations related to their use.

#Throwback πŸ§ͺ

REVIEW | GLP-1 physiology in obesity and development of incretin-based drugs for chronic weight management

Jens J Holst

07.10.2025 18:01 πŸ‘ 8 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0
Preview
Varicella-zoster virus reactivation and the risk of dementia - Nature Medicine Large-scale longitudinal health records reveal consistent association of varicella-zoster virus reactivation with dementia.

A new Nature Medicine study analyzing health records from >100 million people in the US offers compelling evidence that reactivation of varicella-zoster virus (VZV) ,the same virus that causes chickenpox and shingles may contribute to dementia risk.
www.nature.com/articles/s41...

06.10.2025 16:46 πŸ‘ 215 πŸ” 84 πŸ’¬ 7 πŸ“Œ 9
Preview
Jane Fonda relaunches free speech group started by her father during the McCarthy era In wake of the Trump administration’s censorship threats, the actor re-established the Committee for the First Amendment with A-list support

. @janefonda.com is so inspirational

www.theguardian.com/film/2025/oc...

03.10.2025 01:31 πŸ‘ 4506 πŸ” 1036 πŸ’¬ 68 πŸ“Œ 50
"… Goodall’s … is a story of genuine scientific curiosity, determination, and respect for
nature and humanity …" H. Holden Thorp, Editor-in-chief, Science journals

"… Goodall’s … is a story of genuine scientific curiosity, determination, and respect for nature and humanity …" H. Holden Thorp, Editor-in-chief, Science journals

Jane Goodall has died at the age of 91.

In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8

01.10.2025 19:13 πŸ‘ 175 πŸ” 47 πŸ’¬ 4 πŸ“Œ 5
Video thumbnail

I was back at 26 Federal Plaza today, where an ICE agent violently threw this bereft woman to the ground in front of her kids. She had not touched him. She did not pose any threat. She had to be taken to the hospital. (πŸŽ₯: Elias Eliahu)

25.09.2025 18:03 πŸ‘ 28048 πŸ” 14019 πŸ’¬ 5700 πŸ“Œ 4027
Post image

Our manuscript showing that the microglia/macrophage CD300f immune receptor is important for in vivo sensing of DAMPs/tissue damage is out doi.org/10.1016/j.bb.... CD300f participates in efferocytosis and apoptotic cell metabolization. We also show that its absence potentiates brain damage after TBI

18.09.2025 08:03 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
Preview
Equity in science is a beautiful lie β€” and I’m done pretending Science isn’t really moving towards equity; institutions are just perfecting the appearance of equity. We need to build an alternative system.

A sad reality… gaslighting and performative actions are still the norm.

16.09.2025 19:17 πŸ‘ 6 πŸ” 4 πŸ’¬ 0 πŸ“Œ 0
Post image

Education is the enemy of fascism.

16.09.2025 18:09 πŸ‘ 27224 πŸ” 8281 πŸ’¬ 1601 πŸ“Œ 517
Preview
U.N. commission finds that Israel committed genocide in Gaza Israel rejected the conclusions, which echo those of a growing group of governments and human rights organizations.

An independent United Nations commission said that Israel was committing genocide in Gaza.

The commission found indications of intentions to destroy, in whole or in part, Palestinians in the Gaza Strip as a group β€” which it said amount to genocide.

16.09.2025 19:30 πŸ‘ 122 πŸ” 54 πŸ’¬ 8 πŸ“Œ 12
Preview
Gov. Greg Abbott pardons Daniel Perry, veteran who killed police brutality protester in 2020 A Travis County jury sentenced Perry to 25 years in prison last year, prompting Abbott to ask the state parole board to review his case.

I am just going to keep posting that the TX governor recently pardoned a political murderer.

The dude texted "I'm going to shoot protestors", then went and shot a Black Lives Matter protester. He was convicted in a jury trial.

Hard to find a more blatant example of celebrating political violence.

15.09.2025 18:56 πŸ‘ 8230 πŸ” 4011 πŸ’¬ 99 πŸ“Œ 118

This is exactly what us, scientists, should do with scientific organizations implicated in the genocide. Here is a list of them: bdsmovement.net/academic-boy...

12.09.2025 21:29 πŸ‘ 2 πŸ” 1 πŸ’¬ 2 πŸ“Œ 0
Side-by-side images of Banksy’s mural on the Royal Courts of Justice in London. On the left, the artwork appears faded and scrubbed, leaving only a ghostly outline of a judge raising a gavel over a protester holding a placard. On the right, the mural is fully visible in sharp black and white stencil, showing a judge in a traditional white wig and robes striking down at a protester who defends himself with a bloodied sign.

Side-by-side images of Banksy’s mural on the Royal Courts of Justice in London. On the left, the artwork appears faded and scrubbed, leaving only a ghostly outline of a judge raising a gavel over a protester holding a placard. On the right, the mural is fully visible in sharp black and white stencil, showing a judge in a traditional white wig and robes striking down at a protester who defends himself with a bloodied sign.

They erased the new Banksy mural in London. But the stain remains.

10.09.2025 11:02 πŸ‘ 4584 πŸ” 1397 πŸ’¬ 126 πŸ“Œ 395
Post image

Jeffrey Epstein’s estate has given Congress a copy of the 2003 birthday book, including the letter with Trump’s signature that he has said doesn’t exist.

Read more: πŸ”— on.wsj.com/4nGGdnJ

08.09.2025 19:07 πŸ‘ 1914 πŸ” 662 πŸ’¬ 105 πŸ“Œ 205
Preview
Joseph McNeil, Young Spark in a Civil Rights Battle, Dies at 83

'On the afternoon of Feb. 1, 1960, Mr. McNeil and three classmates from what is now North Carolina A&T State University in Greensboro approached the whites-only lunch counter at Woolworth’s, sat on the turquoise- and salmon-colored vinyl seats and nervously ordered coffee.'

06.09.2025 01:36 πŸ‘ 31 πŸ” 14 πŸ’¬ 1 πŸ“Œ 2
Post image

How is this not a screaming massive headline across every news site? This is insane, a virtual declaration of civil war. We fought a revolution to not be subjected to this kind of tyranny

06.09.2025 17:07 πŸ‘ 3360 πŸ” 817 πŸ’¬ 134 πŸ“Œ 107
Video thumbnail

KASIE HUNT: Over the summer you said, β€œThere’s no vaccine that’s safe and effective”. Do you still believe that?

RFK JR: β€œI never said that.”

KASIE HUNT: β€œPlay the clip.”

RFK JR (clip): β€œThere’s no vaccine that is safe and effective.” (March 2024)

ht: @cwebbonline.com

02.09.2025 19:40 πŸ‘ 15603 πŸ” 4441 πŸ’¬ 1052 πŸ“Œ 659

Yes, it was carefully hidden in the New England Journal of Medicine.

Pfizer/BioNTech vaccine (www.nejm.org/doi/pdf/10.1... )

1/2

01.09.2025 16:08 πŸ‘ 2841 πŸ” 829 πŸ’¬ 76 πŸ“Œ 49
Preview
RFK Jr. Must Go. And He's Not the Only One.

@dereklowe.bsky.social continues to write some of the most important views on what is happening to US science and public health: www.science.org/content/blog...

28.08.2025 19:54 πŸ‘ 12 πŸ” 5 πŸ’¬ 0 πŸ“Œ 0
Preview
Unraveling the arc of vaccine progress The philosopher Thomas Hobbes famously described life in 1651 as β€œnasty, brutish, and short.” He was undeniably correct, with estimates of average life expectancy in the UK at the time ranging from 37...

"This is not the future the American public desires or deserves."β€”Seth Berkley @science.org
www.science.org/doi/10.1126/...

28.08.2025 18:34 πŸ‘ 368 πŸ” 112 πŸ’¬ 4 πŸ“Œ 6
Two hummingbirds face each other while flying , beaks are within millimeters of each other . The one on the right appears to be flying away or the one on the left appears to be hovering over it and reaching out with its feet

Two hummingbirds face each other while flying , beaks are within millimeters of each other . The one on the right appears to be flying away or the one on the left appears to be hovering over it and reaching out with its feet

Department of Hummingbird War. πŸͺΆ

27.08.2025 18:57 πŸ‘ 731 πŸ” 131 πŸ’¬ 22 πŸ“Œ 6
Graph showing wildfire carbon emissions in Spain. This year's fires are in a league of their own.

Graph showing wildfire carbon emissions in Spain. This year's fires are in a league of their own.

This summer's raging wildfires in Spain are the red spike in this graph. atmosphere.copernicus.eu/copernicus-i...

19.08.2025 16:33 πŸ‘ 23 πŸ” 19 πŸ’¬ 1 πŸ“Œ 1
Post image

Review of the possible role of Matzinger's "danger theory" of damage-associated molecular patterns in CNS as drivers of increased incidence of major depressive disorder www.science.org/doi/10.1126/...

25.07.2025 20:46 πŸ‘ 11 πŸ” 9 πŸ’¬ 0 πŸ“Œ 0

It’s not hidden and never has been.

24.07.2025 14:23 πŸ‘ 55 πŸ” 38 πŸ’¬ 7 πŸ“Œ 0
Post image

PhD and Postdocs! Don’t miss this opportunity :)
Apply for the CAJAL Advanced Neuroscience Training Course on Neuroimmunology in Bordeaux!
Fantastic line-up and hands-on training in cutting-edge techniques.
Deadline: July 21, 2025!

cajal-training.org/on-site/neur...

02.07.2025 21:53 πŸ‘ 4 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0
Preview
Trump team axes contracts with publishing giant Springer Nature The action comes as high-ranking US officials criticize top journals as β€˜woke’ and β€˜corrupt’.

Trump team axes contracts with publishing giant Springer Nature

At first, NIH told me its contracts with SN were active and that they help β€œadvance scientific discovery”.

Hours later, HHS said the opposite: "Precious taxpayer dollars should not be used on unused subscriptions to junk science.”

30.06.2025 20:36 πŸ‘ 356 πŸ” 203 πŸ’¬ 17 πŸ“Œ 67