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Matt Wynia

@mattwynia

ID doc. Dad. Ethics in disasters, which is a lot lately. Professor of medicine and of public health. Posts mine, not my employer’s.

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30.07.2023
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Latest posts by Matt Wynia @mattwynia

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Exclusive | Trump Sons Back New Drone Company Targeting Pentagon Sales Powerus says it plans to acquire Ukrainian drone technology to sell to the U.S. military.

Definition of COI: "The deal brings deeper involvement by the Trump family into a multibillion-dollar sector that has new opportunities for growth following changes imposed by the Trump administration."
www.wsj.com/politics/nat...

09.03.2026 16:03 👍 0 🔁 0 💬 0 📌 0
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Opinion | This Is the Moment Adam Smith Has Been Waiting For

"Smith directed his strongest ire against...mercantilism, which measured success by hoarded gold and trade surpluses, not by human well-being. It benefited special interests at the expense of the public..." www.nytimes.com/2026/03/09/o...

09.03.2026 13:51 👍 1 🔁 0 💬 0 📌 0

Good point. There are no perfect heroes.

09.03.2026 13:39 👍 1 🔁 0 💬 0 📌 0
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Novo Nordisk's Wegovy and Ozempic shots could be made for as little as $3 a month, analysis finds Generic versions of Novo Nordisk’s Wegovy and Ozempic medications could be mass produced for about $3 per person a month, according to a new analysis.

'...researchers estimated a generic version of semaglutide...could be made for $28 to $140 per person a year and then sold at low prices once patents expire this year in several countries." www.statnews.com/pharmalot/20... via @statnews.com

09.03.2026 13:24 👍 0 🔁 0 💬 0 📌 0
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Opinion | George W. Trump Goes to War

“…the idea that America can go into a rough neighborhood, hit our enemies hard, kill some of their leaders and force them to RESPECT OUR HEGEMONY is not some brilliant innovation…”
www.nytimes.com/2026/03/07/o...

08.03.2026 15:32 👍 1 🔁 0 💬 0 📌 0
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Pete Hegseth’s Moral Unseriousness The defense secretary appears unable to approach matters of life and death with even the slightest bit of reverence or humility.

“Eisenhower and Lincoln were rarities… But their standards—the virtues they revered, the human sympathies they never allowed to narrow—are ones we need to celebrate and to guard against those who would subvert them.”
www.theatlantic.com/politics/202...

08.03.2026 14:26 👍 0 🔁 0 💬 1 📌 0
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Vinay Prasad, key Makary ally and a focus of controversy at the FDA, is leaving the agency Prasad has been involved in several controversial decisions related to rare disease treatments.

But is he really?

www.statnews.com/2026/03/06/f... via @statnews.com

06.03.2026 22:53 👍 1 🔁 0 💬 0 📌 0
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Stark Divide: Americans More Confident in Career Scientists at U.S. Health Agencies Than Leaders | The Annenberg Public Policy Center of the University of Pennsylvania When it comes to reliable health information, Americans are more confident in federal health agencies' career scientists than their leaders.

“On vaccinating newborns for hepatitis B, Americans say they are more likely to accept the advice of the American Academy of Pediatrics than the CDC by nearly a 4-1 margin.”
www.annenbergpublicpolicycenter.org/stark-divide...

06.03.2026 13:15 👍 0 🔁 0 💬 0 📌 0
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Despite Promises, Veterans Affairs Department Cut Thousands of Roles for Doctors and Nurses

Heckuva time to cut 5% of VA healthcare jobs, just as you choose to start a war across the Middle East…
www.nytimes.com/2026/03/03/u...

03.03.2026 15:07 👍 0 🔁 0 💬 0 📌 0
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Tennessee woman says hospital canceled her sterilization surgery while admitted to hospital The woman said she had been seeking a salpingectomy — a surgery that removes the fallopian tubes — after years of trying other birth control options.

"... the decision came only after she was already hours into the pre-surgical process... [and] after pre-paying for the surgery, she now is waiting on a refund following the cancellation..."

www.wsmv.com/2026/02/26/t...

27.02.2026 15:49 👍 0 🔁 0 💬 0 📌 0
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Opinion | America, We Have a Math Problem

“Why even bother arguing with a recent claim by Mr. Trump’s Department of Homeland Security implying that it could deport 100 million people, approximately double the total number of immigrants in the entire country?”
www.nytimes.com/2026/02/26/o...

27.02.2026 01:20 👍 0 🔁 0 💬 0 📌 0
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C.D.C.’s New Acting Director Draws Unexpected Praise From Agency Staff

This is how low its gone: he just has to say he’ll support vaccination for measles and suddenly he’s a breath of fresh air. Sigh.
www.nytimes.com/2026/02/26/h...

26.02.2026 23:04 👍 2 🔁 0 💬 0 📌 0

Before vaccines, the mortality rate for Diptheria was ~30%,
mortality from H flu meningitis was ~5%,
mortality from Meningococcal meningitis was ~12%,
and mortality from tetanus was ~100%.

I sincerely hope his kids don't get any of these vaccine preventable diseases.

25.02.2026 22:45 👍 0 🔁 0 💬 0 📌 0
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Surgeon general nominee and senator face off over vaccines and ‘shared decision-making’ Casey Means wanted to talk about chronic disease. But Bill Cassidy wanted to hear about her views on vaccines.

There is overwhelming evidence of no link between vaccines and autism, but Cassie Means says, "I think it’s important to just keep it [the possiblity of a link] on the table.”

Why? It's a classic Merchants of Doubt tactic & she's selling something.
www.statnews.com/2026/02/25/c... via @statnews.com

25.02.2026 22:33 👍 0 🔁 0 💬 0 📌 0
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15 States Sue H.H.S. Over Revisions to Vaccine Schedule

“Copying Denmark’s vaccine schedule without copying Denmark’s health care system doesn’t give families more options — it just leaves kids unprotected from serious diseases,”
www.nytimes.com/2026/02/24/h...

25.02.2026 16:40 👍 0 🔁 0 💬 0 📌 0

The first of two special issues from the NCHED team has been published in the Journal of the American College of Dentists!

🦷🦷🦷🦷🦷🦷🦷🦷🦷

NCHED has been working for two years to shine a light on work being done at the intersection of humanities & ethics in dentistry.

commons.ada.org/cgi/viewcont...

19.02.2026 15:54 👍 3 🔁 1 💬 1 📌 0
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Fears of polio resurgence as US vaccine adviser questions need for childhood shots Survivors say US healthcare system not ready for new cases – ‘the only thing to fix polio is the polio vaccine’

The polio vaccine has “absolutely been a victim of its own success...People aren’t scared of polio any more... People don’t really see the daily side of living with a vaccine-preventable disease...and that’s the problem.”
www.theguardian.com/us-news/2026...

23.02.2026 20:30 👍 0 🔁 0 💬 0 📌 0
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T.S.A. Says PreCheck Will Remain Operational at Airports

Purely a pressure tactic. I’d bet literally everyone in DHS leadership knows that TSAPre saves time and resources for the Department. Now they’ll have to watch everyone take off their shoes, which will cost DHS more. www.nytimes.com/2026/02/22/u...

22.02.2026 18:51 👍 1 🔁 0 💬 0 📌 0
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Homeland Security to Shut T.S.A. PreCheck and Global Entry at Airports

Its sad that we have to choose between civil rights and easier air travel. But I’ll take the longer line if it means no more masked federal agents dissapearing people off the street based on the color of their skin.
www.nytimes.com/2026/02/22/u...

22.02.2026 15:01 👍 0 🔁 0 💬 0 📌 0
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Denmark Rejects Trump’s Plan to Send Hospital Boat to Greenland

The quips in response to this plan are too easy… www.nytimes.com/2026/02/22/u...

22.02.2026 14:55 👍 0 🔁 0 💬 0 📌 0
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Fat Signing Bonuses, and Concierge Service, for Family Doctors

The rural doctor shortage is bad in Canada, and much much worse in Nigeria, which is where rural Canada is now sourcing new doctors.
www.nytimes.com/2026/02/22/w...

22.02.2026 14:38 👍 0 🔁 0 💬 0 📌 0
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Opinion | Take It From a Doctor: It’s OK if Your Medical Advice Comes From A.I.

“…large language models… can pick up on what information resonates with you most powerfully and expose you to more of it, mistakenly assuming that it’s what you want… like how social media algorithms can encourage doomscrolling.”

NB: That’s a programming choice.
www.nytimes.com/2026/02/17/o...

21.02.2026 14:38 👍 0 🔁 0 💬 0 📌 0
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After leaving WHO, Trump officials propose more expensive replacement to duplicate it HHS proposes spending $2 billion a year to re-create systems the U.S. accessed through the WHO at a fraction of the cost, according to officials briefed on the matter.

Instead of ~700m for influence on and access to massive WHO resources he wants to spend $2b to go it alone, and “certainly accomplish only a fraction of what we did by working together with the entire world.” #Fiscalidiocy
www.washingtonpost.com/health/2026/...

19.02.2026 16:32 👍 0 🔁 0 💬 0 📌 0
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Opinion | ‘Our Patients Are More Frightened and Sicker Than Ever’

"...‘this patient for months was too afraid to leave her home and risk encountering ICE at a clinic or lab. It’s a cruel calculus: seek essential medical care and risk detention, or stay home and risk her life." www.nytimes.com/2026/02/19/o...

19.02.2026 15:36 👍 0 🔁 0 💬 1 📌 0
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Groups sue over Trump effort to ‘erase’ history, science in national parks The coalition behind the lawsuit argues the alterations, or potential changes, at various parks undermine their very purpose to educate and enlighten Americans.

“As Americans, we deserve national parks that tell stories of our country’s triumphs and heartbreaks alike. We can handle the truth.”

www.washingtonpost.com/climate-envi...

17.02.2026 23:59 👍 0 🔁 0 💬 0 📌 0
Declaration of Helskinki, Provision 33: The benefits, risks, burdens, and effectiveness of a new intervention must be tested against those of the best proven intervention(s), except in the following circumstances:
If no proven intervention exists, the use of placebo, or no intervention, is acceptable; or
If for compelling and scientifically sound methodological reasons the use of any intervention other than the best proven one(s), the use of placebo, or no intervention is necessary to determine the efficacy or safety of an intervention; and the participants who receive any intervention other than the best proven one(s), placebo, or no intervention will not be subject to additional risks of serious or irreversible harm as a result of not receiving the best proven intervention.
Extreme care must be taken to avoid abuse of this option

Declaration of Helskinki, Provision 33: The benefits, risks, burdens, and effectiveness of a new intervention must be tested against those of the best proven intervention(s), except in the following circumstances: If no proven intervention exists, the use of placebo, or no intervention, is acceptable; or If for compelling and scientifically sound methodological reasons the use of any intervention other than the best proven one(s), the use of placebo, or no intervention is necessary to determine the efficacy or safety of an intervention; and the participants who receive any intervention other than the best proven one(s), placebo, or no intervention will not be subject to additional risks of serious or irreversible harm as a result of not receiving the best proven intervention. Extreme care must be taken to avoid abuse of this option

Maybe not in FDA guidance directly, but use of best available standard of care as comparator is a core concept in research ethics. E.g., Declaration of Helsinki... Yes, Moderna is arguing they should be able to skirt this rule, but I'm not going to defend that, even to score valid political points.

12.02.2026 21:38 👍 0 🔁 0 💬 1 📌 0
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WHO director-general calls plans for U.S.-funded vaccine trial ‘unethical’ The director-general of the WHO said a U.S.-funded study of the hepatitis B vaccine in Guinea-Bissau would be “unethical” if it proceeds as planned.

“Of course, a sovereign country can decide whatever they want...”
Yes, it's unethical, but I disagree that countries should do unethical trials without cost; otherwise, what's the point of international research ethics standards? www.statnews.com/2026/02/11/h... via @statnews.com

12.02.2026 21:27 👍 0 🔁 0 💬 0 📌 0

All you say is true about Kennedy, AND IMHO it doesn't help our cause to call out a decision that's defensible as though it's not. I'd rather focus on the MANY clear and obvious violations of ethics, research, and practice that are being perpetrated.

12.02.2026 21:06 👍 0 🔁 0 💬 1 📌 0
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Better regulation of industry-sponsored clinical trials is long overdue - PubMed Regulating clinical trials for testing new drugs is fraught with risk. Misregulation can slow development of innovative and useful new drugs, but in other ways misregulation can foster trials that are inefficient and unethical, driven by commercial rather than scientific ends, and that can harm pati …

Actually it's the opposite. FWIW, I'm no fan, and if he were backing placebo-controlled flu vaccine trials, I'd be all over that. But he's arguing for using the best available therapy as control, which is appropriate even though pharma often tries to get out of it.
pubmed.ncbi.nlm.nih.gov/19723252/

12.02.2026 20:29 👍 1 🔁 0 💬 1 📌 0
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Prasad overruled FDA staff to reject Moderna's flu vaccine application The rejection is the latest instance of Vinay Prasad overruling career FDA scientists to place vaccines under harsher scrutiny.

I think it matters that *in this case* he is right that Moderna should not have tested a new flu vaccine in people over 65 by comparing it to a sub-optimal dose of the comparator. These pharma clinical trial shenanigans should be called out.
www.statnews.com/2026/02/11/m... via @statnews.com

12.02.2026 19:59 👍 0 🔁 0 💬 1 📌 0