When someone says „Scientists do not want you to know“ you can dismiss everything from there on. Scientists want you to know. They are desperate that you know. They can’t shut up about what they found out and want you to know.
NEW: The USPS changed its rules on how it postmarks ballots.
This may affect elections at every stage at which there's a mail deadline.
An underplayed one: VOTER REGISTRATION.
Many voters who send in their registration forms by mail could be postmarked late, missing out without realizing it.
Job alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk
Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️🩹
Full info below, and please share! 🫶🏻
bit.ly/467TO0M
If you are a scientist funded by NIH and agree that if the HHS/NIH bill is held hostage by linkage for funding to DHS/ICE, we need to shutdown both and save lives, its time to speak up. Right now, with a few exceptions, the silence is deafening
Portrait picture of a black cat
Black cat sitting on a cat tree looking outside a window towards a bird feeder
Introducing Martino 🐈⬛
It’s not about drugs. If it was, Trump wouldn’t have pardoned one of the largest narco traffickers in the world last month.
It’s about oil and regime change.
And they need a trial now to pretend that it isn’t. Especially to distract from his sinking under Epstein and skyrocketing healthcare costs.
It's kind of like the @nytimes.com just figured this out. It is a serious problem. Keep reporting on it. Gift link:
www.nytimes.com/interactive/...
A lot lot lot of emotions (positive) today but reading the goodbye notes of "your first student" ending in "science desperately needs mentors like you"
People, I'm an emotional South Italian queer person! I'm crying of joy!
1. A landmark study was just published in The Journal of Pediatrics.
It found a 68% reduction in suicidality for trans youth getting HRT.
It also found only 7 of more than 400 stopped taking HRT... and of those that did, 4 still identified as gender-diverse.
Transgender care saves lives.
PSA for people with NIH grant periods starting January 1st (including most NIGMS MIRAs): your RPPR is due Saturday, but they haven’t sent out the usual automated reminders, presumably due to the shutdown
Online now! ModulatingJAK2-STAT3 pathway promotes expansion & maturation of human iPSC-derived myogenic progenitor cells; advancing in vitro generation of skeletal muscle progenitor cells for potential cell therapy applications. https://ow.ly/6qAz50XkBvY
Sanford Burnham Prebys | ISSCR
Scaling back DEI isn’t just a moral setback—it’s a loss of innovation.
Bhalla, Trejo & @marymunson4.bsky.social in Nature Cell Biology: limiting who can participate in science “weakens research capacity and stifles discovery.”
doi.org/10.1038/s415...
RESEARCH PAPER: MYOD represses gene expression from non-E-box motifs
By Nicoletti, Massenet et al., Luca Caputo and Pier Lorenzo Puri
➡️ https://genesdev.cshlp.org/content/39/21-22/1299.abstract
#transcription #trancriptionfactor #epigenetics #muscle #stemcells
All the people “afraid” of Zohran Mamdani are racist as hell.
🚨 NEW ISSUE ALERT!!! 🚨
New Outlook, Review and Research articles online now at Genes & Development.
Click on the link to learn more:
➡️ https://genesdev.cshlp.org/content/39/21-22.toc
Thanks to all co-authors at @sbpdiscovery.bsky.social and our collaborators from UT Southwestern and Università di Ferrara
Functionally treated CD54+ cells are able to engraft and contribute to muscle regeneration with a better efficiency compared to untreated cells.
We were able to purify SMPCs using a single surface marker (CD54/ICAM1) and analyze the cells transcriptionally and functionally.
At transcription level treated cells resemble late fetal stage SMPCs rather than embryonal SMPCs that are usually obtained in vitro
We started the project wondering if modulation of the jak2/stat3 pathway would be efficient in increasing the yield. When we inhibited the pathway after the appearance of PAX3+ cells (D12) we managed to double the amount of PAX7+ cells at D30, both in H9 and hiPSCs derived cultures
📣 The paper is out!!
In this paper we tackled 2 major bottlenecks of cell therapy, namely how to increase the yield of progenitors in vitro and, by serendipity, how to mature them to an higher developmental stage.
#muscle #stemcelltherapy #muscleregeneration
www.cell.com/stem-cell-re...
Adda passà a nuttata
If you introduce a trainee saying "I asked chatGPT..." I agree with the eel.
And ask the pronunciation of their surname, that is basic etiquette for fuck sake.
Galley proofs! 🥳💪🔬🧫
The ISSCR joins the global scientific community in mourning the loss of Nobel Laureate Sir John Gurdon whose enduring influence is woven into the very fabric of stem cell science.
https://ow.ly/BjHT50X8T6q
The email you wish to get before heading out to a conference "I am pleased to say that the reviewers have commented enthusiastically on your revised manuscript"
Stay tuned 🥳😉
Vaccination: Risks and Benefits
Driving is important for our jobs and lifestyles, and the risk is quite low. So is vaccination.
www.nejm.org/doi/full/10....
My quote of the day
The sole and basic source of our strength is the solidarity of workers, peasants and the intelligentsia, the solidarity of the nation, the solidarity of people who seek to live in dignity, truth, and in harmony with their conscience.
Lech Walesa
According to a grant reviewer I have no proven experience on iPSCs 🤷
Resubmission button clicked.
Now some time off. See you all in ~10 days
