Seema

Visited BioAsia2026 Hyderabad, India. Excited to learn about keynote speakers from my lab's research domain being invited, Howard Y. Chang (lncRNAs) and Pushmeet Kohli (AlphaFold). Happy to meet alongwith my students and discuss all things lncRNAs and AI.
#RNA
#Computational
@alphafold.bsky.social

Delighted and honored to get on board nature.com/npjsba/editors
Thanks EiC MK Jolly for the tremendous opportunity and I look forward to working proactively towards being among the ambassadors and contributing to this journal's long-term success.
@natureportfolio.nature.com

Structural basis of long non-coding RNA PVT1 interactions with select mRNAs universal in pan-cancer system: A computational study PVT1 lncRNA can regulate multi-gene expression through diverse mechanisms, one of which is through binding interactions with mRNAs. Our previous study…

Thrilled to announce the publication of our latest research:
www.sciencedirect.com/science/arti...

This entails secondary structural studies on the probable mechanisms of PVT1 binding to multiple mRNAs, common DE coding & non-coding genes across pan-cancer system.
#lncRNA
#RNA
#CancerResearch

🧪
Thought of the day:
Penned by me: "An abstract Abstract doesn't age well". Or does it?
#science
#NobelPrize
#abstract

📣 Don't miss this new Review!

Interplay between RNA-protein interactions and RNA structures in gene regulation

🔓 buff.ly/pu6TpVa

🖊️ @rnaminni.bsky.social

#RBPs #RNA #RNAbiology #RNAbindingproteins #RNAbinding #RNAstructure

#rnabiology
#RNA

Hello RNA world! Any new news?

MtDNA incorporating ribonucleotides and not deoxyribonucleotides increases inflammation. Interesting article:

x.com/davidasincla...

#rnabiology
#rna

RNA-induced PRC2 inhibition depends on the sequence of bound RNA Methyltransferase PRC2 (Polycomb Repressive Complex 2) deposits histone H3K27 trimethylation to establish and maintain epigenetic gene silencing. PRC2 is precisely regulated by accessory proteins, his...

PRC2 inhibition by sequence-specific RNA. Interesting!

doi.org/10.1101/2024...

🧪Intellectuals,
Selection for the prestigious National Academy of Sciences (India) Membership is a joy!
Yours truly, Ph.D, MNASc 😀
Grateful to everyone who have stood by me rock solid in this scenic and transformative journey. Heartfelt Thank you to The National Academy of Sciences, India...

Happy to share our latest paper using machine-learning-QSAR on ChEMBL dataset. We identified and designed novel inhibitors for Acid Ceramidase inhibition in Glioblastoma using SHAP-based mechanistic interpretations. Thankful to proactive Reviewers and Editors.
rdcu.be/exD3a

Interesting, so sharing here:
x.com/nlarusstone/...

It is always mind boggling at how massive @agu.org is every year. This is just one session of the poster room, which changes over twice daily for the duration of the conference. #AGU24

And here I was wondering RNA Capping at the first mention of the word 'cap'...caps impart efficient translation and stability to mRNA... 🤔

The great Matterhorn in all its glory… A classic shot from the Swiss alps, but the light was too good to not click this one.

#bluesky #photography #mountains #nature #landscape #landscapephotography #naturephotography

E.g.?

RNA-mediated double-strand break repair by end-joining mechanisms - Nature Communications Double-strand breaks (DSBs) in DNA are challenging to repair. Here, the authors show that transcript RNAs impact the DSB repair outcomes in human and yeast cells by promoting NHEJ or MMEJ in a sequenc...

RNA-mediated DNA damage repair:
www.nature.com/articles/s41...
#RNAbiology
#RNAsky

#RNABiology
#RNAsky
#tRNA

RNA aficianados,
Just attended my first seminar series at RNA Collaborative - The RNA Institute, SUNY University at Albany yesterday. It is awesome science and a great way to stay updated in everything RNA. Registration is free:
www.rnasociety.org/rna-collabor...
#rnabiology
#rnasky
🧪

Any answers? Looks like this is a ResearchGate question. 😀
#rnabiology
#rnasky
#moleculardynamics

RNA splicing junction landscape reveals abundant tumor-specific transcripts in human cancer Li et al. thoroughly analyzed RNA splicing junctions in 34,775 samples and identified 29,051 tumor-specific transcripts that may serve as cancer driver genes, neoantigens, and circulating biomarkers.

Here is a paper where I would just like to say "Thank you" to the authors.

I thoroughly enjoyed this.

I hope you do too.

#GENESky
#RNAsky
#CANsky
#genomics
#bioinformatics
🧪
🧬💻
🔎 microproteins

www.cell.com/cell-reports...

Is 108 kb Air the longest lncRNA?
Any new champion in this category?🤔
#rnabiology
#rnasky
🧪

#rnabiology

Molecular dynamics aficionados! Which is the most accurate RNA force-field currently?
#rnabiology
#computationalbiology
#rnasky
🧪

Yes, what you really want to do is key when you have lot of time till the day you think of retirement....juggle it with playing it safe. Do the balancing act.

#rnasky

Deers and LncRNAs...
www.nature.com/nsmb/volumes...

#rna
#rnabiology

One of my blue jays standing guard over a piece of dried papaya

Got birds?
Reply or quote this with your pics; we’d love to see them
📷🪶

Easy hai?