Nereo Kalebic

New preprint by @nereokalebic.bsky.social linking progenitor morphology, gene expression and fate, revealing that human basal radial glia morphotypes are transcriptionally distinct and exhibit different cell fate determination 🧪🧠🧬
www.biorxiv.org/content/10.6...

Oh well, we forgot to take a picture altogether at the end of our talks #SfN2025…but we did make sure we had good food to celebrate our love for #radialglia and #astrocytes 😌

Who is coming to #SfN2025?

Join our minisymposium on Monday at 2 pm 😍👇

@nereokalebic.bsky.social and I can't wait to chair this minisymposium bridging most of our dearest research interests!

#radialglia #astrocytes #evolution #Development

Human Technopole awarded grant to create 3D models of rare brain cancer  - Human Technopole Human Technopole researchers Nereo Kalebic and Blagoje Soskic have been awarded $1,319,010 by the Gilbert Family Foundation (GFF) through the Next-Generation NF1 Models Initiative. Their funded projec...

🧠 Can we fight rare brain cancers in a dish? Our @nereokalebic.bsky.social and Blagoje Soskic just won $1.3M from the Gilbert Family Foundation to build the first 3D models of NF1 gliomas, mimicking tumour growth and immune interactions.

humantechnopole.it/en/news/huma...

My group @humantechnopole.bsky.social is searching for a #postdoc to work at the interface between #neurodevelopment and #cancerbiology focusing on neurofibromatosis type 1: careers.humantechnopole.it/job/Postdoc-...

It was a great experience to represent @nereokalebic.bsky.social lab and present our work, linking shape and function in glioblastoma, at the goodbye flat biology conference by @helloeacr.bsky.social

This conference was a source of food for thought and a fantastic networking opportunity

Adducins regulate morphology and fate of neural progenitors during neocortical neurogenesis Ossola et al. show that morphoregulatory adducins (ADD1–3) underlie correct basal progenitor morphology and apical progenitor spindle orientation during mammalian neocortical development. Depletion of...

Insightful @cp-cellreports.bsky.social study by Chiara Ossala @stefaniafaletti.bsky.social @nereokalebic.bsky.social & collaborators establishing adducins as critical regulators of neural progenitor proliferation and fate 🧪🧬🧠

www.cell.com/cell-reports...

Thanks Cedric!

This is a great team work by Chiara Ossola, Nikola Cokorac, Emanuele Capra and @stefaniafaletti.bsky.social with support of Ilaria Bertani, our amazing services and facilities @humantechnopole.bsky.social and in collaboration with Elena Taverna group.

Check out our new paper linking morphoregulatory adducins with neural progenitor proliferation and neurogenesis:

Back from #ISSCR2025, where I showed how cell morphology is a new layer of heterogeneity in glioblastoma and controls clinically relevant features with therapeutic promises.
Grateful for the support from @nereokalebic.bsky.social and @humantechnopole.bsky.social and for exciting new collaborations!

Enormous thanks to @k4tj4.bsky.social for fantastically following the conference at bluesky!

Three amazing days of the #neurogen2025 conference at @humantechnopole.bsky.social in Milan. Many thanks to all the participants, speakers and fellow co-organizers. We heard fantastic talks in #neurodevelopment #brainevolution #cancerneuroscience #neuroimmunology #neurodegeneration #neurodiversity

Very proud of Carlotta Barelli’s talk on our efforts to link glioblastoma stem cell morphology with clinical functions #neurogen2025 @humantechnopole.bsky.social

Looking forward to amazing days of talks&discussions #neurogen25 –Neurodev, evolution, de-& regeneration, organoids &more at @humantechnopole.bsky.social with @r3rt0.bsky.social
Thanks to organisers @nereokalebic.bsky.social @harschnitz.bsky.social Jose Davila-Velderrain,Giuseppe Testa,Elena Taverna

💡 Thinking about a PhD?

✨ Join us on 15 April for the #PhD Open Day at Human Technopole! Explore cutting-edge research, meet our Group Leaders, and discover training opportunities in an international, dynamic environment.

Register now 👉 humantechnopole.it/en/trainings... #phdlife

🌍 This unique conference is your opportunity to engage with leaders in neuroscience, celebrate the diversity of human neurobiology, and explore new synergies.

Scientific organisers: @harschnitz.bsky.social, @nereokalebic.bsky.social, Jose Davila-Velderrain, Giuseppe Testa, Elena Taverna

Bravo Oliver!

Excited to share that IBDM (Institut de Biologie du Développement de Marseille) is expanding its research groups this year! A great place for developmental biology and interdisciplinary research located on the beautiful Marseille-Luminy campus!
Deadline for applications: March 30th, 2025

Evolutionary changes leading to efficient glymphatic circulation in the mammalian brain - Nature Communications The functional consequences of the brain changes during evolution remain unclear. Here, the authors use mathematical modeling and experimental validation to demonstrate a relationship between evolutio...

🧪🧠 Great work from Hiroshi Kawasaki’s lab, showing that efficiency of glymphatic circulation is an important factor determining the evolutionary trajectory of the cerebral hemispheres
www.nature.com/articles/s41...

Interested in using sliced cortical organoids for functional studies? Check out our step-by-step protocol for electroporation!

app.jove.com/t/67598/elec...

By our incredibly skilled technician Annika Kolodziejczyk 🤩

Congratulations to Chiara Ossola for a successful PhD defense - the first in the lab 👏👏👏. Check out our latest preprint for more on Chiara's PhD work: www.biorxiv.org/content/10.1...

🗓️ Mark your calendar: May 19-21, 2025
There will be a great #neurogenomics conference @humantechnopole.bsky.social in Milan (@harschnitz.bsky.social ‬ is one of the organizers). Grateful to have been invited alongside (some joined 🦋 recently):
@silvianeuro.bsky.social @sergiuppasca.bsky.social 1/

Cancer stem cell morphology predicts glioblastoma growth and resistance - Human Technopole Human Technopole researchers have identified adducin-γ (ADD3) as a crucial regulator of glioblastoma cancer stem cell morphology and intercellular bridges between tumour cells. These connections facil...

🔬Our Kalebic group with our @francescoiorio.bsky.social Group identified ADD3 as a key gene driving glioblastoma stem cell shape and tumour connectivity, uncovering growth and therapy resistance

📰Published in Life Science Alliance with support from AIRC

humantechnopole.it/en/news/canc...