Taufiq Rahman

Dr T's Pharm Tunes Dr T teaches pharmacology in the University of Cambridge and a fellow of Murray Edwards College. He has a deep passion for mechanisms of drug action (MODA), drug discovery and equally for music and sk...

youtube.com/@drtspharmtu...

Great to be part of this exciting work led by @profmarciniak.bsky.social

Heartiest congrats and very well deserved

Can't believe i got on a 13:13 train from platform 13!

Functional characterization of the store-operated calcium entry pathway in naked mole-rat cells | Open Biology Naked mole-rats (NMRs, Heterocephalus glaber) are highly unusual rodents exhibiting remarkable adaptations to their subterranean habitat and resistance to developing various age-related diseases such ...

very pleased to see this work about SOCE in naked mole rat in a good home - it was great to have @psalmotoxin.bsky.social on board!
royalsocietypublishing.org/doi/10.1098/...

very happy to see our opinion piece out - sincere apology to many researchers whom we couldn't mention since it was meant to highlight more recent (within last two years) development in the field:

doi.org/10.1016/j.cb...

I am looking for a post doc with structural biology and/protein science background - if you meet the criteria and feel interested, then feel free to drop an application:
www.jobs.cam.ac.uk/job/51116/

Periodic ER-plasma membrane junctions support long-range Ca2+ signal integration in dendrites In neuronal dendrites of both rodents and flies, there are regularly spaced contact sites between the endoplasmic reticulum (ER) and plasma membrane, which function as hubs for regulating Ca2+ homeost...

amazing! feels like 'the nodes of Ranvier' equivalent (well, kind of...)..off course cells need to devise how to use this common bivalent metal ion to achieve signalling specificity (and diversity!)

A job in our EM facility - my experience as a user has been very positive so I think it's a great place to work.

A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors - Nature Communications Gs heterotrimers are considered to be poor providers of free Gβγ subunits. Here, the authors show that—despite this—Gs-derived Gβγ dimers are active transducers of GPCR-initiated Ca2+ signals involvin...

quite intriguing - this quintessential signalling paper establishes Gs-derived Gβγ can also generate IP3-evoked Ca2+ signals through directly activating PLCβ - 'long-overlooked mechanism' indeed gets demystified!

great....
www.nature.com/articles/d41...

many thanks for your kind note, Richard (if I may)...I am a huge admirer of your drawings and paintings

my linkedin profile has been hacked...what a nice day to start with!

wishing you all a happy, peaceful year ahead!

Rac-maninoff and Rho-vel: The symphony of Rho-GTPase signaling at excitatory synapses Synaptic connections between neurons are essential for every facet of human cognition and are thus regulated with extreme precision. Rho-family GTPases, molecular switches that cycle between an act...

I didn't know that a journal named 'Small GTPases' exists until I bumped into this nice phrasing 'Rac-maninoff' - excellent thinking from the 'Tenor' and his group!
www.tandfonline.com/doi/full/10....

📢 Applications for the 2025 Cambridge Amgen Scholars Programme are now open!

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this sort of thing will never age!

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