Free radicals #5: Hydroxyl radical (•OH) is a dangerous free radical. The only defense is preventing its formation as all its reactions are nearly at the same very fast rate. To be 50% effective, a scavenger would have to be at a concentration equal to all of other reacting compounds combined. 🧪
Earlier this year, Microsoft published GraphRAG, an alternative to vector similarity based RAG everyone is using. Goal: can also answer queries like "What were the top 5 most prominent topics in all the documents".
They open-sourced the system, including the prompts to construct the entity graph.
An essay in Nature discusses how it’s an astonishing achievement that all of statistics and much of science depends on probability considering no one’s sure what it is. 🧪
https://www.nature.com/articles/d41586-024-04191-7
Facilitating academia’s shift to Bluesky means integrating sharing links in platforms like PubMed. Let’s create spaces for open, collaborative, and scientific discussions! #Bluesky #ScienceCollaboration #AcademicTwitterMigration
Check out the study here www.pnas.org/doi/10.1073/...
New study reveals MANF enhances #autophagy & #lysosome function, reducing toxic protein clumps and extending lifespan in C. elegans! MANF, mediated by HLH-30/TFEB, shows promise for combating age-related diseases by promoting proteostasis & neuronal health. #Neurobiology #AgingResearch
New research challenges traditional cardiac conduction models! The study reveals non-ohmic conduction and anomalous diffusion of electrical signals in heart tissue, reshaping how we understand signal propagation in disease. #Cardiology #Electrophysiology #Research #Science
Read the paper from Andrea Pedroni, Elanur Yilmaz, et al. here: www.nature.com/articles/s41...
The intracardiac nervous system (IcNS) is the heart’s “little brain,” regulating rhythm autonomously. Diverse cell types control heart rate and function. Future therapies: targeted cell replacement, neurocardiac modulation, and arrhythmia treatments. #Cardiology #IcNS #HeartHealth #Innovation
@weeklyshowpodcast.bsky.social Love the conversation with Jon and @mcuban.bsky.social. I especially loved Mark's take on using AI as a data aggregator with human oversight, and their discussion on the flaws of the US health care system. www.youtube.com/watch?v=bnhx...
Boost muscle growth, recovery & health with cutting-edge research on MYC & gene expression! From fighting sarcopenia in aging to aiding athletes & patients with chronic illness, these insights fuel next-gen therapies for stronger lives. 💪✨ #MuscleHealth #ExerciseScience #Biotech
I'm Erica Baller, PI of the Baller Lab, and I am looking forward to #ACNP2024! Excited to present our recent work linking anxiety to uncinate lesion burden in MS (12/11 Poster Session, #22)!!
www.medrxiv.org/content/10.1...
CPR during cardiac arrest can cause serious injuries: rib/sternal fractures, lung hemorrhages, and organ damage. Devices like LUCAS may increase thoracic injury risks without improving survival. #CPR #MedicalForensics #PatientCare
theautopsybook.com/cpr/
Emerging research reveals an overgrowth of microbes like Streptococcus, Candida, and Cryptococcus in Alzheimer’s patients. Vaccines, good hygiene, oral health, and a healthy lifestyle may reduce risk. Let’s rethink dementia prevention. #Alzheimers #Microbiome #BrainHealth #Prevention
Time is running out! Congress must pass #AED legislation before the year ends. The HEARTS Act & Access to AEDs Act can save lives in schools nationwide. Urge your Senator on the HELP Committee to act now. Take action here www.votervoice.net/mobile/Cardi...
#SuddenCardiacArrest #HeartHealth #Advocacy
@davidasinclair.bsky.social Hey! I’m a big fan of your work and love to see what you’re up to. Are you ever going to post on here?
Where do most cardiac arrests happen? 🏠 Nearly 70% occur at home, yet most homes lack access to life-saving devices like AEDs. It's time to bring awareness to the importance of being prepared where it matters most. #CardiacArrest #HeartHealth #AEDsSaveLives
Did you know you're 9x more likely to have a cardiac arrest than a house fire? 🫀🔥 Fire extinguishers are common, but AEDs are rare—even though most arrests happen at home. It’s time to rethink how we prepare for emergencies! #CardiacArrest #HeartHealth #AEDsSaveLives
Check out Karl Freund’s write-up here www.forbes.com/sites/karlfr...
Is the GPU revolution over? One-shot inferencing hits limits, while techniques like agentic AI and chain of thought reasoning demand 100x more power than today’s GPUs. Cerebras CS3 solves AI’s key challenge: memory bandwidth for advanced reasoning.
#ChainOfThought #AgenticAI #GPU #Cerebras #AI
Check out Karl Freund’s write-up here www.forbes.com/sites/karlfr...
Targeting cancer cells with modified viruses, OVs selectively destroy tumors & boost immune responses. Effective in melanoma, glioblastoma, & more. A future of hope in oncology! #CancerTreatment #OncolyticViruses #HealthcareInnovation
Top: ECG trace from a patient in asystole, showing movement caused by CPR. Bottom: Same ECG with impedance trace (yellow), confirming CPR is being performed. The apparent rhythm in the ECG is 100% artifact from chest compressions, highlighting the importance of artifact removal for accurate rhythm interpretation.
CPR artifact can mask a patient’s true rhythm. This patient is in asystole, but CPR motion creates a rhythm-like trace, confirmed by the impedance trace. Advanced AED tech must separate artifact from real rhythms. How can we refine these algorithms—or do we need to? 🚑 #CPR #AED #Asystole
Read more about the editorial here: www.resuscitationjournal.com/article/S030...
Did you know AEDs can now analyze rhythms during chest compressions? AWC tech reduces interruptions and VF time, but CPR artifacts make rhythm detection tough. Filtering and ML help, but how reliable are they in noisy real-world cases? 🚑 #CPR #Defibrillation #AED #VF #Innovation
