Jamsheer

Complete transport cycle of human XPR1, regulated by InsP8 and KIDINS220 @cp-molcell.bsky.social doi.org/10.1016/j.mo...

Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi Nuclei define eukaryotes, enabling macromolecular compartmentalization and cellular regulation. Each nucleus is believed to contain one or more haploid sets of chromosomes (1N). However, we discovered...

Wow: check it out; these fungi distribute their chromosomes across different nuclei!

Normally each nucleus has a complete set of all chromosomes.

Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi | Science www.science.org/doi/10.1126/...

a penguin wearing a bear hat and a blue sweater is jumping in the air ALT: a penguin wearing a bear hat and a blue sweater is jumping in the air

The next frontier in #autophagy is understanding how it functions across cell types to maintain organismal homeostasis. w/ @moritznowack.bsky.social lab, we present TWO #preprint on cell type spec. autophagy in root hairs‼️ #plantscience www.biorxiv.org/content/10.1... www.biorxiv.org/content/10.1...

TIR1-produced cAMP as a second messenger in transcriptional auxin signalling - Nature cAMP produced by the TIR1/AFB receptors of the main endogenous developmental plant hormone auxin acts as a true second messenger, revising the established paradigm of transcriptional auxin signalling.

and we thought auxin signalling was "kind of solved"..

TIR1-produced cAMP is essential for auxin response (in Arabidopsis thaliana) 🔽

www.nature.com/articles/s41...

A portrait of Daisy Roulland-Dussoix from Wikipedia: https://en.wikipedia.org/wiki/Daisy_Roulland-Dussoix

Do you know Daisy Roulland-Dussoix? She is one of the discoverers of restriction enzymes, who’s findings paved the way for the development of recombinant DNA and cloning technologies. Accordingly, the finding was rewarded with a #NobelPrize. But the prize didn’t go to her.
🧵👇

Preprint alert: We show an unconventional role of plant TORC1 as a master regulator of the phosphate starvation program Congratulations @prakhar9t6.bsky.social 🥳

Thanks to all the collaborators!