Less than 1 week to go until the @nf-co.re Hackathon!🌎Join hundreds of participants for 3 days of development and collaboration with the global @nextflow.io community.
We're delighted to be sponsoring this community event and can't wait to see what you will build together!👏 hubs.la/Q045R9_h0
We have more ideas about how to improve this in the future, without sacrificing resume. But you'll have to stay tuned for those 😊
Other things worth checking are using `scratch` - then only files explicitly listed as an 'output' of a process will be saved back to the work directory.
More extreme: even running Nextflow in 'local' mode in a single task and putting all work dirs in scratch, only copying back final results.
We have nf-boost, a plugin that can delete work directories during a run once no longer needed: github.com/bentsherman/...
That works well, but it breaks `-resume` so it's a bit all-or-nothing. That's why it hasn't made it into core Nextflow yet.
You're not wrong - this is a discussion that comes up often in the #maintainers group in @nf-co.re especially. A compromise has to be made between increased modularity (easier to share + reuse code) vs. increased specificity (better optimisation for a given task).
Say hello to Nallo - our Nextflow pipeline for long-read WGS analysis!👋 It handles both ONT and PacBio data and we’re using this for rare disease and population projects in Sweden. A big team effort by Felix Lenner, Anders Jemt et al.🧬💻 academic.oup.com/bioinformati...
Missed The Bioinformatics CRO webinar?💻 @ewels.bsky.social shared how the reproducibility crisis in bioinformatics sparked the creation of @nextflow.io and
@nf-co.re, and why it matters for your scientific workflows.
Watch now ⬇️
www.youtube.com/watch?v=7TtI...
🎤 Call for Speakers: Nextflow Summit Boston 2026! 🌏 #NextflowSummit, presented by @seqera.io, returns this spring (Apr 30 - May 1), bringing together researchers, developers, and industry leaders to shape the future of biotech R&D.
Since recording I've been playing with it for some nf-core stuff and have found it super useful.
Using #Terraform to configure properties and setup within Seqera platform is super cool, allows proper automation and dev tooling around "the stuff that encapsulates Nextflow runs".
This is one of those episodes where I went in knowing genuinely very little about the topic, and learnt a lot!
I'd heard of #terraform a lot over the years and had a rough idea of what it was for, but didn't really know how it worked. And I had no idea how similar to @nextflow.io it is!
🎉 Nextflow Training Week by @seqera.io kicks off today! Join 1000+ others diving into workflow management with our beginner-friendly courses, including Hello Nextflow, RNA-Seq, and Imaging.
🚀 Register now: hubs.la/Q042fkSy0
🎉 Registration for the nf-core hackathon is now open! Join us online or in-person on March 11-13 for collaborative coding, pipeline development, and community building 💻
Bring your own project or choose from our community issues.🔧 Every project has a lead to guide you! nf-co.re/events/hacka...
Let's goooo! Registration numbers for 2025 were insane, let's see if we can do even better in 2026 😉
For podcast episodes, I write a summary blog post that goes on the seqera.io/podcasts episode page 🎙️
So if audio isn't your thing, you can get an overview by reading that. Or point your favourite LLM at the web page (which also has the full transcript) and ask about the episode interactively ✨
It's doubly powerful for YouTube, as that has an automatic translation mode for closed captions / subtitles, so you can follow along in your native tongue.. 🗺️ 🌐
Oh, and training.nextflow.io/latest/ is also now fully translated into 10 languages 🎉 (tell us if you'd like more!)
Current status: deep into video editing mode 👨🏻💻 🎧
Did you know that all @nextflow.io #training videos (and podcasts!) have their subtitles manually curated? They're really high quality - even for technical terms.
Great if English is not your first language, or if you can't understand my accent! 😆
The wet-lab results from @adaptyv.bio's Nipah Binder Competition are in! 🧪 While our candidate didn’t bind, the results highlight the importance of experimental validation in protein binder design.
📚 Read the blog: hubs.la/Q041NGGt0
💻 Attend the webinar: hubs.la/Q041NH8C0
This is shaping up to a very interesting webinar - quite excited to hear this one myself!
Sign up for free and join us next week!
Or follow the training async whenever you like. Join the revolution 🎉 ✨
The courses now all teach the new Nextflow "strict syntax" and modern features like Workflow Outputs. Even if you've done the training before it's perfect for a refresher and to put these new language features in context 🗺️
We've been working really hard on a refresh of the super popular #Nextflow training materials.
@geraldinevda.bsky.social has rewritten much of #Hello #Nextflow and #Nextflow #Run and I'm in the process of recording new videos 📹📼🎞️
This was a lot of fun! 🎙️The way that @seqera.io #Fusion filesystem (and the new #Fusion #Snapshots) works has always seemed like magic to me 🪄 so I got Lorenzo to break it down and explain.
Ok it's still magic, but now I have *some* idea what eBPF and Kernel operations and process freezing means 😂🧊
Ah I feel you. In the Nextflow docs we recommend using SDKMAN! Generally I find that once you get that running stuff works.. sdkman.io
Cool! This is the VSCode extension? What were the difficulties / solution?
🎉 Save the date! nf-core Hackathon — March 11-13, 2026!
Hybrid format: in-person hubs worldwide + online participation
👉 nf-co.re/events/2026/...
🧵👇
Next month, @ewels.bsky.social (Product Manager for OSS at @seqera.io)will be joining the Bioinformatics CRO webinar series to discuss #Nextflow, @nf-co.re, and exciting new features for reproducible bioinformatics at scale. 👇
hubs.la/Q040__J00
Stay tuned for this hitting the @nextflow.io training ("Hello Nextflow" and "Nextflow Run" courses) imminently. We might spin a Claude skill up for writing quizzes too, I could share if of interest..
Yup, that's what I've been doing in training material elsewhere - the syntax is pretty simple so if you give it the link to the mkdocs-quiz docs and tell it to write quizzes for your material it does a pretty good job out of the box.
It works with local files, git repos, and even web URLs. And you don't need MkDocs if you only want the terminal experience! Pretty cool.
github.com/ewels/mkdocs-quiz
The CLI is handy if you're already in a terminal - run `quiz`, pick from available quizzes in your repo, and test your knowledge without switching to a browser.
It uses rich for beautiful markdown rendering with syntax highlighting 🌈, plus has a `history` command to track your scores.
