Keunwoo Ryu

Really enjoyed writing this spotlight highlighting recent works from @keunwooryu.bsky.social at al in the Thompson lab along with @lyssiotislab.bsky.social and Yatrik Shah! Mitochondria heterogeneity FTW!
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Link below to the spotlight and the original @nature.com articles in the reference👇

Congrats to @keunwooryu.bsky.social‬, a research associate at MSK, for receiving the 2025 Tri-Institutional Breakout Prize for Junior Investigators! Dr. Ryu was selected for his work revealing how mitochondria compartmentalize #proline synthesis via metabolic enzyme filaments under nutrient stress.

Just out in @science.org: Together with the lab of @johanneszuber.bsky.social, we used sequential in-vitro/in-vivo screens to decipher metabolic adaptations in tumors. We find that acidosis is a dominant factor that shapes energy metabolism and stress resilience. www.science.org/doi/10.1126/...

📖Read the full story: imp.ac.at/news/article...

@johanneszuber.bsky.social, @wilhelmpalm.bsky.social, @dkfz.bsky.social, @viennabiocenter.bsky.social

Thanks Juanma for your support! Excited to finally share my paper with everyone!

A transmitochondrial sodium gradient controls membrane potential in mammalian mitochondria Eukaryotic cell function and survival rely on the use of a mitochondrial H+ electrochemical gradient (Δp), which is composed of an inner mitochondrial…

As my postdoctoral mentor likes to say: "cells didn't read your textbook!". A perfect example: www.sciencedirect.com/science/arti... . Just wow!!