The February issue of #G3journal features research from @matthewberg22.bsky.social and colleagues showing how mistranslating tRNAs in #yeast can alter the abundance and phosphorylation of proteins involved in proteostasis, cell cycle, and translation. buff.ly/LKhFZFy
Check out our new work now published in G3! We use proteomics and phosphoproteomics to study how cells cope with tRNA variants that mis-insert amino acids.
One week left!
Nominations for CSMB Fellows and 2026 CSMB Awards close January 15.
Do you know someone whose research, leadership, or service deserves recognition?
Nominating is simple! Don't miss the chance to highlight outstanding colleagues.
Learn more and submit nominations: csmb-scbm.ca
🙏🏽 @matthewberg22.bsky.social & @csmb-scbm.bsky.social for capturing my thoughts on mentorship so thoughtfully. Grateful to have @biochemcellbio.bsky.social publish them and to be part of an important conversation on supporting the next generation of scientists.
blog.cdnsciencepub.com/trushar-patel/
We invite you to read the article “The unsung guardians of Canadian dominion, innovation, and prosperity” by Thomas Pulnilkunnil, Ecaterina Cozma and Walid Houry, published in the Hill Times last week: www.hilltimes.com/story/2025/0...
Mistranslating tRNA variants impact the proteome and phosphoproteome of Saccharomyces cerevisiae https://www.biorxiv.org/content/10.1101/2025.09.15.676438v1
Announcing the yEvo Mutation Browser, a Shiny app for visualizing and exploring sequencing data from experimental evolution and genetic screens. This is the latest from our @yevolab.bsky.social high school teaching & research project and led by my grad student Leah. www.biorxiv.org/content/10.1...
Interested in using functional data to understand clinical variants? Been hunting for a good review of the topic? We just wrote one! rdcu.be/exaEU
We're hiring! Job Posting: Part-Time Administrative Assistant (Bilingual English/French) Canadian Society for Molecular Biosciences (CSMB) csmb-scbm.ca/job-posting-...
🤔 Are you unsure what jobs you can get with your molecular biosciences degree, other than research? Then join the @csmb-scbm.bsky.social next Thursday, June 19, for our next webinar where we'll hear from three scientists with jobs in scientific writing!
Sign up here: zoom.us/meeting/regi...
Congratulations to our 2025 CSMB Fellows!
A great start to day 1 of the @csmb-scbm.bsky.social 2025 conference in Ottawa!
If you're around, make sure to come out to my talk on Wednesday morning in the "Protein Folding and Aggregation" session. I'll be talking about the cool stuff I've been doing in the @jvillen.bsky.social lab.
The inaugural CSMB Fellows were also recognized tonight. Congratulations to Dr. Imogen Coe, Dr. Jan Rainey and Dr. John Orlowski! @csmb-scbm.bsky.social
R2HaPpY: Rapid-robust phosphotyrosine peptide enrichment using HaloTag-Src SH2 pY superbinder https://www.biorxiv.org/content/10.1101/2025.05.14.653984v1
If you study phospho-signaling, make sure you check out this work!
I'm thankful to Alexis and Judit for letting me be a part of this project and I'm really excited for others to try this reagent and method. Congrats to all the authors!
Alexis does a lot of amazing work benchmarking the reagent/method. She demonstrates how powerful it is by applying it to EGF-stimulated cells, uncovering over 1600 unique pY sites including many low abundance and previously uncharacterized sites with as little as 1 mg of peptide input per sample!
We estimate our approach for enriching pY-containing peptides is ~ 10x cheaper than using pY antibody magnetic beads and our magnetic enrichment reagent can easily be prepared by any lab that can grow E. coli!
The latest work from the @jvillen.bsky.social lab @uwgenome.bsky.social is out now on bioRxiv!
Do you want to study phosphotyrosine signaling easily, cheaply and reproducibly? Then check out Alexis' work developing a method for systems-level pY signaling studies!
www.biorxiv.org/content/10.1...
I'm really excited for this month's @csmb-scbm.bsky.social seminar! It should be a great set of talks 🧪
Our next @csmb-scbm.bsky.social seminar is coming up on Tuesday May 13th at 9am ET! Make sure you tune in to hear about exciting Canadian research 🍁 This month, we'll hear about retro-evolution of the ribosome and Akt signalling in breast cancer.
Sign up here: tinyurl.com/5n9xtrmw
Reminders: March 31 is the deadline for early-bird meeting registration and CSMB Fellows program applications. April 2 is the deadline for the CSMB Mentorship initiative applications. Details on our website:
Don't miss out on these seminars! They've been awesome so far and these talks tomorrow sound like they will be equally as great!
📢REMINDER: Don't miss out on our @csmb-scbm.bsky.social seminar next week. Come here about the exciting science happening in Canada!
Sign up here: tinyurl.com/5n9xtrmw
The CSMB is excited to launch of the CSMB Fellows program. The deadline for applications is set for March 31, 2025. Learn more about this new initiative on our website
Nominations now accepted for the 2025 CSMB Awards, updated deadline for submissions on Jan 15, 2025:
-CSP Senior Investigator Award
-Jeanne Manery Fisher Memorial Lecture
-CSMB New Investigator Award
-Frances Sharom Science Communication Award
Details: https://buff.ly/419Ymlt
