22.01.2026 08:10
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Embarrassing
NEW: @origgio.bsky.social and I went back and fact checked more of the misleading and false narratives in Plague of Corruption, the anti-vax documentary narrated by Liam Neeson.
For more of this kind of journalism, support @accountabilityji.bsky.social
www.importantcontext.news/p/fact-check...
Very much enjoyed BSI Annual Congress in Liverpool. Excellent programme, outstanding speakers and great chance to catch up with a lot of familiar faces #BSI25
What a game. I was an undergrad the last time we were at the WC, been a long time coming!
Diagram showing how sand fly saliva changes fibroblast state to promote arbovirus infection.
New paper out in iScience @cellpress.bsky.social
We show that #sand_fly biting reprograms skin fibroblasts, making them more permissive to virus infection
=> #fibroblasts aren’t bystanders, they help define severity/clinical outcome to infection AND #vector biting is key
👉 doi.org/10.1016/j.is...
When was the last time you heard a politician in the media asked anything like-
-How will you make sure asylum seekers can reach the UK safely & refugees are protected?
-How will you make sure people coming to this country to work or study are treated equally & with respect?
I cannot remember.
Very pleased to share the latest data from the lab, out today in @naturecomms.nature.com ! We show 🧠 infiltrating CD4 Tcells drive inflammatory #microglia proliferation during fungal meningitis, contributing towards early clinical symptoms
www.nature.com/articles/s41...
“A study, published on Wednesday in the New England Journal of Medicine, showed that last season’s 2024–2025 mRNA COVID vaccines reduced people’s risk of emergency department visits by 29%, their risk of hospitalizations by 39% & their risk of death by 64%”
Benefits were seen even if 0 risk factors
Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
I only ever heard second-hand from my German relatives what the 1930s were like but it sounded like this. You see the story, it feels wrong, but everyone else around you is just carrying on, shopping, working, going to the cinema. So you do the same. Keep your head down, maybe this is fine? Normal?
We have developed hyper-migratory CAR T cells that alleviate ovarian cancer metastatic burden and improve prognosis.
We transduce synthetic modular "velocity" receptors that promote fast and deep infiltration of CAR T cells into mets in the liver.
More here: www.biorxiv.org/content/10.1...
Keith was one of my absolute heroes. Shaped my musical tastes substantially as a student in 90s Edinburgh, through visiting his pre-Optimo club Pure. Gone way too soon
Latest preprint from us
To say that "the data show these vaccines fail" in regards to the mRNA plaform is unforgivable.
For those of you that don't remember - this is the data from a SINGLE dose. In December 2020. So good I cried in grateful tears.
JUST IN: HHS shuts down BARDA mRNA vaccine program
Scrapping the fastest platform we have is a reckless move rooted in a fundamental misunderstanding of vaccinology. No respiratory vaccine blocks all infections. mRNA vaccines have saved millions of lives.
www.hhs.gov/press-room/h...
We knew this deeply misguided man was bad news, but now his actions threaten us all. RNA-based vaccines are safe, effective at preventing disease, and can be rapidly manufactured at scale. Just as the threat of infectious disease increases, we remove our best defence. www.bbc.co.uk/news/article...
Former Mossad, Shin Bet and IDF leaders join most of the world in demanding an immediate end to the Gaza war, saying it’s now an unjust, immoral and futile war of destruction guided by 'messianic and extremist goals' and threatening ‘the loss of Israel's security and freedom.’ It must end now.
Please sign this Parliamentary petition calling for comprehensive trade sanctions on Israel - the limited sanctions on specific members of the Israeli Government by the UK do not go far enough: petition.parliament.uk/petitions/72...
It’s brilliant. A strange mix of in depth cricket stats and analysis and random discussion of anything and everything that occurs to them
1/ 🚨 Hot off the press in Nature Immunology: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. www.nature.com/articles/s41... 🧵(1/11)
A more personal substack post today about the first refugee I hosted through @refugeesathome.bsky.social .
It's not something I talk about much but I felt I needed to write something in response to the increasingly hostile environment for refugees.
christinapagel.substack.com/p/the-path-t...
Pres, Gagliardi, of the 🇺🇸 Federation of Musicians:
“We will not remain silent as 2 of our members Bruce Springsteen & Taylor Swift r singled out & personally attacked by the POTUS. S&S r not just brilliant musicians, they r role models & inspirations 2 millions of ppl in the US & across the🌍”
👏🏼👏🏼👏🏼👏🏼👏🏼
My daughter receives world-class care from the paediatric T1D team at @LeedsHospitals
It's not a service to be cut. It's the standard of care that the entire #NHS should be aiming for
This is not the way forward @wesstreeting.bsky.social
@rachelclarke.bsky.social
www.bbc.co.uk/news/article...
"Masked security forces captured an opposition leader in the coastal province of New Jersey as regime officials continue their months-long crack-down against pro-democracy elements in the embattled United States. The arrest comes as the regime issued calls for summary detentions without trial."
Increase in productivity since 1979: 86%
Increase in hourly pay since 1979: 31%
Just so happens that ~25% of workers were unionized in 1979. Today? 10%.
As unions declined, the super-rich have taken a larger share of wealth generated by labor. We must build back union power.
Our review on Protein Synthesis and Metabolism in T cells is out @annualreviews.bsky.social @cantrell-lab.bsky.social
Protein Synthesis and Metabolism in T Cells #proteomics #immunometabolism #Tcells
www.annualreviews.org/content/jour...
Congrats @lindavsinclair.bsky.social on your (and Doreen’s) Annual Review. A must read. www.annualreviews.org/content/jour...
