Maria Fleseriu, MD

Sporadic #prolactinomas are the most common functioning #pituitary #adenomas, with a female predominance during reproductive years. In men, these adenomas are usually larger and more aggressive www.thelancet.com/journals/lan...
#hyperprolactinaemia #prolactin

#MedSky #EndoSky #OncSky

Osilodrostat Achieves Rapid, Sustained Response in Cushing Osilodrostat provides rapid and sustained control of urinary free cortisol levels in patients with Cushing syndrome and has manageable adverse events, a recent analysis shows.

Data analysis from three clinical trials found that #osilodrostat rapidly lowered urinary free #cortisol levels in patients with #CushingDisease within 4-12 weeks.https://www.medscape.com/viewarticle/osilodrostat-achieves-rapid-sustained-response-cushing-2025a1000suu?form=fpf

Read our December Issue, featuring familial hypercholesterolaemia, chronic kidney disease, type 2 diabetes, cyclic Cushing’s syndrome, primary aldosteronism, type 1 diabetes, menopause, obesity, iodine deficiency, & much more tinyurl.com/mwfu4c6m

#MedSky #EndoSky #RenalSky #CardioSky

Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study Even in specialised centres, cCS diagnosis and management remain challenging with high rates of spontaneous adrenal insufficiency, inappropriate surgeries, and poor outcomes. Ectopic cCS showed the mo...

Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study thelancet.com/journals/lan...
cyclic #Cushing's syndrome (#cCS)

#MedSky #EndoSky

#Hyperprolactinaemia can result from dopamine antagonist drug effects and reduced prolactin clearance with liver or kidney disease with loss of feedback regulation thelancet.com/journals/lan...
#prolactinoma #pituitary #adenoma

#MedSky #EndoSky

#Prolactinomas are the most common pathological cause of #hyperprolactinaemia and represent approximately half of #pituitary #adenomas thelancet.com/journals/lan...
#pituitary

#MedSky #EndoSky

Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study Even in specialised centres, cCS diagnosis and management remain challenging with high rates of spontaneous adrenal insufficiency, inappropriate surgeries, and poor outcomes. Ectopic cCS showed the mo...

New—Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study thelancet.com/journals/lan...
cyclic #Cushing's syndrome #cCS

#MedSky #EndoSky

Cycle characterisation and clinical complications in patients with cyclic Cushing's syndrome: insights from an international retrospective cohort study Even in specialised centres, cCS diagnosis and management remain challenging with high rates of spontaneous adrenal insufficiency, inappropriate surgeries, and poor outcomes. Ectopic cCS showed the mo...

Even in specialised centres, cyclic #Cushing's syndrome (cCS) diagnosis and management remain challenging with high rates of spontaneous #adrenal #insufficiency, inappropriate surgeries, and poor outcomes www.thelancet.com/journals/lan...
cyclic #Cushing's syndrome #cCS

#MedSky #EndoSky

Prolactin-secreting adenomas: pathogenesis, diagnosis, and management Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as prolactin-secreting pituitary adenomas and other pituitary stalk-compressing masses...

Prolactinomas are the most common pathological cause of hyperprolactinaemia and represent approximately half of pituitary adenomas thelancet.com/journals/lan...
#prolactinomas #hyperprolactinaemia #pituitary

#MedSky #EndoSky

A proposed updated algorithm for medical treatment in patients with acromegaly that is inadequately controlled after pituitary surgery.

From our November issue: a Consensus Statement on acromegaly therapeutic outcomes from Andrea Giustina and colleagues go.nature.com/3KJIQa8 #EndoSky #MedSky

Great review, Niki ! These tumors are most challenging indeed !

#Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as prolactin-secreting #pituitary #adenomas and other pituitary stalk-compressing masses www.thelancet.com/journals/lan...
#prolactinomas

Our October Issue is now online, featuring prediabetes remission, obesity, type 1 diabetes, biased GLP-1 receptor agonists, type 2 diabetes, prolactin-secreting adenomas, malnutrition-related diabetes, food system, NCDs & much more www.thelancet.com/journals/lan...

#MedSky #EndoSky #OncSky

#ENDO2026 Welcomes Your Ideas | Our annual meeting will take place in Chicago, IL, June 13–16, and I’m inviting YOU to shape the program💡Submit your symposium proposal or session suggestion by Tuesday, September 2: bit.ly/4flCMjl
#endocrinology @TheEndoSociety

Prolactin-secreting adenomas: pathogenesis, diagnosis, and management Hyperprolactinaemia can result from physiological causes, pharmacological agents, or pathological conditions such as prolactin-secreting pituitary adenomas and other pituitary stalk-compressing masses...

Prolactin-secreting adenomas: pathogenesis, diagnosis, and management - The Lancet Diabetes & Endocrinology
Personalized Share Link free download
authors.elsevier.com/a/1lfru_oLbg...

Figure outlining a holistic person-centred approach to management of acromegaly-related diabetes mellitus.

In this Review, Daniela Esposito et al discuss the pathophysiology, clinical challenges and management of #diabetes mellitus in patients with #acromegaly (£) bit.ly/3HkGAVp #EndoSky #MedSky

Consensus on acromegaly therapeutic outcomes: an update Nature Reviews Endocrinology, Published online: 13 August 2025; doi:10.1038/s41574-025-01148-2In this Consensus Statement, an international group of experts provide updated recommendations on the treatment of acromegaly, including discussion of treatment outcomes.

New content online: Consensus on acromegaly therapeutic outcomes: an update

#ENDO2025 - enjoyed scientific sessions reconnecting w/ friends and colleagues. A perfect mix of science & fun! @endocrinesociety.bsky.social @lmfendo.bsky.social @garydouglashammer.bsky.social @jeromebertherat.bsky.social @cronchi.bsky.social @mariafleseriu.bsky.social @bferrazdsouza.bsky.social

Join us for a @endocrinesociety.bsky.social and Pituitary Society session with Dr @mariafleseriu.bsky.social and Dr Ken Ho.

I’ll present our new sc multiomics results identifying gene regulatory circuits differentiating NFPA cells and control gonadotropes.

@endocrinenews.bsky.social

Great & friendly international exchanges on pituitary diseases at the 19th International Pituitary Congress in San Francisco.
👏👏 @mariafleseriu.bsky.social
👏Kristina Isand for presenting the European perspective on #Cushing & venous thrombosis 👍

I’m here! #ENDO2025
Board meeting tomorrow and #ECF2025 Friday. One of my favorite events is the early career forum by the @endocrinesociety.bsky.social
Can’t wait to meet the trainees and often first timers to ENDO.

Endocrine Society (@endocrinesociety.bsky.social) We unite, lead, and grow the global endocrine community to accelerate scientific breakthroughs and improve health worldwide. endocrine.org

SF bound ✈️!

Looking forward to meeting colleagues and collaborators and learning about all the science at #ENDO2025 and the Pituitary Society meetings.

@endocrinesociety.bsky.social

Happy to share our recent #consensus #guideline on how to multidisciplinary manage #pituitary #incidentalomas; good news on data to recommend less frequent #imaging for many microadenomas , but also smaller macroadenomas. @pituitarysociety.bsky.social @ohsubrain.bsky.social @ohsunews.bsky.social

Pituitary incidentaloma: a Pituitary Society international consensus guideline statement Nature Reviews Endocrinology, Published online: 24 June 2025; doi:10.1038/s41574-025-01134-8This international Consensus Statement provides guidelines on the management of pituitary incidentalomas.

New content online: Pituitary incidentaloma: a Pituitary Society international consensus guideline statement

So good seeing everyone in our #Cushing family. We are leaving with more work to do, energized by collaborative studies. And let’s not forget Munich charm who is so close to Sibiu. Can’t wait for next one!

So good seeing everyone in our #Cushing family. We are leaving with more work to do, energized by collaborative studies. And let’s not forget Munich charm who is so close to Sibiu. Can’t wait for next one!

Polycystic ovary syndrome perspectives from patients and health professionals on clinical features, current name, and renaming: a longitudinal international online survey Widespread international engagement in 2015 showed major knowledge gaps on broad PCOS features, with follow-up in 2023 showing significant improvement after two international guidelines, widespread di...

New @eclinicalmed.bsky.social:
Polycystic ovary syndrome perspectives from patients and health professionals on clinical features, current name, and renaming: a longitudinal international online survey www.thelancet.com/journals/ecl...
#PCOS
#OpenAccess
#MedSky #EndoSky #WomensHealthSky

Guess we have to be there !!! Congrats, Niki !

Surgery for the treatment of arterial hypertension in patients with unilateral adrenal incidentalomas and mild autonomous cortisol secretion (CHIRACIC): a multicentre, open-label, superiority randomis... MACS associated with unilateral adrenal incidentalomas is responsible for secondary hypertension that can be safely improved by minimally-invasive adrenalectomy.

Mild autonomous cortisol secretion (MACS) associated with #unilateral #adrenal #incidentalomas is responsible for secondary #hypertension that can be safely improved by minimally-invasive #adrenalectomy www.thelancet.com/journals/lan...

#MedSky #EndoSky #OncSky #CardioSky

The first-ever joint ESPE-ESE congress will begin this Saturday. I look forward to meeting our warm and vibrant community in Copenhagen. 👇👇👇

PS: For those unable to attend, there is still time to register online to participate in this great event !