Mischa Lundberg

Very happy that this part of my postdoc work is now out as a preprint!! Our findings reveal a new mechanism by which retroviral pandemics may have shaped primate brain evolution 🧬🐒🧠 This was a true team effort! w/ @ofeliakarlsson.bsky.social @raquelgarza.bsky.social @jakobssonlab.bsky.social #TEsky

Congratulations to @joerimeijsen.bsky.social & co-authors on this fantastic piece of work ✨

Stefana Aicoboaie, Cynthia Bulik, @helenadavies.bsky.social @MischaLundberg @mischalundberg.bsky.social @cedar-research.bsky.social Joelle Pasman, Nadia Micali, Kejia Hu, Dang Wei & many more

6/6

Another successful year with our workshop at #UniStemDay2025. We explained to high school students how we study human brain evolution using human and monkey brain organoids and looking at gene expression 🧠🐒🔬🧬 w/ @vivienhorvath.bsky.social @ofeliakarlsson.bsky.social @lundstem.bsky.social

Profiling and targeting young L1s is no easy matter 🧐 check out our new preprint to see how we delve into transcriptional and epigenomic profiling of L1s, and investigate their involvement in pluripotency and early brain development 🧠

LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development Long interspersed nuclear element 1 (L1) retrotransposons represent a vast source of divergent genetic information. However, mechanistic analysis of whether and how L1s contribute to human development...

New preprint from our lab. Led by the outstanding @anitaada.bsky.social and @raquelgarza.bsky.social. Funded by @asapresearch.bsky.social and @vetenskapsradet.bsky.social.

LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development

www.biorxiv.org/content/10.1...

Shared Genetic Architecture Between Eating Disorders, Mental Health Conditions, and Cardiometabolic Diseases: A Comprehensive Population-Wide Study Across Two Countries Eating disorders arise from a complex interaction of genetic and environmental influences. Here we provide comprehensive population-level estimates of the heritability of eating disorders and their ge...

Check out our latest preprint about the shared #genetics of #eatingdisorders and many other outcomes! We used the massive national registers of 🇩🇰 and 🇸🇪 and observed new genetic overlap between EDs and Autism and replicated previous OCD findings. www.medrxiv.org/content/10.1...

Multiscale analysis and functional validation of the cellular and genetic determinants of skeletal disease

Thrilled to share our latest Research (including a part of my PhD) uncovering key cells and genes driving skeletal disease! 🚀

This work wouldn’t be possible without our incredible team, mentors, collaborators, and funders. 💡✨

Check it out: biorxiv.org/cgi/content/...

Hi @chenyangsu.bsky.social , could you please add me too? Thanks!

Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease https://www.biorxiv.org/content/10.1101/2023.10.20.563233v1 SVA retrotransposons remain active in humans and contribute to individual genetic variation. Polymor

Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease https://www.biorxiv.org/content/10.1101/2023.10.20.563233v1