More about the GEMINI consortium project: www.imp.ac.at/news/article/fwf-grant-genetic-information-across-generations
@fwf-at.bsky.social @istaresearch.bsky.social @viennabiocenter.bsky.social @oeaw.bsky.social
A consortium of group leaders from IMP, IMBA (Vienna BioCenter) and ISTA has been awarded an FWF Emerging Fields grant to study how germ cells safeguard and pass on genetic information across generations.
The new Vienna BioCenter Interdisciplinary Postdoctoral Program (VIPยณ) is here! We have 8 fully-funded positions for scientists with a PhD in biology, chemistry, physics, bioinformatics etc.
The call is open!
More information: training.vbc.ac.at/post-docs/vi...
#VBCPostDoc
How does one genome create so much complexity?
๐ฝ๏ธ 2025 Birnstiel Award laureate Jimmy Ly discovered hidden protein variants in the โdark proteomeโ that shape cell function and disease: https://youtu.be/wY1HbfY3fTE
๐ Congratulations to our Ezra Levy, postdoc in Andrea Pauliโs lab at the IMP, who has been awarded a prestigious Marie Skลodowska-Curie Postdoctoral Fellowship.
More about his project: https://www.imp.ac.at/news/article/ezra-levy-awarded-marie-sklodowska-curie-postdoctoral-fellowship
Register online for SY-Stem: www.sy-stem.org.
SY-Stem โ a symposium focusing on the next generation of stem cell researchers โ is organized by IMBA and the IMP at the Vienna BioCenter.
Final registration reminder for SY-Stem 2026. The deadline is on Monday, February 16.
@viennabiocenter.bsky.social
Viruses shut down antiviral defences to evade detectionโbut this can backfire. Researchers uncovered how human immune cells sense viral sabotage and trigger inflammation. UC Berkeley study with contributions from IMPโs Moritz Gaidt: https://www.science.org/doi/10.1126/science.adw4937
Read more: www.imp.ac.at/news/article...
@haselbachlab.bsky.social, @johanneszuber.bsky.social, @viennabiocenter.bsky.social
To regulate gene activity, proteasomes - waste disposal machines of cells - must enter the nucleus. IMP Researchers now show how the adaptor protein AKIRIN2 helps ferry this massive complex through the nuclear pore: https://www.nature.com/articles/s41467-026-69162-0
Sven Klumpe, joint Group Leader at the IMP and IMBA has received a grant by the Chan Zuckerberg Initiativeโs Biohub to support fibsem-os, an open-source software platform for focused ion beamโscanning electron microscopy.
Read more ๐ https://imba.science/4tiwEP9
@maxperutzlabs.ac.at, @viennabiocenter.bsky.social
https://www.imp.ac.at/achievements/research-milestones/alipasha-vaziri-neuronalactivity
๐ฌ Our Research Milestones essays are back!
This feature highlights Alipasha Vaziri, former Group Leader at the IMP and Max Perutz Labs.
At the IMP, he developed imaging technologies that enabled large-scale recording of neuronal activity at single-cell resolution:
Paper alert! ๐ข How do cells fight viruses without harming themselves? ๐งฌ In @natcomms.nature.com, the @versteegga.bsky.social lab uncover a previously unknown safeguard that keeps DNA-mutating antiviral enzymes in check, protecting the genome while preserving antiviral defense โก๏ธ tinyurl.com/4xbxz9e8
Apply to the technical assistant position at IMBA, IMP, and GMI: https://www.oeaw.ac.at/imba/career-education/open-positions/pos2601-technical-assistant
#research #jobs #europe #biology
We are hiring! Join our Sterile Processing Unit as a technical assistant and provide scientists at the IMP, IMBA, and GMI with sterile laboratory glass and plastic goods.
https://rupress.org/jem/article/223/3/e20250594/281445/In-vivo-CRISPR-Cas9-screens-identify-new
Meinrad Busslinger at the IMP have now developed a new CRISPR screening strategy that allows gene function to be studied directly in immune cells inside living mice.
Using this approach, the team identified dozens of previously unknown genes that control plasma cell formation. Beyond new insights
Plasma cells are the immune systemโs antibody factories, producing the molecules that protect us after infection or vaccination. They originate from B cell. Yet how B cells make the switch to become plasma cellsโand which genes control this transitionโisnโt known.
Researchers from the lab of
Plasma cells are the immune systemโs antibody factories, and they originate from B-cells.
Researchers from our Busslinger lab developed a new CRISPR screening method to find the genes that control this transition inside living mice:
More: www.imp.ac.at/news/article...
@viennabiocenter.bsky.social, @haselbachlab.bsky.social, @lgrundmann.bsky.social
New work from our Haselbach lab with collaborators captures ribosomes ๐ฎ๐ช๐ฅ-๐ฃ๐ถ๐ช๐ญ๐ฅ and reveals a flexible, modular strategy behind their assembly, rather than a strict assembly line.
Published in _Nucleic Acids Research _๐ https://doi.org/10.1093/nar/gkag036
Check out our new paper in @natcomms.nature.com .com where we used #cryoEM together with biochemical and mutational analyses investigated the cotranslational protein folding by Ssb in yeast.
Publication: doi.org/10.1038/s41467-025-67685-6
Check below for the cryoEM centric feed. ๐
BLOC-1 and BORC help move and position lysosomes inside cells. New work from the Haselbach and Clausen labs shows they are not uniform complexes, but families of related protein assemblies. Published in PNAS: https://www.pnas.org/doi/10.1073/pnas.2515691123
