ETVAX is the first vaccine that offers significant protection against pathogenic E. coli in children
ETVAX is the first vaccine that offers significant protection against pathogenic E. coli in children
Lovely round up of science books for children by the editors at @science.org. As my kids get older, I'm going to have to confront the fact that I'm really getting the books for myself not for them.
www.science.org/doi/10.1126/...
It makes me happy to see papers transferred to sister or society journals. We get a lot of good papers that we can't keep for various reasons, not clinical enough, too early etc. I put a lot of effort into finding them a home -- today was a good day, 7 transfers of great papers to great journals.
Pipeline of new drugs to fight superbugs is βworryingly thinβ, experts warn
A bumper crop of mpox content - 1 comment and 4 research articles π
From emergency to integration: research as the bridge in mpox control
www.thelancet.com/journals/lan...
New funding for infectious disease clinical trials! π£β―
Weβre funding randomised controlled trials to optimise existing vaccines and therapeutics for infectious diseases.
Delivered in partnership with @nihr.bsky.social and FCDO Research.
Learn more about eligibility and how to apply ‡οΈ
Abstract submissions for #GAMRIC2026 are now open!
We encourage submissions in: preclinical/clinical development, new antibacterial/antifungal classes, AMR diagnostics & epidemiology, vaccines, and many more!
Travel grants are available.
Learn more: https://ow.ly/i0Me50Yq7Fl
#IDSky #clinmicro
"Russian flu," the pandemic that hit in 1977, bears an evolutionary signature of having emerged from a lab, perhaps as part of a failed vaccine effort. Covid, mpox, Ebola, and other influenza pandemics don't. Here's my story on a new way to trace the origins of pandemics. Gift link: nyti.ms/46N0W33
βNo one quite like herβ: meet the female colleagues who inspire these award-winning women in science
To mark International Womenβs Day, Nature asked winners of its awards programmes to nominate a colleague who brings out the best in them.
www.nature.com/articles/d41...
That looks amazing! I'm away this week, missed it.
There's epi/modelling work, eg this one looking at England. Overall, waning happens, however, it's very slow compared to many other viral vaccines. It's not impossible to get infected if you were vaccinated and on a population level adds up, individual risk low.
www.thelancet.com/journals/lan...
The updated International Committee of Medical Journal Editors (ICMJE) recommendations suggest what journals can do to ensure appropriate use of AI, but real compliance starts in the institutions where researchers learn their habits. buff.ly/DVxxIJZ
Anyway, thanks for the paper. Very interesting!
Less screening leads to longer TATs. Also not sure whether one can directly compare initial desk decision with peer review decisions. For selective journals can former can be done quite reliably. Second is not only about accept/reject, more so about improving article.
I'm obviously biased
, but as an editor at a selective journal, I'm not sure whether tighter screening and desk rejections really turns authors off submitting. If they have a high-quality paper, they want it published with other high-quality peer papers. What turns them off is very long TATs.
β‘οΈ It's on! Paid internship for aspiring science journalists at Nature's London office. Up to three days a week working from home. All the details are here: springernature.wd3.myworkdayjobs.com/en-US/Spring...
Also, I wouldn't rate longer reports and longer replies as a positive outcome...
Loved this week's episode; never a good sign if your surgeon says yikes... Also wondering whether John Tothill was in one of our malaria challenge papers.
Reading peer review reports: Reviewer 2 saying I LOVE THIS, BRAVO in all caps. My heart β€οΈππ₯²
What annoys me is if protocols are heavily redacted because of commercial or competition concerns. Ok, don't want to publish everything in appendix but at least need transparency for editorial assessment and peer review.
Rant over π
For clinical trials, we check protocols before publication. Can be complex though, eg if there's protocol changes, trials are registered in more than one registry, or protocols are not in English (we ask for translation or editorial colleague who knows language check, love diverse Lancet team).
Exactly. Issued when there are concerns warranting further investigation (usually by institution). What happens afterwards depends on findings. Correction, retraction, no action. For last, I would like to see note to say investigated and resolved. Doesn't always happen.
Exactly. That and how much strain regular stuff such as commuting or being 'on' in an office for a traditional workday can put on disabled people. It's a shame that much of the progress in flexible working is being rolled back.
A potential late sequelae of measles after normal recovery.
Occurs in ~ 2/10,000. Fatal.
www.nejm.org/doi/full/10.... @nejm.org today
π§ͺ #ResearchEthics
Appalling Guinea Bissau #hepB #vaccine trial
βan international ethics fiasco[β¦]
ββ¦CDC appointees allied with Kennedy circumvented critical scientific and ethical safeguardsβ¦β
Kudos to investigative journalist @katherineeban.bsky.social
www.rollingstone.com/politics/pol...
Panel A shows the cumulative incidence of regimen failure (the primary outcome), which was defined as the earliest occurrence of either virologic failure or permanent discontinuation of the trial treatment. Also shown is the cumulative incidence of virologic failure, treatment-related failure (defined as the earliest occurrence of virologic failure or premature treatment discontinuation due to treatment-related adverse events), and permanent discontinuation (key secondary outcomes). Panel B shows the times to regimen failure and virologic failure in step 2. The week 48 visit was performed within a prespecified window (>42 to 50 weeks after randomization). CI denotes confidence interval.
Cabotegravir plus Rilpivirine for Persons with HIV and Adherence Challenges
Aadia Rana & co for the ACTG A5359 LATITUDE Trial Team
Monthly cabotegravirβrilpivirine were superior to standard ART in reducing failure among PWH who had adherence challenges
www.nejm.org/doi/full/10.... #IDSky #HIVSky
Zing, virus taxonomy wars continue. Language stickler in me welcomes the zeal for order and correctness. Although, if one were very strict that acknowledgement heading should maybe be renamed as conflicts of interest...
Fluffy tabby cat sitting on a bed, head half turned backwards towards camera, looking accusingly
Side eye from a resentful cat. Tonight's atrocities will not be forgiven. Humans left to go to a sea shanty concert each assuming the other one had already fed the cat. Barely escaped starvation.
Everyone can easily find our email, there really is no priority access. If you do decide to send a presub, then at least please include an abstract, full paper if you already have it.