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Lucas Santana Souza

@lucasgenoma

Using mathematical models and individual-based simulations to study the social evolution of microbes, viruses, and endosymbiosis.

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27.01.2025
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Latest posts by Lucas Santana Souza @lucasgenoma

Inducing novel endosymbioses by implanting bacteria in fungi - Gabriel H. Giger (ETH Zürich)
Inducing novel endosymbioses by implanting bacteria in fungi - Gabriel H. Giger (ETH Zürich) YouTube video by Lucas Genoma

youtu.be/SkaPFKazIoc

Endosymbiosis webinar series
Our Guest: Gabriel H. Giger
2025.12.11
Inducing novel endosymbioses by implanting bacteria in fungi

11.12.2025 15:37 👍 1 🔁 2 💬 0 📌 0
Our Guest: Gabriel H. Giger
Title: Inducing novel endosymbioses by implanting bacteria in fungi. 
When: 🌟Thursday, 11th December, at 3 PM (Stockholm time zone). 
Zoom link: https://umu.zoom.us/j/68520264707 
Webinar schedule: https://endosymbiosiswebinar.github.io/
#Endosymbiosis

Our Guest: Gabriel H. Giger Title: Inducing novel endosymbioses by implanting bacteria in fungi. When: 🌟Thursday, 11th December, at 3 PM (Stockholm time zone). Zoom link: https://umu.zoom.us/j/68520264707 Webinar schedule: https://endosymbiosiswebinar.github.io/ #Endosymbiosis

Our Guest: Gabriel H. Giger
Title: Inducing novel endosymbioses by implanting bacteria in fungi.
When: 🌟Thursday, 11th December, at 3 PM (Stockholm time zone).
Zoom link: umu.zoom.us/j/68520264707
Webinar schedule: endosymbiosiswebinar.github.io
#Endosymbiosis

06.12.2025 09:51 👍 4 🔁 2 💬 1 📌 0
Our Guest: Gabriel H. Giger
Title: Inducing novel endosymbioses by implanting bacteria in fungi. 
When: 🌟Thursday, 11th December, at 3 PM (Stockholm time zone). 
Zoom link: https://umu.zoom.us/j/68520264707 
Webinar schedule: https://endosymbiosiswebinar.github.io/
#Endosymbiosis

Our Guest: Gabriel H. Giger Title: Inducing novel endosymbioses by implanting bacteria in fungi. When: 🌟Thursday, 11th December, at 3 PM (Stockholm time zone). Zoom link: https://umu.zoom.us/j/68520264707 Webinar schedule: https://endosymbiosiswebinar.github.io/ #Endosymbiosis

Our Guest: Gabriel H. Giger
Title: Inducing novel endosymbioses by implanting bacteria in fungi.
When: 🌟Thursday, 11th December, at 3 PM (Stockholm time zone).
Zoom link: umu.zoom.us/j/68520264707
Webinar schedule: endosymbiosiswebinar.github.io
#Endosymbiosis

06.12.2025 09:51 👍 4 🔁 2 💬 1 📌 0
The Evolution of Dependence and Cohesion in Incipient Endosymbioses - Gaurav S. Athreya
The Evolution of Dependence and Cohesion in Incipient Endosymbioses - Gaurav S. Athreya YouTube video by Lucas Genoma

youtu.be/YdVzLeTlgBE

Endosymbiosis webinar series
Our Guest: Gaurav S. Athreya
2025.12.04
The Evolution of Dependence and Cohesion in Incipient Endosymbioses

04.12.2025 16:04 👍 3 🔁 2 💬 0 📌 0
Post image

To receive email reminders about the webinar, join the mailing list via our Google Group (a Google account is required):
groups.google.com/g/endosymbio...
If you have trouble joining, please email your name and preferred email address to: endosymbiosiswebinar@gmail.com
umu.zoom.us/j/68775661118

23.11.2025 12:39 👍 1 🔁 2 💬 0 📌 0
Post image

To receive email reminders about the webinar, join the mailing list via our Google Group (a Google account is required):
groups.google.com/g/endosymbio...
If you have trouble joining, please email your name and preferred email address to: endosymbiosiswebinar@gmail.com
umu.zoom.us/j/68775661118

23.11.2025 12:39 👍 1 🔁 2 💬 0 📌 0
Post image

Our Guest: Gaurav S. Athreya.
Title: The Evolution of Dependence and Cohesion in Incipient Endosymbioses.
When: 🌟Thursday, 4th December, at 3 PM (Stockholm time zone).
Zoom link: umu.zoom.us/j/68775661118
Webinar schedule: endosymbiosiswebinar.github.io
#Endosymbiosis

14.11.2025 07:19 👍 1 🔁 1 💬 0 📌 1
Post image

🚨 TLM Seminar Series - TOMORROW|16:00 UK

Eric Libby (@elibbyscience.bsky.social): "Informational constraints on the regulation of early multicellular life cycles"

Join the talk at: www.cam-ac-uk.zoom.us/j/89289153062

Join our mailing list here: lists.cam.ac.uk/sympa/sub...

Please repost!

18.11.2025 17:05 👍 6 🔁 1 💬 0 📌 1
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Our Guest: Gaurav S. Athreya.
Title: The Evolution of Dependence and Cohesion in Incipient Endosymbioses.
When: 🌟Thursday, 4th December, at 3 PM (Stockholm time zone).
Zoom link: umu.zoom.us/j/68775661118
Webinar schedule: endosymbiosiswebinar.github.io
#Endosymbiosis

14.11.2025 07:19 👍 1 🔁 1 💬 0 📌 1
Farming the mitochondrial ancestor as a model of endosymbiotic establishment by natural selection
Farming the mitochondrial ancestor as a model of endosymbiotic establishment by natural selection YouTube video by Lucas Genoma

youtu.be/VnQ5qJryWjE?...
Endosymbiosis Webinar Series.
Our guest: István Zachar
Date: 2025.11.13

Upcoming talks: endosymbiosiswebinar.github.io

14.11.2025 07:16 👍 1 🔁 0 💬 0 📌 0
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Our Guest: István Zachar.
Title: Farming the mitochondrial ancestor as a model of endosymbiotic establishment by natural selection.
When: 🌟TODAY, 13 of November, at 3 PM (Stockholm time zone).
Zoom link: umu.zoom.us/j/61448056807
#Endosymbiosis

13.11.2025 12:01 👍 0 🔁 0 💬 0 📌 0
Post image

Our Guest: István Zachar.
Title: Farming the mitochondrial ancestor as a model of endosymbiotic establishment by natural selection.
When: 🌟NEXT Thursday, 13 of November, at 3 PM CEST (Stockholm time zone).
Zoom link: umu.zoom.us/j/61448056807 #Endosymbiosis

03.11.2025 16:42 👍 5 🔁 2 💬 0 📌 0
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Paradoxical role of new endosymbiotic associations: they facilitate the emergence of new partnerships, but inhibit deeper integration between hosts and guests (by favoring uncoordinated reproduction over synchronized ones). That is, easy come, easy go. #Endosymbiosis doi.org/10.1101/2025...

29.10.2025 15:41 👍 6 🔁 3 💬 1 📌 0
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Currency exchange in endosymbiosis: early on, hosts’ investments generate a fortune in guest growth; near full reproductive synchronization, that same investment buys much less. That is, cheap early gains, expensive late ones.

#Endosymbiosis #tradeoffs

doi.org/10.1101/2025...

29.10.2025 15:32 👍 0 🔁 0 💬 0 📌 0
Participants of the “Theory of Microbial Symbiosis” workshop standing together on the shore at the Hawaiʻi Institute of Marine Biology, with the ocean and trees in the background

Participants of the “Theory of Microbial Symbiosis” workshop standing together on the shore at the Hawaiʻi Institute of Marine Biology, with the ocean and trees in the background

Two researchers discussing their results shown on a screen

Two researchers discussing their results shown on a screen

A group of four researchers gathered around a blackboard with equations. One is pointing at the board, another is writing on it, a third is taking notes on paper, and the fourth is observing the discussion

A group of four researchers gathered around a blackboard with equations. One is pointing at the board, another is writing on it, a third is taking notes on paper, and the fourth is observing the discussion

A wooden building situated on the shore, with palm trees in the background. A group of people is gathered in front of the building, engaged in conversation

A wooden building situated on the shore, with palm trees in the background. A group of people is gathered in front of the building, engaged in conversation

This work stems from the “Theory of Microbial Symbiosis” workshop held last year at HIMB (Hawaiʻi Institute of Marine Biology), supported by the Gordon and Betty Moore Foundation @moorefound.bsky.social. Grateful to Joan Roughgarden and Lisa McManus for organizing such a fantastic workshop!

09.07.2025 19:00 👍 7 🔁 2 💬 1 📌 0

Great team work with Maria Martignoni, Lisa McManus, Taom Sakal, Armun Liaghat @armunliaghat.bsky.social ,
Bethany Stevens, Kyle Dahlin, Lucas Souza @lucasgenoma.bsky.social, Zoe Cardon, Cynthia Silveira, Seth Bordenstein @symbionticism.bsky.social, and Joan Roughgarden.

09.07.2025 19:00 👍 3 🔁 2 💬 1 📌 0
The top of the image shows a coral reef with a zoomed-in section highlighting the coral holobiont (comprising coral cells, bacteria, phages, fungi, and zooxanthellae). Below each component is its genetic material, collectively forming the "hologenome."

At the bottom, a wasp is shown as another example of a holobiont. On the left, the wasp hosts symbionts such as bacteria and phages. In the center, two wasps share some symbionts with each other and the environment. On the right, a wasp lineage undergoes speciation, resulting in two wasp species, each with a distinct symbiont composition.

The top of the image shows a coral reef with a zoomed-in section highlighting the coral holobiont (comprising coral cells, bacteria, phages, fungi, and zooxanthellae). Below each component is its genetic material, collectively forming the "hologenome." At the bottom, a wasp is shown as another example of a holobiont. On the left, the wasp hosts symbionts such as bacteria and phages. In the center, two wasps share some symbionts with each other and the environment. On the right, a wasp lineage undergoes speciation, resulting in two wasp species, each with a distinct symbiont composition.

We discuss the limits of current theoretical host-microbe models and outline 3 key areas for future work:

1) Modelling the nested structure of holobionts
2) Capturing microbial transmission dynamics in #holobiont populations
3) Understanding symbiont-driven host evolution and speciation

09.07.2025 19:00 👍 9 🔁 3 💬 1 📌 1
Preview
Theory of host-microbe symbioses: Challenges and opportunities Growing insight into microbial symbioses highlights the need to model these systems mathematically. We discuss three areas requiring theoretical advan…

Our article on the challenges and opportunities in studying host-microbe symbioses is now published in Cell Host & Microbe! @cp-cellhostmicrobe.bsky.social

www.sciencedirect.com/science/arti...

09.07.2025 19:00 👍 46 🔁 27 💬 2 📌 4
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Introducing carbon assimilation in yeasts using photosynthetic directed endosymbiosis

#NatureComms from Angad Mehta

www.nature.com/articles/s41...

18.07.2024 07:33 👍 4 🔁 5 💬 0 📌 0
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Impaired photoacclimation in a kleptoplastidic dinoflagellate reveals physiological limits of early stages of endosymbiosis Dinophysis dinoflagellates use plastids stolen from prey. Garric et al. show that these plastids cannot synthesize a complete phycoerythrin, a crucial photosynthetic protein. Dinophysis thus relies on prey ingestion for photoacclimation. It is noteworthy that some Dinophysis have acquired phycoerythrin synthesis genes from cryptophytes during evolution.

--PhD Publications by Sarah Garric--

#Photophysiology of the haploid form of the #cryptophyte Teleaulax amphioxeia
doi.org/10.1111/jpy....

Impaired photoacclimation in a #kleptoplastidic #dinoflagellate reveals physiological limits of early stages of #endosymbiosis

14.12.2024 06:35 👍 0 🔁 1 💬 0 📌 0
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Scientists discover first nitrogen-fixing organelle Modern biology textbooks assert that only bacteria can take nitrogen from the atmosphere and convert it into a form that is usable for life. Plants that fix nitrogen, such as legumes, do so by harbori...

'The organelle is the fourth example in history of primary endosymbiosis—the process by which a prokaryotic cell is engulfed by a eukaryotic cell and evolves beyond symbiosis into an organelle.'

12.04.2024 18:00 👍 4 🔁 2 💬 0 📌 0
Preview
Autoactive CNGC15 enhances root endosymbiosis in legume and wheat - Nature Nuclear calcium oscillations initiate plant–arbuscular mycorrhiza and nitrogen-fixing bacteria symbioses for nutrient acquisition, with a newly discovered autoactive CNGC15 mutant enhancing ...

You can find the study here:
Cook, N.M., Gobbato, G., Jacott, C.N. et al. Autoactive CNGC15 enhances root endosymbiosis in legume and wheat. Nature (2025). doi.org/10.1038/s415...

24.01.2025 07:37 👍 0 🔁 1 💬 1 📌 1
Preview
Scientists Recreate the Conditions That Sparked Complex Life Evolution was fueled by endosymbiosis, cellular alliances in which one microbe makes a permanent home inside another. For the first time, biologists made it happen in the lab.

Evolution was fueled by endosymbiosis, cellular alliances in which one microbe makes a permanent home inside another. For the first time, biologists made it happen in the lab.

www.wired.com/story/scient...

26.01.2025 13:59 👍 86 🔁 18 💬 3 📌 1
Preview
Scientists Re-ignite the spark that led to complex life Scientists recreated the origins of one of life's most important partnerships, uncovering how symbiotic relationships can evolve into powerful alliances.

Modeling endosymbiosis and the origin of organelles!

𝘙𝘩𝘪𝘻𝘰𝘱𝘶𝘴 𝘮𝘪𝘤𝘳𝘰𝘴𝘱𝘰𝘳𝘶𝘴—a fungus that infects corn and sunflowers—was microinjected with 𝘔𝘺𝘤𝘦𝘵𝘰𝘩𝘢𝘣𝘪𝘵𝘢𝘯𝘴 bacteria, which then successfully entered fungal spores and got passed to subsequent generations

Paper in Nature: www.nature.com/articles/s41...

27.01.2025 15:41 👍 11 🔁 2 💬 0 📌 0