Ludwig Cancer Research

The Invisible Billionaire: Daniel Ludwig Podcast Episode · Founders · March 23, 2025 · Bonus · 50m

Have some extra time this weekend? Check out this Founders Podcast episode on our founder Daniel K. Ludwig:

podcasts.apple.com/us/podcast/t...

#CanSky #OncoSky

Researchers led by Ludwig @harvard.edu’s @judithagudo.bsky.social Monica Cassandras & Xavier Sanchez have identified in preclinical studies a mechanism metastasizing triple-negative breast cancer cells engage to thwart immune attack & a drug that could disrupt it to curtail metastasis bit.ly/4r7kJBp

Congrats to Ludwig @ox.ac.uk Director Xin Lu and Chi Van Dang, CEO & scientific director of the Ludwig Institute for Cancer Research, who’ve received a Cancer Grand Challenges award as members of the ATLAS team to take on the challenge of “Cancer Avoidance”. Learn more: bit.ly/3N5Ac77

#CanSky

Obesity, adipose tissue, and systemic metabolism in cancer on the first session of #CFM_MetCanc. 
Speakers: 

Paul Cohen @rockefeller.edu 
Stephan Herzig @helmholtzmunich.bsky.social
@lydialynch.bsky.social @ludwigcancer.bsky.social

✍️ https://bit.ly/45jaORu 

Sponsored by @caixaresearch.bsky.social

Researchers led by Ludwig @unil.bsky.social’s @irvingmelita.bsky.social & Greta Maria Paola Giordano Attianese & EPFL colleagues have designed a remote-controlled CAR-T cell that can be quickly switched off with a pill for safety & then revived for cancer therapy by its withdrawal. bit.ly/4kPdVaa

Team led by Ludwig @unil.bsky.social’s Mikaël Pittet has discovered a gene expression program executed by tumor-associated neutrophils & a corresponding biomarker that drive tumor growth across human & murine cancers, identifying a potentially powerful target for cancer therapy. bit.ly/4r3zXIC

Tumor-derived CD13 helps cancer cells colonize the brain A new study published in Cell Reports shows that cancer cells activate CD13 to gain a foothold in the brain, long before tumors are established.

Tumor-derived CD13 helps cancer cells colonize the brain
🧠🧪🔬

Led by @lbejarano.bsky.social w/ many wonderful collaborators in @joycelab.bsky.social and in Lausanne 🙌

@cp-cellreports.bsky.social
@fbm-unil.bsky.social
@unil.bsky.social
@ludwigcancer.bsky.social

Article: www.cell.com/cell-reports...

We’re excited to announce the launch of the Ludwig Laboratory for Cell Therapy at Weill Cornell Medicine’s Sandra and Edward Meyer Cancer Center. The lab is directed by former Ludwig Lausanne Director George Coukos, an authority on tumor immunology & cellular immunotherapy. bit.ly/3ZdebG8

#CanSky

Congrats to Ludwig @unil.bsky.social's Ping-Chih Ho, recipient of the AAI-BD Biosciences Investigator Award for noteworthy early-career achievement in immunology research. He will get the award & give a lecture on April 16th at the annual meeting of the American Association of Immunologists.
#CanSky

A team led by Ludwig @unil.bsky.social’s @lbejarano.bsky.social & @johannajoyce.bsky.social has discovered that a protein made by cancer cells, CD13, helps them establish colonies in the brain—identifying a potential drug target for the prevention or treatment of brain metastases. bit.ly/4afX64r

Ludwig Oxford and the University of Oxford are seeking a mid-career stage scientist to join them as an Associate Member/Professor. Applications close at midnight on Friday, February 13. Apply here www.ludwig.ox.ac.uk/news/express...

Ludwig Princeton researchers led by Yibin Kang, Cao Fang and Mark Esposito report how a vitamin A derivative—retinoic acid—disrupts anti-cancer immune responses & the efficacy of a cancer vaccine + drug candidates to target both mechanisms for cancer immunotherapy.
bit.ly/4sItUdV

This essay, co-authored by Ludwig @unil.bsky.social @johannajoyce.bsky.social ,calls for a revitalized strategy for cancer research in Europe, identifying 7 policy priorities ranging from support for basic research & biotech startups to investing in education & cancer prevention. bit.ly/44fFCSw

The November 2025 edition of the Ludwig Link is here, and it's our largest ever! Catch up on the latest from Ludwig researchers, including awards, a new appointment & engaging conversations with three early-career scientists. Check it out online here bit.ly/3XfYVqV or download the PDF bit.ly/4poMsgA

Congratulations to Ludwig @ox.ac.uk’s @whitefishlab.bsky.social, who has been awarded an @acmedsci.bsky.social Professorship. This prestigious award provides up to £500,000 over 5 years to outstanding biomedical researchers who’ve recently taken a full professor position in the U.K.

bit.ly/3LICnNb

Join our team to contribute to discoveries with real translational potential, while developing your skills within Ludwig @oxfordcancer.bsky.social’s vibrant research community at one of the world’s leading centers for biomedical science.

Find out more and apply: ludwig.ox.ac.uk/jobs-and-study

A team led by Ludwig @weillcornell.bsky.social’s Chien-Huan Weng & Co-directors Taha Merghoub & Jedd Wolchok has found that a protein in the molecular matrix around cancer cells pushes anti-tumor CD8+ T cells into exhaustion & shown in mice it can be targeted for cancer therapy. bit.ly/49juiYV

Congratulations to the 39 Ludwig Cancer Research scientists included in the Highly Cited Researchers 2025 list compiled by @clarivate.com, which notes that its publication “identifies and celebrates individuals who have demonstrated significant and broad influence in their fields” of study.

#CanSky

Ready to take the next step in your scientific journey?

We have fully funded PhD studentships available for outstanding applicants interested in cutting-edge research at Ludwig @ox.ac.uk.

Learn more and apply by December 2.

bit.ly/47zOjcs

#CanSky #OncoSky

Researchers led by Ludwig @unil.bsky.social’s @johannajoyce.bsky.social, Spenser Watson and alumnus Jean Hausser have captured the temporal cellular dynamics of the tumor microenvironment over four weeks following tumor induction in a mouse model of breast cancer. bit.ly/4nCzA59

#CanSky #OncoSky

The Ludwig Institute for Cancer Research has been honored with admission to the Chancellor’s Court of Benefactors at the University of Oxford, which has since 2007 hosted a Ludwig Branch led by Xin Lu. Board Chairman Edward McDermott represented the Ludwig Institute at the ceremony.

@ox.ac.uk

Our congratulations to @skinnider.bsky.social!

Researchers at @ludwigcancer.bsky.social and CAMS Oxford Institute have made it to the final round of the 2025 @cancergrand.bsky.social Challenges! In a bid to make progress against #cancer's toughest challenges, 12 teams will be competing to receive a £20m award 🔬

Read more 👉 buff.ly/d5L04w9

🚨 Excited to share our new paper is out in Nature!
🔗 Reprogramming neuroblastoma by diet-enhanced polyamine depletion

Today marks the start of #PostdocAppreciationWeek, so we're kicking it off by sharing our first of three videos celebrating postdocs here at NDM 📽️🥼

Watch @whitefishlab.bsky.social and two postdocs in his research group at @ludwigcancer.bsky.social Oxford in the video below 👀👇

#NPAW2025

‼️See below terrific opportunity for a postdoc post with a leading group in Oxford, super exciting science! 🔥🔥👇

Congrats to Ludwig Institute Scientific Director Chi Van Dang, Ludwig Oxford Director Xin Lu, Ludwig Lausanne’s Mikael Pittet and Ludwig Stanford’s @michellemonje.bsky.social, whose teams have been picked as one of a dozen finalists for the prestigious @cancergrand.bsky.social award.
bit.ly/4mAhFvE

A team led by Ludwig Lausanne’s @johannajoyce.bsky.social & former postdoc @alvarezprado.bsky.social reports a potential drug target whose loss in certain GBM cells triggers antiviral alarms to stall cell proliferation & makes GBM tumors in mice more amenable to anti-cancer immunity.
bit.ly/4nhZ7Bj

Cancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com)‬ paper, Miranda Hunter (@mrndhntr.bsky.social‬) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2

Platelets are known for blood clotting, but that's not all. Researchers at @ludwigcancer.bsky.social Oxford have discovered another function - suppressing systemic inflammation. This information has the potential to improve cancer detection going forward 🩸

Find out more 👉 buff.ly/tzbL1yh