Michael Weintraub, MD

You know the protein craze is getting too much when protein-infused Pop Tarts are on the shelves.

conscienhealth.org/2026/02/23/m...

tomographic imaging techniques include dual-energy X-ray absorptiometry (DEXA), computed tomography scan (CT scan), and magnetic resonance imaging (MRI)

There are multiple methods to estimate body composition, each with their pros and cons.

www.mdpi.com/2075-1729/14...

DXA Versus Clinical Measures of Adiposity as Predictors of Cardiometabolic Diseases and All-Cause Mortality in Postmenopausal Women - PubMed DXA-derived estimates of abdominal adiposity in postmenopausal women may allow for substantially improved risk prediction of diabetes over standard clinical risk models. Larger DXA studies with…

DEXA-derived estimates of abdominal adiposity in postmenopausal women was a better predictor of cardiometabolic disease than traditional surrogates (BMI, waist circumference, waist-to-hip ratio) in older women.

pubmed.ncbi.nlm.nih.gov/34479738/

CagriSema demonstrates a1c reduction of 1.9% and weight loss of 14.2% in adults with type 2 diabetes, reported from the REIMAGINE 2 top-line data this week.

Automated insulin delivery, the integration of insulin pump with continuous glucose monitor is now the standard of care for Type 1 Diabetes 🤖💉📈

Why? It’s clearly superior in attaining greater diabetes control by way of Time In Range ⏱️🩸✅

researchprofiles.ku.dk/en/publicati...

Milestones in research related to the pathophysiology of the incretin hormones GIP and GLP-1 as
parent compounds for incretin-based medications for treatment of type 2 diabetes and clinical obesity

pubmed.ncbi.nlm.nih.gov/41547366/

What's new in ADA Standards of Care 2026?

Inclusion of continuous glucose monitoring (CGM) data when monitoring for disease progression among individuals with presymptomatic type 1 diabetes.

Recommendation 3.2 ADA Standards of Care 2026

diabetesjournals.org/care/article...

Mild autonomous cortisol secretion (MACS) is not a benign condition.

MACS carries increased risk of mortality with HR 1.52-1.77 compared to those with non-functioning adenomas, with death from cardiovascular disease, cancer and infection.

How to manage Post-Bariatric Hypoglycemia (BPH), according to a new consensus statement

Mild autonomous cortisol secretion (MACS) traditionally viewed as part of the continuum of Cushing syndrome is recognized as a distinct entity.

Only <1% of MACS processes to overt Cushing syndrome.
Genetic mutations for MACS and Cushing syndrome is different

www.vumedi.com/video/when-a...

Anabolic therapies hold tremendous potential for the treatment of osteoporosis. 💪🦴

Currently all treatments are injectables, but the are oral options on the horizon. 💉➡️💊

pubmed.ncbi.nlm.nih.gov/38578978/

A practical side-by-side comparison of the Tymlos and Forteo, the two anabolic PTH receptor agonists for osteoporosis.

Presented by Dr. Bilezikian

In a world where a publication becomes outdated immediately after it's published, a recent systemic review shows incretin-based medications dominate clinical trial development. But they are not the only potential mechanism.

pubmed.ncbi.nlm.nih.gov/40993341/

We should be screening everyone with hypertension for primary aldosteronism, according to the recently released Endocrine Society guidelines.

Follow this diagnostic algorithm

Full guidelines: academic.oup.com/jcem/article...

How to individualize obesity medication treatment depending on obesity-related conditions.

Great summary by the newly released update to the AACE Evaluation and Treatment of Adults with Obesity 2025 Consensus Statement

www.endocrinepractice.org/article/S153...

Developing clinical practice guidelines is quite a process.

The GRADE format methodology translates evidence to medication decision-making recommendations after performing systemic review of the available evidence.

www.bmj.com/content/389/...

A higher BMI is correlated with increased risk of overall mortality. It follows the same overall curve as higher cholesterol and blood pressure, as illustrated in these graphs 📈

Controlling any and all of these risk factors lowers our overall risk of death.

pubmed.ncbi.nlm.nih.gov/28489290/

Obesity rates have skyrocketed starting in the 1970s now reaching 40% in the United States.

"It seems highly unlikely that the obesity epidemic can be explained by a widespread drop in willpower happening in the late 1970s."

www.cell.com/cell/fulltex...

Special Edition - ADA Scientific Sessions 2025 — Diabetes Core Update In this special edition of Diabetes Core Update we present a special podcast recorded live at the ADA Scientific Sessions by the editors of Diabetes Core Update, Diabetes Care On Air, Diabetes Bio,…

A collection of all my favorite podcasts to stay up to date in Diabetes Care

Check out this Marvel-style crossover episode hosted at ADA.

overcast.fm/+AABFhuN39pM

Rates of obesity of BMI 30-40 have had a mild increase over the last 20 years.

Rates of severe obesity BMI > 60 has dramatically risen- this graph is impressive.

Slide by Dr. Satya Dash at #ENDO2025

Pheochromocytoma survival curves are dismal, particularly in those with metastatic disease. We need better treatments for these patients.

Excellent lecture by Dr. Camilo Jimenez at #ENDO2025

Multiple benefits of GLP1s in reducing residual risk in those with type 1 diabetes.

Excellent talk by Dr. Kaitlin Love at #ENDO2025

GLP1 agonism prevents cardiovascular disease through both direct and indirect vascular effects
#ENDO2025

Studies showing benefits of GLP1 agonists in type 1 diabetes are accumulating.

Modest A1c reduction but impressive reductions in total daily insulin dose and weight reduction.

#ENDO2025

Retatrutide may be the most hotly anticipated GLP-1 based medication in development 🔥💊, but others are not far behind 🏃.

A triple agonist, UBT251, is under development in China 🇨🇳 and also mimics GLP-1, GIP, and glucagon 🧬⚗️.

“Food noise” is the “incessant mental chatter” or “constant rumination” about food.

It is increasingly recognized as a phenomenon particularly with its profound elimination with GLP1 treatment.

New Nature review: www.nature.com/articles/s41...

Great overview: conscienhealth.org/2025/07/lift...

“If you treat someone’s blood pressure or cholesterol you don’t get improvements in quality of life. You treat their weight you get all the benefits."

"That is the power of treating obesity.”

Inspiring talk by Dr. Lou Aronne on the clinical implications of CagriSema at #ADASciSessions #ADA2025

The long awaited triple agonist retatrutide phase 3 data is still pending ⏳🧪.

However, a body composition subanalysis of the phase 2 data is newly published 📄 showing lean mass loss of 38% of total weight loss 💪📉.

The etiology of obesity is most often multifactorial- a combination of environmental factors and genetic predisposition among thousands of genes.

However, a portion of cases are due to a single genetic cause, such as in the leptin-melanocortin pathway.

academic.oup.com/edrv/article...