@charliemcternan
#UKRIFLF and Group Leader in the Physical Sciences, Francis Crick Institute, Senior Lecturer, KCL. Supramolecular Chemist; Molecular Machines and Capsules; Supramolecular Therapeutics; Peptide Chemistry and Chemical Biology
Delighted to see our work on anion-switchable palladium cages, used to purify single pharmaceuticals from complex mixtures, out in ACIE today: onlinelibrary.wiley.com/doi/full/10.... - great work from lead author Zhe, and brilliant crystallography from Tanya!
Our new video, created by Stuart Jantzen (Biocinematics), depicts the original Maxwell’s Demon thought experiment 😈 tinyurl.com/3ja25xfz, the archetypal information ratchet that inspires how we design molecular motors & pumps: tinyurl.com/msn8c2an; tinyurl.com/yj53rfvm; tinyurl.com/557vcubt 👹
Oh look, we made a new spinout company! Repeat academic founder Simon Boulton is planning to exploit the weird trick that cancer cells use to keep replicating indefinitely www.crick.ac.uk/news/2026-02...
We need to be shouting about the effects of this on junior researchers from the roofs, writing to our MPs. We are risking a "missing generation" of researchers.
Our latest collaborative preprint from the group and @kilbinger-group.bsky.social is out - tinyurl.com/3bbrfyhw - we've been looking at creating stably folded, helical, and polyfluorinated transmembrane channels with rates of water transport exceeding Aquaporins. Great to see the manuscript up!
Out today in @natchem.nature.com 😃 Huakui, @stefanborsley.bsky.social @benjaminoacid.bsky.social & co illustrate why catalysis-driven motors (like motor proteins) can't use designs based on light-driven motors or molecules-that-rotate-through-multi-reaction-sequences www.nature.com/articles/s41...
We are recruiting! Postdoc positions now open in our laboratory - please come join us in making mechanically interlocked materials for biological applications🧫🛠🔗🧪☘! Applications through advert link below lnkd.in/e7SpdkEQ
Please reach out with any informal inquiries or questions 💬
Come work with us at the @ciqus.bsky.social We are looking for a PhD candidate with motivation for organic synthesis in the ERC Synergy project “Covalent Chaotropic Membrane Transport for Biotherapeutic Delivery” (CARAMEL). Sharing ❤️ All details here 👉 euraxess.ec.europa.eu/jobs/398337
When liquids freeze, ions normally grind to a halt — but not in our new materials!
Our latest paper in @science.org shows how organic salts can keep the same ionic conductivity mechanism as they transform from liquid to solid.
🔗 www.science.org/doi/10.1126/...
@ox.ac.uk @ajavestro.bsky.social
Congrats to Dr Aisha Bismillah @anbismillah.bsky.social on receiving the inaugural MASC/WISC EDIA Award 2025!
@wisuprachem.bsky.social
#MASC2025
#RSC_MASC
Prof Paul McGonigal @paul-mcgonigal.bsky.social receives the 2025 Bob Hay Lectureship 🏆 Congratulations, Paul!
#MASC2025
#RSC_MASC
🚨WISC is excited to announce we are changing our name to Women and Inclusion in Supramolecular Chemistry!
➡️ www.womeninsuprachem.com
#WomeninSTEM
#EDI
#SupramolecularChemistry
#ChemSky
Delighted to see our work on dual cavity cages online @chemicalscience.rsc.org - tinyurl.com/yatjzpnc - we explore how subtle changes in peptide sequence and chirality transform cage formation and isomer selectivity, with unexpected results. Congratulations to @benebarber.bsky.social Ellen and Leah!
Great to see our paper on photoswitchable anion channels with the Wallace Lab (KCL) online - congratulations Javid, Kharina, Sam and Adi! onlinelibrary.wiley.com/doi/10.1002/...
Triply addressable ion channels, and we use these to construct a set of molecular logic gates.
New preprint from the group is out - tinyurl.com/yyadfcdv - Zhe has been working on anion switchable palladium cage systems, and used them for separating active pharmaceuticals!
🚨 Final reminder to submit your abstract for an oral and/or poster presentation for a chance to showcase your research at this year’s MASC meeting (15th–16th Dec 2025) at the Open University, Milton Keynes!
⚠️ Deadline this Friday, 7th of Nov 2025
More details on mascgroup.co.uk/masc-2025-ab...
I'm advertising a funded opportunity for a postdoc to join the Fielden Research Group for 24 months: www.jobs.ac.uk/job/DPC150/r...
We're looking for a researcher with expertise in supramolecular and/or colloid chemistry to help kick start our ERC-funded project into dynamic emulsions. 😃
We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.
Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.
Apply now ➡️ www.crick.ac.uk/careers-stud...
2026 PhD recruitment is now open.
As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website:
www.crick.ac.uk/careers-stud...
Join us at The Open University, Milton Keynes on the 15th and 16th of December 2025 for this year’s RSC Macrocylic and Supramolecular Chemistry meeting!
Registration and abstract submission are now open (key deadlines below)
More on mascgroup.co.uk/masc-2025-ho...
#RSC_MASC
#RSC_MASC_2025
(1/2)
Happy to share this cover finally online in the September issue of chem. Thank you @vivesgui.bsky.social and @msollogoub.bsky.social for the design and drawing of such nice cover👏👏👏
Call for Applications / Ausschreibung
Springboard for an international scientific career! 🧬🧪🔭⚛️🧠🌱 Call for #MaxPlanckResearchGroups launched; applications are possible until October 14, 2025 www.mpg.de/max-planck-r... #ScienceCareer
Massive congratulations to @zarikyusaf.bsky.social who passed his PhD viva today 🎉🎉 Big thanks to examiners @charliemcternan.bsky.social and Ramon Vilar, and to co-supervisor @lewischemistry.bsky.social who made the trek down for the big event!
📣 Call for Abstracts - vMASC 📣
We are currently inviting abstracts from all early-career researchers (Master’s, PhD, PDRA) for oral presentations in 2025/2026 as part of our monthly vMASC seminar series.
Submission deadline 📆 18th Aug 2025
Find out more on mascgroup.co.uk/vmasc-4/vmas...
Light-Activated Metal-Dependent Protein Degradation (LAMP-D)
Imagine a small molecule that degrades a target protein like PROTACs, but does so independently of any of the host cell's degradation machinery, so you can go and do targeted protein degradation in gram-negative bacteria: doi.org/10.26434/che...
🔊 We are looking for a motivated PhD candidate to work @ciqus.bsky.social in drug delivery by superchaotropic boron clusters.
We offer a great working environment, in an excellent center and an exciting research field, www.nature.com/articles/s41...
euraxess.ec.europa.eu/jobs/360505
Sharing 🙏
Great to see our Review on using Peptides to build Discrete Supramolecular Architectures online at Angewandte @angewandtechemie.bsky.social ! onlinelibrary.wiley.com/doi/10.1002/... with a great Frontispiece from Ben! Congratulations Ben Ellen and Leah!
Come and join our team at @crick.ac.uk
Help commercialise phenomenal science!
#biotech #techtransfer
