Dr Yvonne Adams 🏴󠁧󠁢󠁳󠁣󠁴󠁿🇩🇰🏳️‍🌈

I shall give it a try then!

I’m curious, do you find it is consistently returning this level of depth and accuracy, or does it vary or decline? I ask as I’ve experienced inconsistencies with other models and platforms. Some monetise accuracy. I’ve not tried this one yet.

I’m also disappointed there’s no characterisation of the endothelial cells showing they are indeed endothelial. The lack of polarisation under flow for the iBMEC is puzzling. Also that’s a very leaky if 2 MDa is crossing (iEC).

Very late in the day but I’m gutted I can’t go to see Sharon van Etten and The Attachment Theory as Store Vega tomorrow 🥲 Stupid injury!! So my tickets are on resale. secure.ticketmaster.dk/rs/554433/lr... #Copenahgen #ticketmaster

But how do you deal with publishers unwilling to address fraudulent literature?

Out of office emails on. Emails turned off on phone. Now it’s time to head to the airport, relax and enjoy the Christmas vacation 🎄#merrychristmas

First lecture of the season done and dusted. Malaria variant antigens. Managed to shoe-horn some BBB and organoids in there! 🤣 #malaria #organoids

Would love to join, Im using blood-brain barrier organoids and 3D blood CSF barrier models to study infectious diseases such as malaria and neuroborreliosis.

👋 l’d like to be included

Nice afternoon spent learning about the clinical status of tick borne diseases here in Denmark. Still lot convinced by the Pfizer vaccine though #borrelia #tbe #tickborneencephalitusvirus

With the influx of new users, followers (thank you!), I admittedly need to make use of it more. So here’s some helpful info on BlueSky. I really hope to get it set up to make it the cool paper finding platform that the other place used to be (and limit viewing of non-work related posts).

#neuroskyence I'm in a paper drought. What is the most interesting (and particularly the most under-rated) paper or pre-print on your radar?

Second conference of 2024! This time my side-pathogen #borrelia and will be presenting my work on using blood-brain barrier #organoids to investigate #neuroborreliosis It’s all about the barrier!! Onwards to Fyn and #Nordtick

Dear #neuroscience #infectiousdisease #lymedisease hive mind!! Does anyone have info on Lyme disease specific funding that isn’t geolocked? Any info greatly appreciated 🙏

Happy #FluorescenceFriday Normally, I'm all about the endothelium, but this time it's some lovely tight-junctions from an epithelial monolayer. There are multiple barriers in the human brain and now we are focusing on the blood-CSF barrier #malaria #neuroscience

In 2021 I was awarded funding by the Danish 3Rs/Landbrugsstyrelsen to work on BBB organoids. We've shown they can model cerebral malaria and tissue tropism in Lyme disease. You can read more about it in more detail here: bit.ly/3XbVnUg and here bit.ly/3167j5q
#borrelia #neuroscience #malaria

We are new on @bsky.app. You will see news from our institute from now on here.

Here’s hoping the #ICAM1 hive-mind can help!! trying to find a-ICAM-1 Abs - we have 15.2 R1/1 8.4A6. wanted to try and get My13 and 7F7….except they’ve been discontinued. Does anyone know of good Abs against ICAM-1 D1 and D2 #vascular #endothelium #leukocytes

- YouTube Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

While I love the idea of JoVE, it's expensive and very spammy. We have tried to remedy that in my group by making video protocols and hosting them on YouTube www.youtube.com/watch?v=ct12... always happy to talk techniques and more videos to come #neuroscience #malaria #infectiousdiseases

Images of presenters and attendees at the 1st mini-symposium on 3D cell culture and organoid research held at ISIM, University of Copenhagen

Fantastic afternoon of all things 3D cell culture/organoids/spheroids. So many interesting talks covering a range of tissues and organs, from my personal favourite the BBB, to the retina, intestinal organoids, tonsil/thymus organoids, liver and full thickness skin models 🤯 #malaria #neuroscience

Throwback to that time we blinded our parasites using the characters from Beverly Hills 90210! Fun times! Just wish we could’ve used those names in the paper instead of HB3VAR03 etc 🤣 #malaria #parasitology #neuroscience

By comparing multiple isolates from Lyme neuro, non-Lyme neuro and N America, we observed only those from Lyme neuro patients crossing the barrier

…and we don’t just use them for cerebral malaria. We also use them to investigate Lyme neuroborreliosis more commonly found here in Europe.

In doing so, this leads to swelling and BBB dysfunction

By utilizing ICAM-1, a subset can enter endothelial cells and cross the BBB

So what do we do in my lab? 🤔 We use BBB-organoids to study how RBCs infected with malaria parasites interact with ICAM-1….

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Hmmm where are all the blood-brain barrier and blood-CSF barrier peeps? #AcademicSky #MedSky #WhatsScience

👋 finally joined! Hopefully the #neuroscience #parasitology #immunology scene is as enjoyable as the other place. Here to talk all things neuro, malaria, borrelia and how to use 3D and organoid models of the neural barriers to study infectious diseases.