Christoph Gunkel

Outpacing E. coli: Development of Vibrio natriegens as a Next-Generation Cloning Host https://www.biorxiv.org/content/10.64898/2026.02.11.705132v1

Molecular basis of the biogenesis of a protein organelle for ethanolamine utilization EutQ governs enzymatic cargo encapsulation within the protein shell to drive Eut microcompartment biogenesis in Salmonella.

🚨📣 Pathogenic bacteria assemble protein-based microcompartments to digest ethanolamine in the gut, a process essential for their growth and survival and a potential target for antimicrobial strategies. doi.org/g95j7q
Synergy of multiple UoL Shared Research Facilities
also 🚨📣 @makaefer.bsky.social

Ready for market: Engineered yeast boosts clean, cost-efficient chemical production Building on their success developing a cleaner way to make valuable organic acids, researchers from the Center for Advanced Bioenergy and Bioproducts Innovation (CABBI) have pushed one product closer to commercialization with a major upgrade in yield.

Engineered yeast now produces succinic acid from plant sugars with an 85% yield, significantly lowering production costs and advancing sustainable alternatives to petrochemical-based methods. doi.org/g9wn2w

Turning ocean carbon into biodegradable plastic System is first to pull carbon dioxide from the ocean and convert it to valuable product

Researchers have invented a system that captures carbon dioxide from ocean water and converts it to succinic acid, a key monomer used to make the commonly used biodegradable plastic polybutylene succinate. cen.acs.org/environment/... #chemsky 🧪

Advances in metabolic engineering of Vibrio natriegens as an unconventional host for biotechnology

doi.org/10.1016/j.ym...

#MicroSky: SynBIOL: Engineered E. coli makes creatine! By adding AGAT & GAMT plus an ATP regeneration system, Shen et al achieve >5 g/L CR with high productivity. A new platform for ATP-hungry metabolite production! doi.org/10.1111/1751...

Left: The atomic model of the PS2 lattice is shown in top and side views. PS2 hexamers are repeated in the 2D sheet with a lattice constant of 176 Å. Each PS2 monomer is colored and labeled separately within the hexamer, which repeats throughout the lattice (with pore dimensions highlighted). The side view of the lattice shows the smooth surface facing the extracellular space and rough surface with coiled-coil segments protruding towards the MM. Top right: Interactions at the hexameric and trimeric interfaces are stabilized by both hydrophilic and hydrophobic residues. Bottom right: A cell envelope tomogram was used to overlay the cryo-EM structure of the S-layer onto the in situ S-layer tomographic density. A single slice of the tomogram is shown, with the overlayed PS2 S-layer lattice in green and the tomogram in grayscale. The S-layer (surface layer), MM (mycomembrane), IM (inner membrane), and Cytosol are labeled.

The unique #CellEnvelope of #corynebacteria: @tbharat-lab.bsky.social &co map the C. glutamicum cell surface, revealing a patchy S-layer & specific assembly of the PS2 protein, thereby informing our understanding of cell envelopes that contain #MycolicAcids @plosbiology.org 🧪 plos.io/3Y6JNgw

Most bacterial gene families are biased toward specific chromosomal positions The arrangement of genes along bacterial chromosomes influences their expression through growth rate–dependent gene copy number changes during DNA replication. Although translation- and transcription-...

I was waiting two years to see this out!! The genomic location of bacterial genes is not random!!! Congratulation on the authors (Martin Lercher and Team!). www.science.org/doi/10.1126/...

BIOspektrum issue 1/25 is on its way to your📫 This edition features the latest news from across the biosciences along with our special coverage on the Microbe of the Year 2025 #MdJ Corynebacterium glutamicum🦠🧪🏆
t1p.de/egenx