Shafi Kuchay

@shafikuchay

Human health, Liver health, Lifestyle 👻 New Delhi, India

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Posts 20.04.2025
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Latest posts by Shafi Kuchay @shafikuchay

Our paper online now #MASH

journals.physiology.org/doi/full/10....

07.05.2025 15:00 👍 5 🔁 1 💬 0 📌 0

Damaged hepatocytes interact witn gamma-delta T cells, and active immune apparatus in #MASH
journals.physiology.org/doi/abs/10.1...

23.04.2025 14:03 👍 7 🔁 2 💬 0 📌 0

Carvedilol sensitizes chemotherapy by targeting STING to boost anti-tumor immunity Dang et al. discover carvedilol, a clinically approved β-adrenergic receptor antagonist, as a STING activator through high-throughput screening. Mechanistically, carvedilol promotes STING dimerization to enhance type I interferon responses. The findings provide the basis for repurposing carvedilol in the therapy of STING-related diseases.

Carvedilol sensitizes chemotherapy by targeting STING to boost anti-tumor immunity

22.04.2025 14:38 👍 7 🔁 1 💬 0 📌 0

MASLD targets. Learn how different therapies work in #MASH treatment.

journals.physiology.org/doi/abs/10.1...

22.04.2025 10:11 👍 4 🔁 1 💬 0 📌 0

My continued biomedical education
#MASLD #MASH

Pathophysiological underpinnings of metabolic dysfunction-associated steatotic liver disease

Gut (microbiota)-liver axis

#HepaticStellateCell #Pericyte #YAP/TAZ #GLutaminolysis #Fibrosis

#AJPCellPhys 2025
journals.physiology.org/doi/abs/10.1...

19.04.2025 19:08 👍 9 🔁 3 💬 1 📌 1

Our latest invited review on the pathogenesis of MASLD.

journals.physiology.org/doi/abs/10.1...

20.04.2025 02:29 👍 14 🔁 4 💬 0 📌 0

Great analysis of the review 👏🏼👏🏼

20.04.2025 02:06 👍 5 🔁 1 💬 0 📌 0