"Alguien está equivocado en internet" (xkcd). ¿Qué pasa cuando lo equivocado son los libros, y el error proviene de un argumento de Einstein? Acompáñeme en la demostración del teorema de Nernst (tercer principio de la termodinámica).
🆕🧵⬇️
Nature reports on how researchers are studying why mitochondria are moving between cells and whether the process can be harnessed to treat cancer and other diseases. 🧪
This is figure 1, which gives an overview of cohort construction, model development and performance assessment for 10-year incident CAD risk meta-prediction in the UKBB.
A study in Nature Medicine shows that a meta-prediction framework integrating polygenic risk scores spanning multiple conditions and nongenetic factors had superior performance in predicting the 10-year risk of coronary artery disease. go.nature.com/4igXqAJ 🔒
Intensive Home Blood Pressure Lowering in Patients with Advanced CKD
bit.ly/4dZXB1t
#CKD
A Nature analysis shows the 25 highest-cited papers published in the 21st Century and explores why they are breaking records. #Academicsky 🧪
Mineralocorticoid Receptor in Endothelial Cells Contributes to Vascular Endothelial Growth Factor Receptor Inhibitor-Induced Vascular and Kidney Damage
academic.oup.com/ajh/article/...
🔒
What Is Dialysis? JAMA Patient Page
Dialysis is a medical treatment for individuals with kidney failure. This JAMA Patient Page describes dialysis options for people with kidney failure and the potential complications of dialysis. https://ja.ma/3FtkPRP
The March 2025 cover of AJKD celebrates #WorldKidneyDay!
Check out the plain-language summaries - what inspired each study, basic approach taken, what was learned, and why it matters:
bit.ly/41kJWO5
@WorldKidneyDay
Brand new infographics about Cardiovascular Risk Factors and Multiomics & Artificial Intelligence on Cardiovascular Research from @atheronet.bsky.social
🍋 Cooked in a zesty lemon marinade, this quick & easy chicken casserole makes a great #KidneyFriendly family dinner. Full recipe: kidneycareuk.org/get-support/...
This recipe is:
▶ High protein
▶ Low phosphate
▶ Low potassium
▶ Low salt
In a randomized trial including 365 patients, combination of CAC with a primary prevention strategy in intermediate-risk patients with a family history of CAD was associated with reduction of lipids and slower plaque progression at 3-year CCTA jamanetwork.com/journals/jam...
ALDH1A1 loss promotes calcification in aortic valves, but retinoic acid receptor agonists can effectively prevent this process.
by Rosa M, Dupont A (...) Van Belle E et 20 al. in Circulation #MedSky
📖 read the article: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.124.071954
Age at Which #CAC Becomes Detectable Among Young Adults varies substantially by race, sex & number of ASCVD RFs
#CardioSky #YesCCT
#Circulation
www.ahajournals.org/doi/10.1161/...
@ahajournals.bsky.social @michaeldshapiro.bsky.social @ljshaw.bsky.social @shoaclarke.bsky.social
New research out in @science.org from @hongbo919.bsky.social & @ksusztak.bsky.social (@PennKidney/ @penngenetics.bsky.social) provides a genetic map of kidney function & introduces a kidney multiome-based genetic scorecard for disease diagnostics & therapeutic development tinyurl.com/ubkutd4s
📢Do you or a family member have #KidneyDisease, #HighBloodPressure or #Diabetes?
📒 We would like to hear about what information you have received about your #kidneys - what was good & what could be improved!
🔗https://app.onlinesurveys.jisc.ac.uk/s/salford/phase-1-patient-survey
🙌Thank you!
Prevalence of Severe Mental Illness and Its Associations With Health Outcomes in Patients With CKD: A Swedish Nationwide Study
bit.ly/3Xj4zsy #OpenAccess
#CKD #VisualAbstract
COL4A5 Intronic Variants at Third to Fifth Nucleotides Cause Alport Syndrome pubmed.ncbi.nlm.nih.gov/39990911/
In recognition of #WorldKidneyDay on March 13, the editors present a collection of AJKD articles that highlight kidney disease research across the world:
https://bit.ly/3EUhrPN (FREE)
@WorldKidneyDay
Plastics have infiltrated every recess of the planet, including your lungs, kidneys and other sensitive organs. Nature reports on the work scientists are doing to understand their effects on your health. 🧪
SGLT2 inhibitors reduce cardiovascular risks more effectively in older adults, while GLP-1 receptor agonists benefit younger individuals.
by Hanlon P, Butterly E (...) McAllister DA et 19 al. in JAMA #MedSky
📖 read the article:
Before we start, a few reminders! Are you new to #NephJC? Not sure what to do or how this works? Here is a quick rundown- pic made by @sstoneman.bsky.social
Improving #BloodPressure in High-Risk #CKD Patients using an Interdisciplinary Remote #Hypertension Program
#VisualAbstract by @drpriyajohn
www.kireports.org/ar...
Low-carb diets win against low-fat diets (except in most important measure):
- reduce HbA1c, fasting glucose, and triglycerides 💪
- superior weight loss 💪
- increased HDL 💪
Big problem: reductions in diabetes medication!
--> No money to be made 😭
doi.org/10.7759/cure...
Million Veteran Program: dietary cholesterol intake was linearly associated with greater risk of MI
#CardioSky #MedSky #JAHA
www.ahajournals.org/doi/10.1161/...
@erinmichos.bsky.social @michaeldshapiro.bsky.social @drmarthagulati.bsky.social @psatishmd.bsky.social @drlipid.bsky.social
The risk of venous thromboembolism (VTE) varies across different types of hormonal contraceptives, with the highest risk associated with combined pills containing third-generation progestins.
ja.ma/4jLfmpj
#MedSky
These findings support the use of sodium-glucose cotransporter-2 inhibitors in CKD, irrespective of frailty, multimorbidity, or polypharmacy.
CJASN 19(9):p 1119-1129, September 2024
#podocytetalk #Nephpearls #CKD #nephsky
journals.lww.com/cjasn/fullte...
Clonal hematopoiesis is a risk factor for cardiovascular disease, but the mechanisms remain unclear.
Wenli Liu et al. generated a mouse model & found small number of mutant macrophages that can affect WT cells to promote atherosclerosis & destabilize plaques: https://www.jci.org/articles/view/182939
Purinergic receptor P2X7 regulates interleukin-1α mediated inflammation in #chronickidneydisease in a reactive oxygen species-dependent manner
doi.org/10.1016/j.kint.2024.10.024
#OpenAccess #CKD #NephSky #MedSky
