Universal method could transform the future of bone transplantation Lund University. In brief: Overall, the study shows that it is possible to create safe, cell-free tissue structures that effectively help the body build new bone tissue. The results meet key requireme...

🦴🧫 Over 2M people/year need bone transplants. A new @pnas.org study by @cto-bourgine.bsky.social shows how a cell-free cartilage graft can safely guide bone repair without strong immune reactions in animal models - an off-the-shelf step toward human studies.

www.stemcellcenter.lu.se/article/univ...

Human bone marrow organoids: emerging progress but persisting challenges Organoid systems hold promise as miniaturized in vitro platforms that model developmental and pathological processes. However, the engineering of human bone marrow organoids (BMOs) has been a long-sta...

Happy to share this opinion piece, on the emergence of bone marrow organoids 🥳 ! A much more difficult exercise than I thought, but curious to hear your thoughts. Are we on the right path towards replicating human bone marrow features? 😶‍🌫️

www.cell.com/trends/biote...

Congrats to @laura-rabanal.bsky.social and Lea Chicoisne (from @consigliocr.bsky.social lab) for their awarded project "Influence of sex steroids on bone metastasis development in lung cancer"! 🤩
They receive the 1st prize from the Wallenberg Center Research school evaluation board!!

Great initiative! Thank you @Laura Rabanl Cajal and @Sara Gonzalez Anton from your lab for participating!

Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Glad to share our latest publication, demonstrating the generation of human tissue graft edited in their composition leading to tailored regenerative capacities. The strategy could lead to custom "tissue therapies" promoting endogenous repair. Congrats to all!🦴🤩
elifesciences.org/articles/969...

Congrats, nice story!