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Gust Bilcke

@gustbilcke

Experimental biologist dabbling in bio-informatics. Focus on algae and their fascinating life cycles 🦠 Post-doc @ VIB/UGent Belgium (FWO fellowship)

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27.11.2023
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Latest posts by Gust Bilcke @gustbilcke

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Evolutionary cell biology comes of age Summary: This Perspective discusses how the discipline of evolutionary cell biology, by integrating evolutionary theory, comparative physiology and modern molecular approaches, works to understand how...

Thanks @jcellsci.bsky.social for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation πŸ§ͺ🌍

W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social

journals.biologists.com/jcs/article/...

19.12.2025 16:13 πŸ‘ 83 πŸ” 33 πŸ’¬ 0 πŸ“Œ 5

This paper is the result of a fruitful collaboration between the Ferrante & Iudicone labs (Naples, Italy - @luciacampese.bsky.social) and the Vyverman and Vandepoele groups (Ghent, Belgium) @vandepoelelab.bsky.social . Shout-out to @fwovlaanderen.bsky.social for funding this research πŸ”¬

18.11.2025 06:31 πŸ‘ 0 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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Conserved genetic markers reveal widespread diatom sexual reproduction in the global ocean - Nature Communications Diatoms dominate the oceans, yet sexual reproduction - key to bloom dynamics and species evolvability - is rarely observed. Using a lab-to-field approach, this study presents conserved markers applica...

In our latest, we tackle a long-standing conundrum: when and where do diatoms reproduce sexually? Using a lab-to-field strategy, we designed conserved sex markers applied to microcosms & Tara Oceans metatranscriptomes, revealing widespread sex in the global ocean. Read all about it now in NatComm:

18.11.2025 06:31 πŸ‘ 6 πŸ” 3 πŸ’¬ 1 πŸ“Œ 0

With @floravincent.bsky.social @serenaflori.bsky.social @darjabelisova.bsky.social @cleymanarthur.bsky.social @vandepoelelab.bsky.social @ansgargruber.bsky.social @nic-poulsen.bsky.social @sinkingdiatom.bsky.social and many others

01.07.2025 07:25 πŸ‘ 3 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Looking back on last week's Molecular Life of Diatoms conference 🌊. Honored to be hosting this tight-knit, creative and collaborative community in Ghent! Topics ranged from single-cell approaches, imaging breakthroughs, new insights into photosynthesis and symbioses etc. #protistsOnSky #MLD8

01.07.2025 07:17 πŸ‘ 18 πŸ” 2 πŸ’¬ 1 πŸ“Œ 1
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In the last talk of the #MLD8 conference, Peter Kroth gave an excellent overview of recent advances on diatom transcription factors, and how they regulate surface adhesion and light sensing πŸ§¬πŸ‘‹

26.06.2025 13:35 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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1/27 We have a new paper out! Turns out that snowflake yeast have been hiding a secret from us - they've evolved a (very!) crude circulatory system. Not with blood vessels or a heart, but through spontaneous fluid flows powered by their metabolism. πŸ§ͺπŸ”¬

www.science.org/doi/full/10....

24.06.2025 16:52 πŸ‘ 356 πŸ” 146 πŸ’¬ 14 πŸ“Œ 25

Using sexual reproduction markers identified from scRNA data, Arthur Cleyman developed new tools to transform Cylindrotheca closterium and make β€œpheromone sensing” lines. Cool 😎 #MLD8 @gustbilcke.bsky.social

24.06.2025 13:33 πŸ‘ 4 πŸ” 3 πŸ’¬ 0 πŸ“Œ 0

Single-cell RNA sequencing of two diatom species shows clear patterns of expression during sexual reproduction, shedding light on the mechanisms involved. Great student talk by Nadine Rijsdjik @ #MLD8 @gustbilcke.bsky.social

24.06.2025 13:14 πŸ‘ 3 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0
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The design and synthesis of whole synthetic chromosomes (and yes, for diatoms) is now possible. The future is here. (Bogumil Karas @ #MLD8)

24.06.2025 12:06 πŸ‘ 6 πŸ” 1 πŸ’¬ 0 πŸ“Œ 0

Predators come along and crunch off the apex/long axial spines of pennate diatoms (!). Sometimes it’s catastrophic for the diatom, but they’re often totally resilient and can divide again after two days. Eventually the shape is restored. Darja BelisovΓ‘ at #MLD8

23.06.2025 13:31 πŸ‘ 3 πŸ” 1 πŸ’¬ 1 πŸ“Œ 0
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Day 1 of #MLD8 - with an amazing talk by @nic-poulsen.bsky.social on diatom adhesion and motility, describing proteins found in diatom glue @mldiatoms.bsky.social

23.06.2025 07:56 πŸ‘ 6 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

Only few days to register with an early bird discount for the famous Molecular Life of Diatoms conference, coming to beautiful historic Ghent, Belgium in June! 🏰 🦠

05.05.2025 21:20 πŸ‘ 2 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0
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Cathepsin X is a conserved cell death protein involved in algal response to environmental stress Phytoplankton are responsible for half of the global photosynthesis and form vast blooms in aquatic ecosystems. Bloom demise fuels marine microbial li…

πŸ“£ We are excited to share our latest paper about Cathepsin X, a new algal cell death gene, led by @aviamizrachi.bsky.social and @maisadeh.bsky.social, published in Current Biology @currentbiology.bsky.social www.sciencedirect.com/science/arti... 1/3 >>

24.04.2025 06:32 πŸ‘ 12 πŸ” 7 πŸ’¬ 1 πŸ“Œ 0
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The abstract submission deadline for the 8th edition of the Molecular Life of Diatoms conference has been extended: the new deadline is 27th of April 2025. Don’t miss a chance to present your breakthrough research! www.vibconferences.be/events/molec...

22.04.2025 09:20 πŸ‘ 2 πŸ” 2 πŸ’¬ 0 πŸ“Œ 1
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DiatOmicBase: a versatile gene‐centered platform for mining functional omics data in diatom research In recent years, diatoms have become the subject of increasing interest because of their ecological importance and their biotechnological potential for natural products such as pigments and polyunsat...

#diatoms #genomics #resources DiatOmicBase: a versatile gene-centered platform for mining functional omics data in diatom research @theplantjournal.bsky.social onlinelibrary.wiley.com/doi/10.1111/... joint work with @afalciat.bsky.social

17.03.2025 09:02 πŸ‘ 17 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0

THE conference of diatom molecular and cell bio is happening in Ghent this year !
Make sure to submit an abstract !
Flora

20.02.2025 08:34 πŸ‘ 10 πŸ” 8 πŸ’¬ 0 πŸ“Œ 0
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Molecular Life of Diatoms 8 22-26 June 2025, Ghent, Belgium

Want to share your latest breakthroughs on the molecular biology of diatoms? Join us at the Molecular Life of Diatoms conference from 22-26 June 2025 in beautiful historical Ghent, Belgium! Secure your spot here: vibconferences.be/events/molecular-life-of-diatoms-8 #MLD8

17.02.2025 14:46 πŸ‘ 3 πŸ” 2 πŸ’¬ 0 πŸ“Œ 0

πŸ‘‹ could you add me, please?

11.01.2025 13:00 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

And here is a paywall-free link for the New Phytologist version: nph.onlinelibrary.wiley.com/share/VSGUV2....

11.12.2024 13:37 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Open access pre-print available here: www.biorxiv.org/content/10.1...

10.12.2024 13:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Finally, we found that the previously described Pseudo-nitzschia multistriata MRM2 gene shows a conserved mating type-specific response in Cylindrotheca and in Seminavis, providing the first molecular evidence for a shared origin of heterothally in pennate diatoms. (4/4)

10.12.2024 13:51 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Several genes were only expressed in a specific mating type below the size threshold, highlighting how differentiation between mating types only happens when cells are small enough. One example is a local gene cluster of three MT+ and small cell specific genes that are pheromone responsive (3/n)

10.12.2024 13:47 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

Specifically, we partially removed apices from Cylindrotheca closterium cells to create matched "large" and "small" sized cultures for six independent genotypes, three for each mating type. The expression of a small set of just 112 genes differentiated size classes and mating types (2/n)

10.12.2024 13:40 πŸ‘ 0 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Proud to share our latest work, out in @newphyt.bsky.social, where we use single-cell #microsurgery to investigate the molecular fingerprints of size-dependent sexual maturation in diatoms πŸ”₯ (1/n)
nph.onlinelibrary.wiley.com/doi/10.1111/...

10.12.2024 13:35 πŸ‘ 10 πŸ” 8 πŸ’¬ 1 πŸ“Œ 0

As a fellow algae enthusiast, I would love to be added!

30.11.2024 22:20 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0

I would be interested to join as well - we have several experiments running that involve diatoms and heat shock

27.11.2024 11:57 πŸ‘ 0 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0

Can you add me please? Also @evelinepinseel.bsky.social would be a great addition to this list!

19.11.2024 06:54 πŸ‘ 1 πŸ” 0 πŸ’¬ 1 πŸ“Œ 0
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Happy to see that our study on the gene expression behind salinity-induced morphological changes in Pleurosira laevis is now published in Journal of Phycology. Very pleasant collab lead by the Shinya Sato lab.
onlinelibrary.wiley.com/doi/full/10....

07.03.2024 09:26 πŸ‘ 3 πŸ” 0 πŸ’¬ 0 πŸ“Œ 0